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Belly Button Biodiversity

Belly Button Biodiversity | Microbial World | Scoop.it

The diversity on our bodies is, like any biological diversity, fascinating and full of awe and we want to share the joy of discovering it, one body part at a time. You give us a sample, we will grow and identify the bacteria, and you get the results. Meet your personal ecosystem, in color! With time we will not only grow the microbes off of your parts, we will sequence them, to know the easy to cultivate species but also all the rest. The life on us knows no celebrity, or rather it knows them as well as it knows the rest of us. Lady Gaga may live the wild life, but she also hosts it.

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Microbial World
Microbial life is everywhere - a largely invisible world of astonishing metabolic diversity that helped to create the biosphere and that continues to support life on earth. In fact, there are more bacterial cells inside your gut and on your skin than there are cells in your entire body. So, we are not only living in a microbial world… we are microbial worlds!”


This Curation Blog aims to be a comprehensive and entertaining source of microbial news.


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Nutrition & Diabetes - Correlation network analysis reveals relationships between diet-induced changes in human gut microbiota and metabolic health

Nutrition & Diabetes - Correlation network analysis reveals relationships between diet-induced changes in human gut microbiota and metabolic health | Microbial World | Scoop.it

Recent evidence suggests that the gut microbiota plays an important role in human metabolism and energy homeostasis and is therefore a relevant factor in the assessment of metabolic health and flexibility. Understanding of these host–microbiome interactions aids the design of nutritional strategies that act via modulation of the microbiota. Nevertheless, relating gut microbiota composition to host health states remains challenging because of the sheer complexity of these ecosystems and the large degrees of interindividual variation in human microbiota composition.

We assessed fecal microbiota composition and host response patterns of metabolic and inflammatory markers in 10 apparently healthy men subjected to a high-fat high-caloric diet (HFHC, 1300 kcal/day extra) for 4 weeks. DNA was isolated from stool and barcoded 16S rRNA gene amplicons were sequenced. Metabolic health parameters, including anthropomorphic and blood parameters, where determined at t=0 and t=4 weeks. A correlation network approach revealed diet-induced changes in Bacteroides levels related to changes in carbohydrate oxidation rates, whereas the change in Firmicutes correlates with changes in fat oxidation. These results were confirmed by multivariate models. We identified correlations between microbial diversity indices and several inflammation-related host parameters that suggest a relation between diet-induced changes in gut microbiota diversity and inflammatory processes.This approach allowed us to identify significant correlations between abundances of microbial taxa and diet-induced shifts in several metabolic health parameters. Constructed correlation networks provide an overview of these relations, revealing groups of correlations that are of particular interest for explaining host health aspects through changes in the gut microbiota.
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Microbe community changes may reduce Amazon's ability to lock up carbon dioxide

Microbe community changes may reduce Amazon's ability to lock up carbon dioxide | Microbial World | Scoop.it
UT Arlington researchers focusing on the Amazon recently found that widespread conversion from rainforest to pastureland has significant effects on microorganism communities that may lead to a reduction in the region's role as a reservoir for...
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Exploring host-microbiota interactions | Nutraceuticals Now

Exploring host-microbiota interactions | Nutraceuticals Now | Microbial World | Scoop.it
Guus Roeselers's insight:

The role of our intestinal microbiota reaches far beyond fermentation of indigestible food components. Apart from immunological functions, they have a major impact on our metabolic and perhaps even mental health. Dutch research organization TNO is exploring this exciting field, known as host-microbiota interactions, and is developing and integrating a range of advanced models, techniques and trials. The insights generated will support manufacturers in the development of functional foods targeted at, for example, obesity.

The intestinal microbiota is frequently referred to as “an extra organ in the human body”. This is not surprising, given that our intestines contain up to 100 trillion bacteria, about 10 times more than there are cells in the body. The intestinal microbiota exert a wide range of functions: from playing a key role in the fermentation of indigestible food leftovers, to producing components that benefit intestinal epithelial cells and help inhibit attachment of pathogenic bacteria to the intestinal wall.

‘The intestinal microbiota affect not only our immune system, but also our metabolic and mental health’...

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Draft genome sequence of Francisella tularensis subsp. holarctica BD11-00177

Draft genome sequence of Francisella tularensis subsp. holarctica BD11-00177 | Microbial World | Scoop.it

Francisella tularensis is a facultative intracellular bacterium in the class Gammaproteobacteria. This strain is of interest because it is the etiologic agent of tularemia and a highly virulent category A biothreat agent. Here we describe the draft genome sequence and annotation of Francisella tularensis subsp. holarctica BD11-00177, isolated from the first case of indigenous tularemia detected in The Netherlands since 1953. Whole genome DNA sequence analysis assigned this isolate to the genomic group B.FTNF002–00, which previously has been exclusively reported from Spain, France, Italy, Switzerland and Germany. Automatic annotation of the 1,813,372 bp draft genome revealed 2,103 protein-coding and 46 RNA genes.

