Therapeutic peptide
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PeptiMimesis - New biotech startup developing next generation therapeutic peptides in immuno-oncology, oncology and immune diseases

PeptiMimesis - New biotech startup developing next generation therapeutic peptides in immuno-oncology, oncology and immune diseases | Therapeutic peptide | Scoop.it
(1) Transparency Market Research - Peptide Therapeutics Market: Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2012-2018 http://www.prnewswire.com/news-releases/global-peptide-therapeutics-market-to-value-usd-254-billion-by-2018-transparency-market-research-276942881.html...
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Promising Peptide Compounds Against a Cancer Target

Promising Peptide Compounds Against a Cancer Target | Therapeutic peptide | Scoop.it
Advances in new treatments for diseases, including cancer, come about from innovative research with therapeutic potential.
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PeptiDream inks peptide discovery collaboration pact with Teijin Pharma - pharmabiz.com

PeptiDream inks peptide discovery collaboration pact with Teijin Pharma - pharmabiz.com | Therapeutic peptide | Scoop.it
PeptiDream inks peptide discovery collaboration pact with Teijin Pharma
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iBio Inc. Discovers Efficacy of Orally-Delivered Peptides - Pharmaceutical Processing

iBio Inc. Discovers Efficacy of Orally-Delivered Peptides - Pharmaceutical Processing | Therapeutic peptide | Scoop.it
iBio, Inc. announces further discoveries by iBio's scientific collaborator, demonstrating efficacy of an orally-dosed peptide version of iBio's protein candidate against fibrotic diseases.
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Peptide measurement predicts Ebola deadliness

Peptide measurement predicts Ebola deadliness | Therapeutic peptide | Scoop.it
New data show that the Replikin count of the Ebola virus increased 16-fold in 2013 before the current outbreaks--an indication that the current strain is highly transmissible and dangerous.
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New protein structure could help treat Alzheimer's, related diseases - Medical Xpress

New protein structure could help treat Alzheimer's, related diseases - Medical Xpress | Therapeutic peptide | Scoop.it
Medical Xpress New protein structure could help treat Alzheimer's, related diseases Medical Xpress University of Washington bioengineers have a designed a peptide structure that can stop the harmful changes of the body's normal proteins into a...
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Aegis Awarded US Patent for Stable “Shirt-Pocket” Insulin Suitable for Metered Nasal Spray or Injection | Aegis Therapeutics LLC

Aegis Awarded US Patent for Stable “Shirt-Pocket” Insulin Suitable for Metered Nasal Spray or Injection | Aegis Therapeutics LLC | Therapeutic peptide | Scoop.it
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Peptide Therapeutic Candidate for Treating Conditions Caused by gamma-Herpesvirsus-NDSU Research Foundation

Peptide Therapeutic Candidate for Treating Conditions Caused by gamma-Herpesvirsus-NDSU Research Foundation | Therapeutic peptide | Scoop.it
Epstein-Barr, Kaposi’s Sarcoma, and other gamma-herpesviruses (yHV) infect over 95% of humans. The viruses are normally kept in check by the immune system, but (especially in stressed, or immunoco...
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Zealand Pharma A/S - Zealand presented new data on two novel peptide ... - Wall Street Journal

Zealand Pharma A/S - Zealand presented new data on two novel peptide ... - Wall Street Journal | Therapeutic peptide | Scoop.it
Zealand Pharma A/S - Zealand presented new data on two novel peptide ...
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Synthetic small molecule may help chemo get into brain

Synthetic small molecule may help chemo get into brain | Therapeutic peptide | Scoop.it
A synthetic peptide carrier that crosses the bloodbrain barrier in lab mice offers potential as a vehicle to deliver chemotherapy and other drugs into the brain.
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Antimicrobial Peptide Molecule Coatings May Help Block Human Infections - Azom.com

