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Experimental Drug Shows Early Promise for Some Cases of Advanced Melanoma

Experimental Drug Shows Early Promise for Some Cases of Advanced Melanoma | Melanoma Dispatch | Scoop.it

"An experimental cancer drug that activates the immune system has shown early promise for advanced cases of melanoma skin cancer, researchers report.


"The findings come from an early stage trial of just 31 patients. But experts were cautiously optimistic about what the study showed: The drug's side effects were manageable, and four patients saw their tumors shrink.


"That's a small number, but a trial like this is largely aimed at seeing whether a drug is safe and finding a tolerable dose."


Editor's note: This story is about a new melanoma drug called IMCgp100 that is being tested in patients. Learn more about immunotherapy drugs and clinical trials for melanoma here.

Cancer Commons's insight:

Medical Xpress  |  Apr 8, 2014

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New Melanoma Immunotherapy Advances in Early Trials

New Melanoma Immunotherapy Advances in Early Trials | Melanoma Dispatch | Scoop.it

On the strength of a promising phase I clinical trial, evaluations are continuing for an experimental immunotherapy that targets and selectively kills melanoma cells. Called IMCgp100, the drug has two parts that are fused together. One part is an immune system protein that has been engineered to recognize a protein called gp100, which is on the surface of melanoma cells. The other part of the new drug is a protein fragment that boosts the immune response against the tumor. The phase II trial of IMCgp100 is currently recruiting new participants.

Cancer Commons's insight:

Immunocore Limited│Oct 31, 2013

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