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New Treatment Proposed to Prevent Devastating Intestinal Inflammation in Cancer Patients

New Treatment Proposed to Prevent Devastating Intestinal Inflammation in Cancer Patients | Melanoma Dispatch | Scoop.it

"Experimental work pointing to a therapy for alleviating mucositis -- a common, severe side effect of chemotherapy and irradiation of cancer patients or patients prepared for bone marrow transplantation – has been achieved by an international team of researchers. Mucositis is a strong inflammatory reaction of the mucosal lining of the digestive system, particularly the gut. Mucositis is often a major reason for premature suspension of anti-cancer therapy. As of today, there has been no effective means of preventing mucositis or its treatment."

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ScienceDaily  |  Feb 18, 2014 

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Cancer Commons's curator insight, February 28, 2014 4:49 PM

ScienceDaily  |  Feb 18, 2014 

Cancer Commons's curator insight, February 28, 2014 4:51 PM

ScienceDaily  |  Feb 18, 2014 

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ACE Inhibitor Protects Heart and Lungs from Radiation Damage in Rats

Lung and breast cancers are often treated with radiation, but repeated high doses can also harm healthy tissues in the lungs and heart. New research suggests that both organs can be protected during radiation with a drug called captopril, an ACE inhibitor that is commonly used to treat cardiovascular disease. Radiation causes fibrosis (excess connective tissue) in the heart, diminishing blood flow to—and so damaging—the lungs. However, captopril decreases fibrosis in irradiated hearts and, therefore, also protects the lungs in rats, researchers reported at the European Society for Radiotherapy and Oncology's 2013 forum. The researchers are now designing a clinical trial to see if captopril also protects against radiation damage in people.

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Science Daily│Apr 21, 2013

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Cancer Commons's curator insight, April 23, 2013 1:18 PM

Science Daily│Apr 21, 2013

Cancer Commons's curator insight, April 23, 2013 1:18 PM

Science Daily│Apr 21, 2013

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Radiation Can Help Keep Desmoplastic Melanomas from Coming Back

Radiation Can Help Keep Desmoplastic Melanomas from Coming Back | Melanoma Dispatch | Scoop.it

Two new studies suggest that radiotherapy may help control a rare melanoma subtype that rarely spreads, but can recur locally. Called desmoplastic melanoma, this subtype often looks like tiny scars or dimples in the skin. The first study included 130 people with desmoplastic melanoma and found that this cancer came back three times as often in those who only had surgery than in those who also had radiation after surgery (24% vs 7%, respectively). The second study included 277 people with desmoplastic melanoma, and found that surgery failed to remove tumors completely in 35 of them. Of these 35 people, those who also had radiation after surgery were almost twice as likely to remain melanoma-free compared to those who only had surgery (86% vs 46%, respectively).

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HemOnc Today  |  Nov 18, 2013

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