Antimicrobial Peptide Molecule Coatings May Help Block Human Infections - Azom.com | Therapeutic peptide | Scoop.it
Azom.com Antimicrobial Peptide Molecule Coatings May Help Block Human Infections Azom.com The WPI team is engineering surfaces with molecules called antimicrobial peptides (AMPs), several of which have been extracted from fish gills where they...
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AstraZeneca's Bydureon achieves better glycaemic control than insulin glargine in type 2 diabetes - Drug Development Technology

UK-based AstraZeneca has reported results from its longest, randomised, head-to-head DURATION-3 trial of exenatide once-weekly, a long-acting glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes in adult patients...
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Cancer Vaccine Development: Using Synthetic Peptides to Penetrate Cell Membrane

Cancer Vaccine Development: Using Synthetic Peptides to Penetrate Cell Membrane | Therapeutic peptide | Scoop.it
Dr. Gruber: We successfully addressed the problem of inadequate intracellular delivery of tumor- specific antigens (TSAs) to dendritic cells (DCs) by ...
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Software optimized on Mira advances design of mini-proteins for medicines, materials

Software optimized on Mira advances design of mini-proteins for medicines, materials | Therapeutic peptide | Scoop.it
Scientists are using Mira to virtually design unique, artificial peptides, or short proteins. Peptides have the best properties of two different classes of medical drugs today and could enable future, peptide-based medicines with few side effects. As researchers begin to develop new peptides, they are optimizing their in-house software to test thousands of potential peptide structure designs in tandem, requiring a state-of-the-art supercomputer.
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Lipotec launches new anti-pollution active based on skin care peptides

Lipotec launches new anti-pollution active based on skin care peptides | Therapeutic peptide | Scoop.it
Ingredient supplier Lipotec has announced its latest functional ingredient, Pollushield, which targets skin protection from urban pollution by helping to prevent the accumulation of pollution particles in the epidermis.
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Wasp Venom Peptide Selectively Punctures Cancer Cell Membranes - The Biological SCENE

Wasp Venom Peptide Selectively Punctures Cancer Cell Membranes - The Biological SCENE | Therapeutic peptide | Scoop.it
The Biological SCENE
Wasp Venom Peptide Selectively Punctures Cancer Cell Membranes
The Biological SCENE
The peptide bound to the PC/PS membrane, but the pores it made were small enough for the membrane to seal itself.
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Pfizer joins "Immunotherapy Gold Rush"

Pfizer joins "Immunotherapy Gold Rush" | Therapeutic peptide | Scoop.it

Pfizer Inc. (NYSE:PFE) and Merck & Co. Inc. (NYSE: MRK), known as MSD outside the United States and Canada, through a subsidiary, announced today that they have entered into an agreement to explore the therapeutic potential of the combination of Pfizer’s crizotinib (XALKORI®) with Merck’s investigational anti-PD-1 antibody pembrolizumab, in a Phase 1b clinical study evaluating the safety and tolerability of the combination in patients with ALK-positive advanced or metastatic non-small cell lung cancer (NSCLC).  The financial terms of the agreement were not disclosed. 
 

 

Both companies previously announced plans to evaluate the safety and efficacy of pembrolizumab in combination with Pfizer’s small molecule kinase inhibitor axitinib (INLYTA®) in patients with renal cell carcinoma.  Separately, pembrolizumab plus Pfizer’s PF-05082566 (PF-2566), an investigational immuno-oncology agent that targets the human 4-1BB receptor, will be evaluated in multiple cancer types.  These studies are expected to begin enrollment later this year.
 
About Pembrolizumab
Pembrolizumab (MK-3475) is an investigational, humanized, monoclonal antibody against PD-1 designed to reactivate anti-tumor immunity.  Pembrolizumab exerts dual ligand blockade of the PD-1 pathway by inhibiting the interaction of PD-1 on T cells with its ligands PD-L1 and PD-L2.
 
