Genetic Mutations Warn of Skin Cancer Risk | Melanoma Dispatch | Scoop.it

"Researchers have discovered that mutations in a specific gene are responsible for a hereditary form of melanoma.


"Every year in the UK, almost 12,000 people are diagnosed with melanoma, a form of skin cancer. About 1 in 20 people with melanoma have a strong family history of the disease. In these patients, pinpointing the genetic mutations that drive disease development allows dermatologists to identify people who should be part of melanoma surveillance programmes.


"The team found that people with specific mutations in the POT1 gene were extremely likely to develop melanoma. These mutations deactivate the POT1 gene that protects the ends of our chromosomes from damage."