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Rescooped by Lisa Rhiannon Jeffers from Biochemistry
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How Exercise Changes Fat and Muscle Cells

How Exercise Changes Fat and Muscle Cells | Medicine | Scoop.it
Several striking new studies provide some clarity by showing that exercise seems able to drastically alter how genes operate, perhaps altering the risk for problems like obesity and diabetes.

Via Duncan Cole
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Duncan Cole's curator insight, October 1, 2013 9:15 AM

Interesting article reviewing research on how DNA methylation patterns are influenced by exercise.  Adaptations to exercise are not just related to alterations in the flux through metabolic pathways - they also involve epigenetic alterations that regulate expression of genes involved in these pathways.    

Rescooped by Lisa Rhiannon Jeffers from Biochemistry
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Cell Metabolism | Learn Science at Scitable

Cell Metabolism | Learn Science at Scitable | Medicine | Scoop.it
Cells constantly adjust the flow of molecules through metabolic pathways in response to energy needs. Learn how enzymes control these molecular transformations.

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Duncan Cole's curator insight, September 27, 2013 12:14 PM

This is an overview of metabolism from a cell biology perspective, and so will complement some of the whole organism and individual pathway perspectives found elsewhere.  The diagrams are particularly good, and the article is stated as at a Basic level within Nature's Scitable education site.  It isn't as clear as it could be in terms of structure however, but it does cover the major concepts. To get the most out of it you'll need to follow up the concepts highlighted in bold, as these are not eleaborated in any detail.

Rescooped by Lisa Rhiannon Jeffers from Biochemistry
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Overview of Metabolism - Anabolism and Catabolism

What is the purpose of metabolism? Learn about the two major divisions in metabolism: anabolism (building up) and catabolism (breaking down).

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Duncan Cole's curator insight, September 27, 2013 8:23 AM

If you are new to metabolism, or find it daunting and/or somewhat scary, this is a good place to start.  The broad concepts are outlined well and the explanations are good, with the meanings of key terms explained and not assumed. 

Rescooped by Lisa Rhiannon Jeffers from Biochemistry
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Cellular Respiration 1 - Overview

Cellular Respiration 1 - Overview | Medicine | Scoop.it

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Duncan Cole's curator insight, October 1, 2013 7:32 AM

This is the first in series of video tutorials in this excellent series from Handwritten Tutorials - the others can be all accessed from this webpage.  Each video has an accompanying completed diagram in pdf format which you can download.  Other tutorials in the series can be found on this scoop.it page, but all you really need is this link.

 

Rescooped by Lisa Rhiannon Jeffers from Digital-News on Scoop.it today
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Nobel Prize in Medicine Awarded for Cell Transport Discoveries

Nobel Prize in Medicine Awarded for Cell Transport Discoveries | Medicine | Scoop.it
Three scientists who helped undercover how the body's cells transport molecules to their correct locations have received this year's Nobel Prize in Physiology or Medicine.

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Rescooped by Lisa Rhiannon Jeffers from Biochemistry
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Metabolism - ChemWiki

Metabolism - ChemWiki | Medicine | Scoop.it

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Duncan Cole's curator insight, October 1, 2013 7:07 AM

Some good brief articles are available here on various metabolism topics from UC Davis in the USA.  I have spotted one or two mistakes, although these are not too serious, so be careful and check anything you are not sure about.

 

Rescooped by Lisa Rhiannon Jeffers from Biochemistry
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Cellular Respiration 4 - Beta-Oxidation

http://www.handwrittentutorials.com - This tutorial is the fourth in the Cellular Respiration series. This tutorial provides an overview of Beta-Oxidation, i...

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Duncan Cole's curator insight, October 1, 2013 7:19 AM

Nice tutorial on Beta-oxidation, although it goes into a little more detail than is required for a medical student.

Rescooped by Lisa Rhiannon Jeffers from Biochemistry
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Glycolysis: An Overview

NDSU VCell Production's animation "Glycolysis: An Overview". For more information please see http://vcell.ndsu.edu/animations. Glycolysis is a series of 10 r...

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Duncan Cole's curator insight, October 1, 2013 6:53 AM

An overview of glycolysis - contains some nice animations and helpful ways to visualise what is going on.  If you are just starting out learning metabolism you may need to pause frequently as the narration goes quite fast. 

 

If you follow the weblink above there are a number of other biochemistry-related videos/animations you may find helpful.

Rescooped by Lisa Rhiannon Jeffers from Biochemistry
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Exercise Physiology: musculoskeletal system

Exercise Physiology: musculoskeletal system | Medicine | Scoop.it
Exercise Physiology. Exercise represents one the highest levels of extreme stresses to which the body can be exposed.

Via Duncan Cole
Lisa Rhiannon Jeffers's insight:

Very good at explaining muscle contraction and where the ATP required for this process is from in a clear way. If you want the process written in bullet points for you this is a good document.

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Duncan Cole's curator insight, October 2, 2013 5:24 AM

This is a good description of the events that occur in the muscle during exercise, and will help provide context for those learning metabolism.  It has discussions on recovery and oxygen debt, fuel use during exercise, and does describe some of the interactions between metabolic pathways at different intensities of exercise.  There is also a description of the events involved in muscle contraction, and other pages discuss exercise-realted changes in other organ systems.

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Interaction among Skeletal Muscle Metabolic Energy Systems during Intense Exercise

Interaction among Skeletal Muscle Metabolic Energy Systems during Intense Exercise | Medicine | Scoop.it
Journal of Nutrition and Metabolism is a peer-reviewed, open access journal that publishes original research articles, review articles, and clinical studies in all areas of nutrition and metabolism.

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Duncan Cole's curator insight, October 2, 2013 6:38 AM

For those who want a little bit more detail...  this is a recent review focussing on the interaction of various energy systems during exercise.  It contains excellent figures and explains it all well, but only have a look beyond the abstract if you are reasonably familiar with metabolic pathways!