Just this weekend I was sitting in a workshop at Sweetwater’s GearFest, listening to Grammy award winning engineer Frank Fillipetti talk about recording and mixing in the modern DAW. At one point in the presentation he displayed images of two identical brain scans of a person. Scan #1 showed the brain activity when listening to music with eyes open. Scan #2 showed brain activity when that same person listened to music with eyes closed. And it showed considerable more brain activity happening.
It turns out, the amygdala (or the emotional center of the brain) increases in activity dramatically when presented with aural stimuli and no visual stimuli. Visual stimuli actually impair our ability to listen critically. The point? Looking at your DAW when mixing is a handicap.