"The U.S. Environmental Protection Agency (EPA) recently faced tough questioning from the U.S. Court of Appeals for the Ninth Circuit over its decision to conditionally approve a pesticide product containing nanosilver as the active ingredient. The antimicrobial pesticide product, HeiQ AGS-20, contains microscopic particles of silver and has been applied to textiles such as clothes, blankets, and pillowcases, in an attempt to suppress odor and bacterial growth... Because of their size, nanoparticles can be easily inhaled, absorbed by skin contact, or ingested. Little to no information is known about the fate or effects nanoparticles, specifically nanosilver, can have on the digestive tract, lung, or skin of those that are exposed to these particles. Research is still ongoing to investigate whether nanosize particles cause pulmonary inflammation as well as systemic effects, and whether they translocate from the lungs to other organs such as the liver, kidney or brain. Preliminary research with laboratory rats has found that nanosilver can traverse into the brain, and can induce neuronal degeneration and necrosis (death of cells or tissue) by accumulating in the brain over a long period of time. Low doses of nanosilver can also make bacteria stronger and more resistant."