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Small circles of extrachromosomal DNA appear to be widespread in mammals

Small circles of extrachromosomal DNA appear to be widespread in mammals | Neurobiology | Scoop.it
A newly identified form of DNA—small circles of non-repetitive sequences—may be widespread in somatic cells of mice and humans, according to a study in this week’s issue of Science. These extrachromosomal bits of DNA, dubbed microDNA, may be the byproducts of microdeletions in chromosomes, meaning that cells all over the body may have their own constellation of missing pieces of DNA.

 

“It’s an intriguing finding,” said James Lupski, a geneticist at Baylor College of Medicine in Houston who did not participate in the research. Most DNA studies use cells drawn from blood, but that snapshot of a person’s genome may not be giving a complete picture, Lupski explained, if cells in other organs have their own set of chromosomal snippets missing.

 

But the findings do not surprise Sabine Mai, who studies genomic instability at the University of Manitoba. Extrachromosomal DNA is a well-studied phenomenon in cells ranging from plants to humans, she says. This research is just renaming an old phenomenon, previously referred to small polydispersed DNA. Small circles of DNA have been identified before, Mai says, though new deep sequencing techniques will allow for a “deeper characterization” of these extrachromosomal snippets.


Via Dr. Stefan Gruenwald
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Blood vessels 'sniff' gut microbes to regulate blood pressure

Blood vessels 'sniff' gut microbes to regulate blood pressure | Neurobiology | Scoop.it
Researchers at The Johns Hopkins University and Yale University have discovered that a specialized receptor, normally found in the nose, is also in blood vessels throughout the body, sensing small molecules created by microbes that line mammalian...
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Convergence of pontine and proprioceptive streams onto multimodal cerebellar granule cells | eLife

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Realtime cerebellum: A large-scale spiking netwo... [Neural Netw. 2013] - PubMed - NCBI

PubMed comprises more than 22 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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Bees Can Sense the Electric Fields of Flowers

Bees Can Sense the Electric Fields of Flowers | Neurobiology | Scoop.it
Flowers are electric billboards! Bumblebees can sense the electric fields of flowers, and detect recently visited ones. …
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An eye for an eye, a newt for a newt: the genomics of tissue regeneration

An eye for an eye, a newt for a newt: the genomics of tissue regeneration | Neurobiology | Scoop.it
On the list of humanity’s priorities, tissue regeneration finds itself near the very top; together with eternal youth and immortality.
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Plasticity of body representations af... [Restor Neurol Neurosci. 2013] - PubMed - NCBI

PubMed comprises more than 22 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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How Neuroscience Will Fight Five Age-Old Afflictions

How Neuroscience Will Fight Five Age-Old Afflictions | Neurobiology | Scoop.it
1) SEIZURES A device delivers targeted drugs to calm overactive neurons For years, large clinical trials have treated people
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Re-evaluating the role of the mammillary bodies in memory | ResearchGate

Re-evaluating the role of the mammillary bodies in memory | ResearchGate | Neurobiology | Scoop.it
Publication » Re-evaluating the role of the mammillary bodies in memory.
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The Remarkable Neuron: Erin Schuman at TEDxCaltech

The Remarkable Neuron: Erin Schuman at TEDxCaltech | Neurobiology | Scoop.it
Erin Schuman is a neurobiologist who studies synapses, the connections between neurons. She was born in San Gabriel, California, and completed her bachelor's degree in psychology at the University of
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In Mysterious Pattern, Math and Nature Converge | Wired Science | Wired.com

In Mysterious Pattern, Math and Nature Converge | Wired Science | Wired.com | Neurobiology | Scoop.it
All complex correlated systems, from Arctic melt ponds to the internet, appear to be governed by the same math as a random matrix.
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'Matrix'-style effortless learning? Vision scientists demonstrate innovative learning method

'Matrix'-style effortless learning? Vision scientists demonstrate innovative learning method | Neurobiology | Scoop.it
It may be possible to use brain technology to learn to play a piano, reduce mental stress or hit a curve ball with little or no conscious effort, new research suggests. It's the kind of thing seen in Hollywood's "Matrix" franchise.
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Semiconductor Nanomembrane Tubes: Three-Dimensional Confinement for Controlled Neurite Outgrowth - ACS Nano (ACS Publications)

Semiconductor Nanomembrane Tubes: Three-Dimensional Confinement for Controlled Neurite Outgrowth - ACS Nano (ACS Publications) | Neurobiology | Scoop.it
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New study shows how seals sleep with only half their brain at a time

New study shows how seals sleep with only half their brain at a time | Neurobiology | Scoop.it
A new study led by an international team of biologists has identified some of the brain chemicals that allow seals to sleep with half of their brain at a time.
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Tongue-tingling interface lets you taste data | KurzweilAI

Tongue-tingling interface lets you taste data | KurzweilAI | Neurobiology | Scoop.it
Tongueduino (credit: Gershon Dublon, Joseph A. Paradiso) Gershon Dublon of the Massachusetts Institute of Technology has devised the Tongueduino --- a small
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Video: Chimpanzees have faster working memory than humans, according to study

Video: Chimpanzees have faster working memory than humans, according to study | Neurobiology | Scoop.it
Chimpanzees have a faster working memory than humans according to a remarkable study showing that it takes them a fraction of a second to remember something that it would take several seconds for humans to memorise.
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Researchers uncover a pathway that stimulates bone growth

Researchers  uncover a pathway that stimulates bone growth | Neurobiology | Scoop.it
(Medical Xpress)—Researchers from the University of Pennsylvania School of Veterinary Medicine have discovered that a protein called Jagged-1 stimulates human stem cells to differentiate into bone-producing cells.
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Igniting a Brain-Computer Interface Revolution – BCI X PRIZE

Igniting a Brain-Computer Interface Revolution – BCI X PRIZE | Neurobiology | Scoop.it
This is a guest post written by entrepreneur, Singularity University alumnus and teaching fellow Rod Furlan. He is an independent researcher in the fields of artificial intelligence, quantitative finance and high-performance computing.

Via David Cearlock
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