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Gayatri Devi, M.D., the Vagus nerve guru and Calm Brain author

Gayatri Devi, M.D., the Vagus nerve guru and Calm Brain author | Neuro-Immune Regulatory Pathways | Scoop.it
Gayatri Devi MD is a neurologist and the Director of the New York Memory Services. She is a Clinical Associate Professor at the New York University School of Medicine.

 

I am reading her book outloud to my wife about 10 pages at a time.  It is calming our brains.  I have become a fan of hers, because she really knows what she is talking about, has a holistic approach that does not abandon good science, and tells her truth like a very interesting story.


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Neuro-Immune Regulatory Pathways
Cross-talk between major neuroendocrine and immune pathways and how this affects immunity
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New Clues to the Neurobiology of Depression | Psych Congress Network

New Clues to the Neurobiology of Depression | Psych Congress Network | Neuro-Immune Regulatory Pathways | Scoop.it
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Viruses and Glucocorticoids ‘Cooperate’ to Induce Interleukin-10 Production: Implications for Stress-Induced Immunosuppression and Exacerbations of Asthma

Viruses and Glucocorticoids ‘Cooperate’ to Induce Interleukin-10 Production: Implications for Stress-Induced Immunosuppression and Exacerbations of Asthma | Neuro-Immune Regulatory Pathways | Scoop.it
A study published in the May 2013 issue of PLoS One may indicate a novel, unrecognized interaction between viruses and the glucocorticoid (GC)-signaling system that results in the induction of interleukin (IL)-10 production by dendritic cells (DCs).
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Acupuncture affects immunity via dopamine-dependent pathway | The BrainImmune Resource: Opinions & views in neuroendocrine immunology, stress-immune interactions

Acupuncture affects immunity via dopamine-dependent pathway | The BrainImmune Resource: Opinions & views in neuroendocrine immunology, stress-immune interactions | Neuro-Immune Regulatory Pathways | Scoop.it
New study provides perhaps the first robust evidence that acupuncture’s effects are translated through specific neuroendocrine and immune pathways.
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Mapping Emotions On The Body: Love Makes Us Warm All Over

Mapping Emotions On The Body: Love Makes Us Warm All Over | Neuro-Immune Regulatory Pathways | Scoop.it
Being happy is indeed a total body experience, according to maps of where people feel emotions.

Via Sophie Martin
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Sophie Martin's curator insight, January 10, 3:54 AM

I was wondering if the "warm" of love and happyness could be re-used to light a lamp for instance .... :) and yes :http://www.odditycentral.com/pics/high-tech-sweater-displays-wearers-emotions-via-integrated-led-lights.html

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Sleep keeps brain fit by clearing waste › News in Science (ABC Science)

Sleep keeps brain fit by clearing waste › News in Science (ABC Science) | Neuro-Immune Regulatory Pathways | Scoop.it
Disease-causing waste that builds up during the day is cleaned out from our brain as we sleep at night, say researchers.

Via David Holloway
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The Internal Clitoris

The Internal Clitoris | Neuro-Immune Regulatory Pathways | Scoop.it

Consider this: In over five million years of human evolution, only one organ has come to exist for the sole purpose of providing pleasure – the clitoris.  It is not required for reproduction.  It doesn’t have a urethra running through it like the penis, and thus, does not urinate.  Its sole function – its singular, wonderful purpose – is to make a woman feel good!!

Sadly, it is precisely because the clitoris has no function apart from female pleasure that science has neglected to study it as intricately as the penis...


Via Dr. Amy Fuller, Sophie Martin
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Dr. Amy Fuller's curator insight, September 3, 2013 10:19 PM

Caution...this scoop isn't for the faint of heart!

Facinating new 3-D imaging of what is actually inside the female genetalia. 

