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Melanoma Detection Enhanced with Blood Biomarkers

Melanoma Detection Enhanced with Blood Biomarkers | Melanoma Dispatch | Scoop.it

"The need for invasive skin biopsies could be reduced extensively with Edith Cowan University researchers working on ways to detect melanoma in early stages, using a blood test in conjunction with visual scans.


"A $450,000 National Health and Medical Research Council development grant has enabled them to expand on a 2012 preliminary investigation of 40 people that identified eight blood biomarkers that indicated the early presence of melanoma tumour.


"ECU School of Medical Sciences Professor Mel Ziman conducted the original investigation and is working with PhD student Pauline Zaenker and postdoctoral research fellow Dr Elin Gray on the latest study."

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Medical Xpress  |  May 13, 2014

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Quick, Simple Blood Test for Solid Cancers Looks Feasible

Quick, Simple Blood Test for Solid Cancers Looks Feasible | Melanoma Dispatch | Scoop.it

"The idea of a general, quick and simple blood test for a diverse range of cancers just came closer to reality with news of a new study published in Nature Medicine.


"Researchers from Stanford University School of Medicine have devised an ultra-sensitive method for finding DNA from cancertumors in the bloodstream.


"Previous research has already shown circulating tumor DNA holds promise as a biomarker for cancer, but existing methods for detecting it are not sufficiently sensitive and do not cover a diverse range of cancers.


"Ways to increase the sensitivity and coverage of such tests exist, but these are cumbersome and time-consuming, and need lots of steps to customize for individual patients, so they are not feasible for use in clinics.


"The new approach promises to change that. It is highly sensitive and specific and should be broadly applicable to a range of cancers, say the researchers."

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Medical News Today  |  Apr 7, 2014

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Medical News Today  |  Apr 7, 2014

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Medical News Today  |  Apr 7, 2014

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Sidestepping the Biopsy With New Tools to Spot Cancer

Sidestepping the Biopsy With New Tools to Spot Cancer | Melanoma Dispatch | Scoop.it

"For people with cancer or suspected cancer, the biopsy is a necessary evil — an uncomfortable and somewhat risky procedure to extract tissue for diagnosis or analysis.


"Lynn Lewis, a breast cancer patient in Brooklyn, has had her cancer analyzed an easier way: simple blood tests that are being called 'liquid biopsies.'


"Telltale traces of a tumor are often present in the blood. These traces — either intact cancer cells or fragments of tumor DNA — are present in minuscule amounts, but numerous companies are now coming to market with sophisticated tests that can detect and analyze them."

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The New York Times  |  Apr 7, 2014

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The New York Times  |  Apr 7, 2014

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The New York Times  |  Apr 7, 2014

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DNA Shed by Tumors Shows Promise for Non-Invasive Screening and Prognosis

DNA Shed by Tumors Shows Promise for Non-Invasive Screening and Prognosis | Melanoma Dispatch | Scoop.it

"Certain fragments of DNA shed by tumors into the bloodstream can potentially be used to non-invasively screen for early-stage cancers, monitor responses to treatment and help explain why some cancers are resistant to therapies, according to results of an international study led by Johns Hopkins Kimmel Cancer Center investigators.


"Analyzing blood samples from 640 patients with various cancers, the researchers used digital polymerase chain reaction-based technology (a sophisticated method of multiplying and measuring the number DNA molecules) to evaluate how well the DNA fragments predicted the presence of tumors in the patients."

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Medical Xpress  |  Mar 6, 2014

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Medical Xpress  |  Mar 6, 2014