Nanotechnology & ...
Follow
Find tag "silica"
658 views | +0 today
Nanotechnology & Health
a collection of articles about nanomaterials and health
Your new post is loading...
Your new post is loading...
Scooped by Environmental Illness Network Minnesota
Scoop.it!

EC concerned of use of silica in nano form - Cosmetics Design-Europe.com

EC concerned of use of silica in nano form - Cosmetics Design-Europe.com | Nanotechnology & Health | Scoop.it
The European Commission has called on the Scientific Committee on Consumer Safety (SCCS) for a full risk assessment on the safe use of the nano form of silica in cosmetic products.
more...
No comment yet.
Scooped by Environmental Illness Network Minnesota
Scoop.it!

The comparative immunotoxicity of mesoporous silica nanoparticles and colloidal silica nanoparticles in mice

The comparative immunotoxicity of mesoporous silica nanoparticles and colloidal silica nanoparticles in mice | Nanotechnology & Health | Scoop.it
Results: There was no overt sign of clinical toxicity in either MPS- or Col-treated mice. However, MPS NPs led to significant increases in liver and spleen weight and splenocyte proliferation. Mice treated with MPS NPs showed altered lymphocyte populations (CD3+, CD45+, CD4+, and CD8+) in the spleen, increased serum IgG and IgM levels, and histological changes. Despite slight changes in lymphocyte populations in the spleen, Col NPs did not alter other immunological factors.
Conclusion: The results indicate that in vivo exposure to MPS NPs caused more damage to systemic immunity than that of Col NPs through the dysregulation of the spleen. The results for in vivo data are inconsistent with those for in vitro data, which show lower cytotoxicity for MPS NPs. These results suggest the importance of verifying biocompatibility both in vitro and in vivo during the design of new nanomaterials.
more...
No comment yet.
Scooped by Environmental Illness Network Minnesota
Scoop.it!

foodconsumer.org - Silica in food, dietary supplements damages the liver

foodconsumer.org - Silica in food, dietary supplements damages the liver | Nanotechnology & Health | Scoop.it
Thursday Feb 14, 2013 (foodconsumer.org) -- A new study published in  Advanced Materials Research suggests that food consumers may be better off avoiding dietary supplements and processed foods that contain silica and other nanoparticles as the study found that silica which is also known as silicone dioxide can damage the liver.
more...
No comment yet.
Scooped by Environmental Illness Network Minnesota
Scoop.it!

CAMS used to determine biological effects of silica nanoparticles

"However, as the potential uses of SiNPs have increased, research looking into the biological effects and toxicity has not kept up to speed. Studies have shown that inhalation of microcrystalline silica may be linked with the pulmonary disease silicosis in humans. Chronic inhalation studies in rats have been associated with pulmonary fibrosis and cancer, and exposure to microscale amporphous silica has been linked to inflammation, granuloma formation and emphysema. A complete understanding of the size, shape, and composition-dependent interactions of SiNPs with biological systems is lacking, largely due to suitable analytical methods.

 

The Livermore PK analysis showed that SiNPs were rapidly cleared from the circulatory system (the "central compartment" in PK models) and were distributed to various body tissues, where they persisted over the eight-week time course of the study, raising questions about the potential for bioaccumulation and associated long-term effects."

more...
No comment yet.