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Computer can read letters directly from the brain - Radboud University

Computer can read letters directly from the brain - Radboud University | Neuro-Immune Regulatory Pathways | Scoop.it
By analysing MRI images of the brain with an elegant mathematical model, it is possible to reconstruct thoughts more accurately than ever before.
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Tachykinins, Bone Marrow and Hematopoiesis | The BrainImmune Resource: Opinions & views in neuroendocrine immunology, stress-immune interactions

Tachykinins, Bone Marrow and Hematopoiesis | The BrainImmune Resource: Opinions & views in neuroendocrine immunology, stress-immune interactions | Neuro-Immune Regulatory Pathways | Scoop.it

In this chapter we attempt to uncover the different roles of tachykinins in human disease homeostatic conditions in particular hematopoiesis within the bone marrow cavity. We also discuss normal synthesis of tachykinins and their receptors, yet focus on their regulation by microRNA, messenger RNA stabilizing proteins, and transcription factors like Restrictive Element-1 Silencing Factor (REST). We discuss the consequence of the tachykinins to pathological conditions such as breast cancer development. We also review the normal processes during their role as neurotransmitters.

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Nerve Growth Factor and Inflammation: A Complex Bidirectional Interaction | The BrainImmune Resource: Opinions & views in neuroendocrine immunology, stress-immune interactions

Nerve Growth Factor and Inflammation: A Complex Bidirectional Interaction | The BrainImmune Resource: Opinions & views in neuroendocrine immunology, stress-immune interactions | Neuro-Immune Regulatory Pathways | Scoop.it

Among the growing number of molecules known to be involved in both neuronal and immune modulation, Nerve Growth Factor (NGF) seems to have a role in this complex network of bi-directional signals between the nervous and immune systems.

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Influence of the Sympathetic Nervous System on Regulatory T cells | The BrainImmune Resource: Opinions & views in neuroendocrine immunology, stress-immune...

Influence of the Sympathetic Nervous System on Regulatory T cells | The BrainImmune Resource: Opinions & views in neuroendocrine immunology, stress-immune... | Neuro-Immune Regulatory Pathways | Scoop.it

Herein is an overview of our observations on the inhibition of the induction of splenic CD4 and CD8+ regulatory T cells, thymic and hepatic regulatory T cells by the ablation of the sympathetic nervous system by the neurotoxin 6-hydroxydopamine (6-OHDA). In contrast, sympathectomy with 6-OHDA induces an elevation in CD4, FoxP3+ regulatory T cells in the spleen and lymph nodes that can mitigate the induction of experimental autoimmune encephalomyelitis. We suggest that the sympathetic influence on the activation and maintenance of different regulatory T cells is a major neuronal influence of the immune system that could be a major factor in chronic stress.

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Claude Bernard, the Father of Modern Physiology and Experimental Medicine | The BrainImmune Resource: Opinions & views in neuroendocrine immunology, stress-immune interactions

Claude Bernard, the Father of Modern Physiology and Experimental Medicine | The BrainImmune Resource: Opinions & views in neuroendocrine immunology, stress-immune interactions | Neuro-Immune Regulatory Pathways | Scoop.it
Claude Bernard was born on 12 July 1813 in the village of Saint-Julien, in France’s Beaujolais region. He was first educated in the church school of
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Turned On By Danger (BBC Documentary)

Turned on by Danger is a profile of Professor Polly Matzinger, sheep dog expert, former bunny girl and arguably the world's best immunologist, who reveals he...

Via Gilbert Faure au nom de l'ASSIM
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The emerging field of contemplative neuroscience | Mindful

The emerging field of contemplative neuroscience | Mindful | Neuro-Immune Regulatory Pathways | Scoop.it
Richard Davidson, Ph.D., on the emergence of contemplative neuroscience and studies on how meditation affects the brain.

Via Maggie Rouman, Gerald P. Kozlowski
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Mercor's curator insight, February 8, 2013 3:42 AM

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Gerald P. Kozlowski's curator insight, March 20, 2013 2:09 AM

It's wonderful to have Dr Davidson's input.

Anthony M Crasto DR.'s comment, September 2, 2013 12:37 AM
NICE
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How To Trick Your Brain To Hold On To Positive Habit Changes

How To Trick Your Brain To Hold On To Positive Habit Changes | Neuro-Immune Regulatory Pathways | Scoop.it

Nearly half of our everyday behaviors tend to be repeated in the same location almost every day, according to research out of Duke University. That means most of the time we are running on autopilot.

 

On average, a habit takes more like 66 days to form, with more intensive habits like doing 50 sit-ups every morning taking around 84 days to form, according to research out of University College of London that Dean references in his book. But these figures will often vary greatly from person to person.

