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Sentinel-Node Biopsy Improved DFS, Staging in Melanoma

Sentinel-Node Biopsy Improved DFS, Staging in Melanoma | Melanoma Dispatch | Scoop.it

Sentinel lymph node biopsy after wide excision improved DFS compared with wide excision alone among patients with intermediate and thick melanomas, according to final results of the MSLT-1 trial presented at the HemOnc Today Melanoma and Cutaneous Malignancies meeting in New York.


“ 'We found that performing sentinel lymph node biopsy is very accurate and improves staging in order to determine whether additional treatments are needed, such as additional surgery or adjuvant systemic therapy,' Robert H.I. Andtbacka, MD, CM, FACS, FRCSC, associate professor of surgery at Huntsman Cancer Institute at the University of Utah, said during a presentation. 'It also forms a basis for us to perform all the subsequent studies that we do in melanoma to make sure patients we have for our clinical trials are well balanced.' "


Editor's note: DFS stands for disease-free survival.

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Healio  |  Apr 15, 2014

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Long-Term Study Confirms Success of Method for Detecting Spread of Deadly Skin Cancer

Long-Term Study Confirms Success of Method for Detecting Spread of Deadly Skin Cancer | Melanoma Dispatch | Scoop.it

"Research at UCLA on a technique for detecting the earliest spread of melanoma, the deadliest form of skin cancer, has confirmed that the procedure significantly prolongs patients' survival rates compared with traditional "watch and wait" techniques.


"The technique, which combines lymphatic mapping and sentinel-node biopsy, allows doctors to quickly determine whether the disease has spread, or metastasized, to the lymph nodes, which occurs in approximately 20 percent of patients. Patients with cancer in their lymph nodes may benefit from having their other nearby lymph nodes removed. For the other approximately 80 percent of patients in whom the tumors have not spread to the lymph nodes, the technique spares the patient from unnecessary surgery and its associated complications and substantial costs."

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Medical Xpress  |  Mar 4, 2014

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