Pembrolizumab is currently being evaluated across more than 30 types of cancers, as monotherapy and in combination.  It is anticipated that by the end of 2014, the pembrolizumab development program will grow to more than 24 clinical trials, enrolling an estimated 6,000 patients at nearly 300 clinical trial sites worldwide.  For information about Merck’s oncology clinical studies, please visit http://www.merck.com/clinical-trials/index.html.
 
XALKORI® (crizotinib) Indication and Important Safety Information
XALKORI is a kinase inhibitor indicated for the treatment of patients with metastatic non-small cell lung cancer (NSCLC) whose tumors are anaplastic lymphoma kinase (ALK)-positive as detected by an FDA-approved test.
 


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Krishan Maggon 's curator insight, August 26, 2014 11:07 AM

It is a relative late entry for Pfizer which let several blockbuster ooncology drug slip through its R&D evaluation and make fortunes for other smaller biotech companies taking the risk.

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Peptide-based Drug Discovery & Development ...

Peptide-based Drug Discovery & Development ... | Therapeutic peptide | Scoop.it
Temple University; Sponsored by Common Misconceptions. Although biotechnology investors and preclinical pharmacology experts may not always concur, peptide ...
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More than glitter: How gold nanoparticles easily penetrate cells, making them useful for delivering drugs

More than glitter: How gold nanoparticles easily penetrate cells, making them useful for delivering drugs | Therapeutic peptide | Scoop.it
A special class of tiny gold particles can easily slip through cell membranes, making them good candidates to deliver drugs directly to target cells.

Via Jocelyn Stoller
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A Doctor’s Quest to Save People by Injecting Them With Scorpion Venom | Magazine | WIRED

A Doctor’s Quest to Save People by Injecting Them With Scorpion Venom | Magazine | WIRED | Therapeutic peptide | Scoop.it
Because it’s so late on a Monday afternoon, there is a listless vibe inside the University of Washington lecture hall where Jim Olson is about to speak...
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Synthetic Peptide Non-Covalently Transports Cancer Drugs Across the Blood-Brain Barrier

Synthetic Peptide Non-Covalently Transports Cancer Drugs Across the Blood-Brain Barrier | Therapeutic peptide | Scoop.it
Cancer researchers have used a novel synthetic peptide to transport ... blood-brain barrier, they are not able to kill brain tumor cells inside the brain.
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Fungal protein found to cross blood-brain barrier

Fungal protein found to cross blood-brain barrier | Therapeutic peptide | Scoop.it
In a remarkable series of experiments on a fungus that causes cryptococcal meningitis, a deadly infection of the membranes that cover the spinal cord and brain, investigators at UC Davis have isolated a protein that appears to be responsible for the fungus’ ability to cross from the bloodstream into the brain.
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Zealand Pharma A/S - Presentation of several Zealand peptide therapeutics at ... - Wall Street Journal

Zealand Pharma A/S - Presentation of several Zealand peptide therapeutics at ... - Wall Street Journal | Therapeutic peptide | Scoop.it
Zealand Pharma A/S - Presentation of several Zealand peptide therapeutics at ...
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Synthetic Peptide Allows Chemo Drugs to Slip Across Blood-Brain Barrier - Genetic Engineering News

Synthetic Peptide Allows Chemo Drugs to Slip Across Blood-Brain Barrier - Genetic Engineering News | Therapeutic peptide | Scoop.it
Synthetic Peptide Allows Chemo Drugs to Slip Across Blood-Brain Barrier Genetic Engineering News Such was the thinking of researchers at the Mayo Clinic, who have demonstrated in a mouse model that their recently developed synthetic peptide carrier...
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A New Peptide Tackles Infections, Biofilms, & Antibiotic Resistance

A New Peptide Tackles Infections, Biofilms, & Antibiotic Resistance | Therapeutic peptide | Scoop.it
We may have a new weapon against antibiotic resistance. My @PopSci column reveals the power of the peptide. http://t.co/PVbl9oK5D8 #AMR
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