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Industrial natural product chemistry for drug discovery and development

Industrial natural product chemistry for drug discovery and development | Natural products | Scoop.it
In addition to their prominent role in basic biological and chemical research, natural products are a rich source of commercial products for the pharmaceutical and other industries. Industrial natural product chemistry is of fundamental importance for successful product development, as the vast majority (ca. 80%) of commercial drugs derived from natural products require synthetic efforts, either to enable economical access to bulk material, and/or to optimize drug properties through structural modifications. This review aims to illustrate issues on the pathway from lead to product, and how they have been successfully addressed by modern natural product chemistry. It is focused on natural products of current relevance that are, or are intended to be, used as pharmaceuticals. Armin Bauer*a and Mark Brö Nat. Prod. Rep., 2014, Advance Article DOI: 10.1039/C3NP70058E
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Capturing volatile natural products by mass spe...

Capturing volatile natural products by mass spe... | Natural products | Scoop.it
“Covering: up to 2013This review gives a modern methodic overview of how volatile natural products from various sources such as plants, animals, bacteria and fungi can be trapped and how compound identification can be performed even in cases of very...”
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Drug discovery from natural products : Article : Nature Reviews Drug Discovery

Drug discovery from natural products : Article : Nature Reviews Drug Discovery | Natural products | Scoop.it
“"#Natural products have proved to be a rich source of therapeutic agents." http://t.co/X16xEZCbYh”;
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Natural fungal products could offer potential Alzheimer's therapy

Natural fungal products could offer potential Alzheimer's therapy | Natural products | Scoop.it
“A team of researchers at the University of Kansas, including T. Chris Gamblin, associate professor of molecular biosciences, and Berl Oakley, Irving S.”
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