Nanotechnology & Health
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a collection of articles about nanomaterials and health
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foodconsumer.org - Silica in food, dietary supplements damages the liver

foodconsumer.org - Silica in food, dietary supplements damages the liver | Nanotechnology & Health | Scoop.it
Thursday Feb 14, 2013 (foodconsumer.org) -- A new study published in  Advanced Materials Research suggests that food consumers may be better off avoiding dietary supplements and processed foods that contain silica and other nanoparticles as the study found that silica which is also known as silicone dioxide can damage the liver.
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The comparative immunotoxicity of mesoporous silica nanoparticles and colloidal silica nanoparticles in mice

The comparative immunotoxicity of mesoporous silica nanoparticles and colloidal silica nanoparticles in mice | Nanotechnology & Health | Scoop.it
Results: There was no overt sign of clinical toxicity in either MPS- or Col-treated mice. However, MPS NPs led to significant increases in liver and spleen weight and splenocyte proliferation. Mice treated with MPS NPs showed altered lymphocyte populations (CD3+, CD45+, CD4+, and CD8+) in the spleen, increased serum IgG and IgM levels, and histological changes. Despite slight changes in lymphocyte populations in the spleen, Col NPs did not alter other immunological factors.
Conclusion: The results indicate that in vivo exposure to MPS NPs caused more damage to systemic immunity than that of Col NPs through the dysregulation of the spleen. The results for in vivo data are inconsistent with those for in vitro data, which show lower cytotoxicity for MPS NPs. These results suggest the importance of verifying biocompatibility both in vitro and in vivo during the design of new nanomaterials.
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