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The FDA, Surrogate Endpoints, And Blood Pressure Drugs Forbes With few exceptions, current labeling for antihypertensive drugs includes only the information that these drugs are indicated to reduce blood pressure; the labeling does not include...
Via Aviva Lev-Ari, PhD, RN
Two new reports issuing in Science Translational Medicine (STM) today showcase the potential of teams of scientists working together to solve increasingly complex medical problems.
Isoprostanes are a group of prostaglandin-like compounds that are produced by the reaction of free radicals with arachidonic acid, including arachidonic esters in phospholipids.
Interactive web-based biological databases and softwares for life-scientists and researchers.
Two signaling pathways essential to normal human development -- the Wnt/Wingless and epidermal growth factor receptor pathways -- interact in ways that can promote tumor cell invasion and metastasis, researchers reported.
A new genome-wide association study of more than 6,000 people has identified seven new genetic regions associated with pulmonary fibrosis.
Researchers have created a platform detailing all atomic data on protein structures and protein interactions for eight organisms.
Via Loiret David
A report on the results of the first large-scale community-based critical assessment of protein function annotation (CAFA) experiment.
Via Loiret David
Side effects are a major reason that drugs are taken off the market and a major reason why patients stop taking their medications, but scientists are now reporting the development of a new way to predict those adverse reactions ahead of time.
Via Ramesh S Donadi, Loiret David
PLOS Computational Biology is an open-access (Underlying Molecular & Network Level Mechanisms in Evolution of #Robustness in Gene Regulatory #Networks http://t.co/9N0Lc7rX #futuremed)...
Via Loiret David
by Martin H. Schaefer, Tiago J. S. Lopes, Nancy Mah, Jason E. Shoemaker, Yukiko Matsuoka, Jean-Fred Fontaine, Caroline Louis-Jeune, Amie J. Eisfeld, Gabriele Neumann, Carol Perez-Iratxeta, Yoshihiro Kawaoka, Hiroaki Kitano, Miguel A.
Via Loiret David
(Phys.org)—An ingenious new technique is making it quicker and easier for scientists to identify the function of uncharacterized proteins in cells.
Via Loiret David
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Heritage-DREAM, National Cancer Institute Breast Cancer Network Inference ...
Research news from leading universities (Interesting approach.
RT @NatRevNeurol: On day four of #ParkinsonsAwarenessWeek check out this Review from Parnetti et al. on CSF biomarkers in PD http://t.co/nbUtIHLbdG (£)
RT @DrKhouryCDC: Coming age of data science in medicine: emergence of translational bioinformatics #JAMIA http://t.co/BXV4WZFm8j
Overexpression of receptor tyrosine kinase Met has frequently been found in cholangiocarcinoma.
The genome of a primitive fish called a coelacanth contains DNA that could reveal how fish evolved limbs to colonize land (Genome of the #Coelacanth has been sequenced; DNA makes limbs sprout in mice http://t.co/EpMFJVBCjJ)...
Evolution of Proteins Shows Quick Folders are the Best Scicasts The group of Gustavo Caetano-Anolles, head of the Evolutionary Bioinformatics Laboratory at Urbana-Champaign, had originally classified most structurally known proteins from the...
Via Loiret David
Signaling proteins often form dynamic protein-protein interaction (PPI) complexes to achieve multi-functionality.
Via Loiret David
The AvrPiz-t gene encodes a small protein predicted to be secreted that shows no homology to known proteins and is 108 amino acids in length. AvrPiz-t can suppress programmed cell death (PCD) induced by BAX in tobacco, suggesting that it might contribute to the pathogenicity of M. oryzae. These data suggested that AvrPiz-t functions primarily as a virulence effector contributing to the pathogenicity of M. oryzae. To further understand the mechanism of the pathogenicity-associated function of AvrPiz-t, we determined its solution structure.
Via Elsa Ballini, Kamoun Lab @ TSL, Loiret David
FOLD-RATE is a web server for predicting the folding rates of proteins from their amino acid sequences. The relationship between amino acid properties and protein folding rates has been systematically analyzed and a ...
Via Loiret David
Dr. Rommie Amaro, a computational and theoretical biophysical chemist in the McCammon Lab at UC San Dieo, studies infectious diseases such as ...youtube.com
Via Ramesh S Donadi, Loiret David
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interesting work