 

Forming habits that stick isn't about finding a magic number. It's about being aware of your behaviors and environment and their effects on your brain. Here are some steps to get started:


Via Vicki Kossoff @ The Learning Factor
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Vicki Kossoff @ The Learning Factor's curator insight, September 4, 3:21 PM

You start strong, with great intentions, but soon that new habit falls to the wayside. Here's how to cement it into your daily life.

CreateLivingOnline's curator insight, September 4, 4:07 PM

#LifeHacks

2discoverRecruitment's curator insight, September 4, 10:31 PM

Start your healthy habits for summer now!

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Brain-mapping projects to join forces

Brain-mapping projects to join forces | Neuro-Immune Regulatory Pathways | Scoop.it

US and European research programmes will begin coordinating research.

 

It seems a natural pairing, almost like the hemispheres of a human brain: two controversial and ambitious projects that seek to decipher the body's control center are poised to join forces.

The European Union’s €1-billion (US$1.3-billion) Human Brain Project (HBP) and the United States’ $1-billion Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative will launch a collaboration later this year, according to government officials involved in both projects.(...) - by Sara Reardon, Nature, 18 March 2014


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Doctors Advise Longer Labor to Avoid C-Sections

Doctors Advise Longer Labor to Avoid C-Sections | Neuro-Immune Regulatory Pathways | Scoop.it

Via The National Organization For The Respect Of Motherhood ( N.O.R.M)
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blu's curator insight, March 18, 9:10 PM

Been there, done that!

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Social Position Drives Gene Regulation of the Immune System

Social Position Drives Gene Regulation of the Immune System | Neuro-Immune Regulatory Pathways | Scoop.it

New research with rhesus macaques shows that dominance rank has a major impact on gene regulation of the immune system


Via Sakis Koukouvis, zorro zhang
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Immune enhancing pathway found - ScienceAlert

Immune enhancing pathway found - ScienceAlert | Neuro-Immune Regulatory Pathways | Scoop.it
ScienceAlert Immune enhancing pathway found ScienceAlert Melbourne researchers have found that even our immune system is subject to performance enhancement, giving immune cells the boost they need to ensure the best team is selected to fight...
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Very long-term memories may be stored in the pattern of holes in the perineuronal net

Very long-term memories may be stored in the pattern of holes in the perineuronal net | Neuro-Immune Regulatory Pathways | Scoop.it

A hypothesis and the experiments to test it propose that very long-term memories, such as fear conditioning, are stored as the pattern of holes in the perineuronal net (PNN), a specialized ECM that envelops mature neurons and restricts synapse formation. The 3D intertwining of PNN and synapses would be imaged by serial-section EM. Lifetimes of PNN vs. intrasynaptic components would be compared with pulse-chase 15N labeling in mice and 14C content in human cadaver brains. Genetically encoded indicators and antineoepitope antibodies should improve spatial and temporal resolution of the in vivo activity of proteases that locally erode PNN. Further techniques suggested include genetic KOs, better pharmacological inhibitors, and a genetically encoded snapshot reporter, which will capture the pattern of activity throughout a large ensemble of neurons at a time precisely defined by the triggering illumination, drive expression of effector genes to mark those cells, and allow selective excitation, inhibition, or ablation to test their functional importance. The snapshot reporter should enable more precise inhibition or potentiation of PNN erosion to compare with behavioral consequences. Finally, biosynthesis of PNN components and proteases would be imaged. (...) - By Roger Y. Tsien, PNAS July 23, 2013 vol. 110 no. 3012456-12461


Via Julien Hering, PhD
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Autonomic Nervous System Control of Leukocyte Distribution: Physiology and Implications for Common Human Diseases | The BrainImmune Resource: Opinions & views in neuroendocrine immunology, stress-i...

Autonomic Nervous System Control of Leukocyte Distribution: Physiology and Implications for Common Human Diseases | The BrainImmune Resource: Opinions & views in neuroendocrine immunology, stress-i... | Neuro-Immune Regulatory Pathways | Scoop.it

Granulocytes express adrenergic receptors and the number and proportion of granulocytes increase by a stimulation of the sympathetic nervous system. Indeed, there are several physiological variations of leukocytes, including neonatal granulocytosis, and a circadian rhythm of granulocytes and lymphocytes (i.e., granulocytosis at daytime and lymphocytosis at night). Severe granulocytosis induced by stress is also associated with the onset of tissue-destructive and autoimmune diseases. We reveal herein that the onset of many common diseases in humans is intimately related to their lifestyle, stress, the subsequent sympathetic nerve activation and granulocytosis.

