New Targetable Protein Linked to Melanoma Spread | Melanoma Dispatch | Scoop.it

New research suggests that melanomas are more likely to spread in people whose sentinel lymph nodes (SNLs) contain a particular subtype of white blood cells (lymphocytes). The researchers studied 42 people with melanoma, and found that tumors were more likely to spread within five years when their SNL lymphocytes had a surface protein called CD30. Moreover, this lymphocyte type was also more common in the blood of 25 people with advanced melanoma. These findings suggest that CD30 could be a target from treating melanoma, which is encouraging because the FDA has already approved a drug (brentuximab vedotin or Adcetris) that targets this protein for lymphoma treatment.