 

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Yeast: Love and Fear, Death and Beer

Yeast: Love and Fear, Death and Beer | Microbial World | Scoop.it
Single-celled fungi all around us do so much good and so much bad.
Guus Roeselers's insight:

There’s a strong case to be made that the first species cultivated by humankind was brewer’s yeast, and generations of microbiologists will drink to that.

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PLOS ONE: Comparative Genomic Analysis of Mycobacterium tuberculosis Drug Resistant Strains from Russia

PLOS ONE: Comparative Genomic Analysis of Mycobacterium tuberculosis Drug Resistant Strains from Russia | Microbial World | Scoop.it
PLOS ONE: an inclusive, peer-reviewed, open-access resource from the PUBLIC LIBRARY OF SCIENCE. Reports of well-performed scientific studies from all disciplines freely available to the whole world.

Via Dmitry Alexeev
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Dmitry Alexeev's curator insight, February 21, 2013 4:00 AM

Long way for our article - but finally published - yet there is more to come on TB

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‘Mini gut’ technology aims to make probiotic research more efficient and cheaper, says TNO

‘Mini gut’ technology aims to make probiotic research more efficient and cheaper, says TNO | Microbial World | Scoop.it
A new technology that utilises intestinal stem cells to grown mini gut structures in the lab promises to help probiotic researchers achieve efficient and cost effective research, according to TNO.
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Clara Belzer's curator insight, February 28, 2013 6:57 AM

I imagine it could also be helpfull in studying microbiota associated disases

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Emerald Cockroach Wasp Is Both Neurochemist And Microbiologist - Science News - redOrbit

Emerald Cockroach Wasp Is Both Neurochemist And Microbiologist - Science News - redOrbit | Microbial World | Scoop.it
We all remember the dinner scene in the hit 1979 film ‘Alien’. Everything seemed fine, when all of a sudden an alien parasite emerged from the chest cavity of Ian Holm.
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Emerald Cockroach Wasp larvae can feed on "zombified cockroaches"  by using a potent antimicrobial

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Microbial Life Beneath the Ice | The Scientist Magazine®

Microbial Life Beneath the Ice | The Scientist Magazine® | Microbial World | Scoop.it
Researchers uncover a diverse microbial community living beneath 27 meters of ice in Antarctica’s Lake Vida.
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FOOD TECHNOLOGIST's curator insight, June 13, 2013 9:46 PM

Microbial Life Beneath the Ice

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Belly Button Biodiversity

Belly Button Biodiversity | Microbial World | Scoop.it

The diversity on our bodies is, like any biological diversity, fascinating and full of awe and we want to share the joy of discovering it, one body part at a time. You give us a sample, we will grow and identify the bacteria, and you get the results. Meet your personal ecosystem, in color! With time we will not only grow the microbes off of your parts, we will sequence them, to know the easy to cultivate species but also all the rest. The life on us knows no celebrity, or rather it knows them as well as it knows the rest of us. Lady Gaga may live the wild life, but she also hosts it.

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Fecal microbiota transplant from mother cures ailing toddler

Fecal microbiota transplant from mother cures ailing toddler | Microbial World | Scoop.it
As a young mom with a very sick toddler, Tatum Williams would have done anything -- no matter how odd -- to make her baby better.
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Bacteria Do Battle

Bacteria Do Battle | Microbial World | Scoop.it
Rival colonies of the bacteria Paenibacillus dendritiformis can produce a lethal chemical that keeps competitors at bay. When competing colonies get too close poisons are unleashed, creating a toxic no-man's land in between.
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Electric Bugs: New Microbe Forms Living, Deep-Sea Power Cables | Wired Science | Wired.com

Electric Bugs: New Microbe Forms Living, Deep-Sea Power Cables | Wired Science | Wired.com | Microbial World | Scoop.it
The world's deep seafloors are dark and airless places, but vast swaths may pulse gently with energy conducted through a type of newly discovered bacteria that forms living electrical cables.
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FOOD TECHNOLOGIST's curator insight, June 13, 2013 9:48 PM

Electric Bugs: New Microbe Forms Living, Deep-Sea Power Cables

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Creative Minds: Can Microbes Influence Mental Health?

Creative Minds: Can Microbes Influence Mental Health? | Microbial World | Scoop.it
Gut bacteria could be affecting your thought process.
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Gut microbes linked to improving autism symptoms

Gut microbes linked to improving autism symptoms | Microbial World | Scoop.it
"Groundbreaking" research linking gut microbes to autism could lead to a probiotic therapy for improving the symptoms of autism.
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Building 3-D Microbial Communities | The Scientist Magazine®

Building 3-D Microbial Communities | The Scientist Magazine® | Microbial World | Scoop.it
Researchers apply a 3-D printing technique to structure populations of bacteria in a 3-dimensional environment.
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Ex vivo systems to study host–microbiota interactions in the gastrointestinal tract

Ex vivo systems to study host–microbiota interactions in the gastrointestinal tract | Microbial World | Scoop.it

It is increasingly apparent that the microbial ecosystems in the mammalian gastrointestinal tract play an intricate role in health and disease. There is a growing interest in the development of targeted strategies for modulating health through the modification of these microbiota.