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Role of the Vagus Nerve at the Neural-Immune Interface | The BrainImmune Resource: Opinions & views in neuroendocrine immunology, stress-immune interactions

Role of the Vagus Nerve at the Neural-Immune Interface | The BrainImmune Resource: Opinions & views in neuroendocrine immunology, stress-immune interactions | Neuro-Immune Regulatory Pathways | Scoop.it

Afferent vagal pathways transmit information to the brain related to peripheral inflammation so as to participate in the activation of adaptive reactions, including fever and sickness behavior. On the other side, efferent vagal pathways inhibit the synthesis and release of pro-inflammatory cytokines by peripheral immune cells.

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Innervation of the Human Thymus and Spleen – an Overview | The BrainImmune Resource: Opinions & views in neuroendocrine immunology, stress-immune interactions

Innervation of the Human Thymus and Spleen – an Overview | The BrainImmune Resource: Opinions & views in neuroendocrine immunology, stress-immune interactions | Neuro-Immune Regulatory Pathways | Scoop.it
The immune and nervous systems are anatomically and functionally interconnected, this cross-talk is evidenced by the dense innervation – mainly sympathetic
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Rejecting Allergens: The Avoidance Behavior | The BrainImmune Resource: Opinions & views in neuroendocrine immunology, stress-immune interactions

Rejecting Allergens: The Avoidance Behavior | The BrainImmune Resource: Opinions & views in neuroendocrine immunology, stress-immune interactions | Neuro-Immune Regulatory Pathways | Scoop.it

The pioneering work of the Nelson Vaz group published the first evidence of behavioral changes as a consequence of allergic reactions, showing that ovalbumin (OVA)-allergic mice avoided drinking an otherwise preferred artificially sweetened solution containing OVA. This aversion is specific, since peanut- or cashew nut-sensitized mice, when offered with a mixture of the grains in natura avoided only the grains containing the allergen they were sensitized to.

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Bartolomeo Eustachius and the Discovery of Adrenal Glands | The BrainImmune Resource: Opinions & views in neuroendocrine immunology, stress-immune interactions

Bartolomeo Eustachius and the Discovery of Adrenal Glands | The BrainImmune Resource: Opinions & views in neuroendocrine immunology, stress-immune interactions | Neuro-Immune Regulatory Pathways | Scoop.it
Bartolomeo Eustachio was born in 1524 in San Severino Marche, a little town situated in the center of Italy and belonging at that time to the Papal States. He
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New LinkedIn Contacts: Aims to Be Your Personal Assistant

New LinkedIn Contacts: Aims to Be Your Personal Assistant | Neuro-Immune Regulatory Pathways | Scoop.it

LinkedIn has announced it is launching a new Linkedin Contacts that aims to create a “personal assistant” for users.

You might be thinking you already have a Contacts section in your LinkedIn account – and you’d be right.  However, this goes well beyond what LinkedIn offers today under the “Contacts” tab.  The new LinkedIn Contacts will reside within LinkedIn and also as a standalone app for iPhone.

What’s new about it?  With the new LinkedIn Contacts you will be able to see information not only about your LinkedIn connections, but also everybody in your address book, calendars and emails. You can have all your professional contacts in one place, instead of scattered around among LinkedIn, email, and other places.

On the official LinkedIn blog, Engineer and Product Specialist Sachin Rekhi writes:

“LinkedIn Contacts brings together all your address books, emails, and calendars, and keeps them up to date in one place. From these sources, we’ll automatically pull in the details of your past conversations and meetings, and bring these details directly onto your contact’s profile.”

(...) - By Joshua Sophy, Small Business Trends, April 29, 2013


Via Julien Hering, PhD
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Julien Hering, PhD's curator insight, May 1, 2013 10:12 AM

LinkedIn Contacts imports all your professional contacts from email and other apps, so you have them in one place. It helps you communicate with contacts.
The new LinkedIn Contacts has a waiting list that you can ask to be added to

BrainImmune's comment, May 11, 2013 2:57 PM
Thanks Julien
Julien Hering, PhD's comment, May 13, 2013 6:31 AM
You're welcome!