Ecologists are faced with the challenge of understanding the structure and function of ecosystems, the component parts of which interact with each other in complex and diffuse ways. The human gut microbiota, with its high species richness and diversity (up to 1000 bacterial species per individual) including members of all three domains of life, situated in the dynamic environment of the gastrointestinal tract, is probably among the most complex ecosystems on this planet.

In order to elucidate the mechanistic foundations, and physiological significance, of beneficial or pathogenic relationships between the gut microbiota and their hosts, researchers require tractable model ecosystems that allow to recapitulate and investigate host–microbe and microbe–microbe interactions. This review discusses ex vivo gastrointestinal models systems that can be used to gain mechanistic insights into the emergent properties of the host–microbial superorganism.

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Dmitry Alexeev's curator insight, October 1, 2013 11:51 AM

Do you think it is ever possible to construct an ex-vivo system for that?

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“10” Predictions for the Future of Your (Microbial) Health | Guest Blog, Scientific American Blog Network

“10” Predictions for the Future of Your (Microbial) Health | Guest Blog, Scientific American Blog Network | Microbial World | Scoop.it
Every day it seems like some new discovery is revealed about microbial life on our bodies, in our bodies and around our homes. The tendency ...
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Intestinal Microbiota Containing Barnesiella Sp... [Infect Immun. 2013] - PubMed - NCBI

Intestinal Microbiota Containing Barnesiella Sp... [Infect Immun. 2013] - PubMed - NCBI | Microbial World | Scoop.it
Guus Roeselers's insight:

Fecal transplant clears vancomycin-resistant enterococci (VRE) from mice guts. Findings could be useful for development of new pre- and probiotics.

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Dmitry Alexeev's curator insight, June 28, 2013 12:04 AM

there is more and more and fecal transplants 

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Gut Bacteria Conspired in Melamine Poisonings - ScienceNOW

Gut Bacteria Conspired in Melamine Poisonings - ScienceNOW | Microbial World | Scoop.it
Gut Bacteria Conspired in Melamine Poisonings - ScienceNOW
Guus Roeselers's insight:

Remember the 2008 melamine contamination of formula in China? Nearly 300,000 infants got sick, at least six died. Now, a study in rats implicates toxicity arises from gut microbiota converting melamine to cyanuric acid.

[Zheng et al., (2013) Science 5:172ra22]

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Pregnancy alters resident gut microbes

Pregnancy alters resident gut microbes | Microbial World | Scoop.it

"...Women's gut microbe populations change as pregnancy advances, becoming more like those of people who might develop diabetes. These changes, which do not seem to damage maternal health, correspond with increases in blood glucose and fat deposition thought to help a mother nourish her child...."

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TEDx Delft: My microbial self & I

TEDx Delft: My microbial self & I | Microbial World | Scoop.it

We live in a microbial world; both from an evolutionary, biochemical, and an ecological perspective.
Our bodies are no exception. The mammalian gut harbors microorganisms (the microbiota) of vast phylogentic, genomic, and metabolic diversity, and recent years have seen a rapid development in the techniques for studying these complex microbial ecosystems. It is increasingly apparent that the GIT microbiota plays an intricate role in human health and disease.
In the spirit of ideas worth spreading, TEDx is a program of local, self-organized events that bring people together to share a TED-like experience.

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Dmitry Alexeev's curator insight, December 24, 2012 4:12 AM

this one is popular on microbes

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"Water Warm Enough for Microbial Life Existed at Mars' Impact Craters" --New Research

"Water Warm Enough for Microbial Life Existed at Mars' Impact Craters" --New Research | Microbial World | Scoop.it
Hydrothermal fractures around Martian impact craters may have been a habitable environment for microbial life, according to new research that determined that water temperatures on the Red Planet ranged from 50°C to 150°C sufficiently warm enough to...
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Chimp and Human Gut Bacteria Nearly Identical

Chimp and Human Gut Bacteria Nearly Identical | Microbial World | Scoop.it
The findings suggest gut bacteria patterns evolved before chimps and humans split.

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FOOD TECHNOLOGIST's curator insight, June 13, 2013 9:47 PM

Chimp and Human Gut Bacteria Nearly Identical

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Bacteria are social microorganisms: MIT researchers | KurzweilAI

Bacteria are social microorganisms: MIT researchers | KurzweilAI | Microbial World | Scoop.it
Distribution of antagonistic interactions in relationship to Vibrio phylogeny and genetic distance.
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