A new research report published in the Journal of Leukocyte Biology shows that compounds that stimulate the cannabinoid type 2 receptor in white blood cells, specifically macrophages, appear to weaken HIV-1 infection.
A much-maligned molecule that is devastating in the brain may have therapeutic potential outside it. The sticky amyloid-beta protein, which piles up in the brains of people with Alzheimer’s disease, actually reverses paralysis in mice with symptoms of multiple sclerosis...
In recent years, a small cadre of scientists has cautiously rekindled the scientific study of psychedelics.
“Now that we’ve been able to start getting some evidence on the benefits, it changes people’s calculus,” said Rick Doblin, the founder and executive director of the Multidisciplinary Association for Psychedelic Studies (MAPS), one of the meeting’s sponsors.
Doblin and MAPS have been battling regulators since the mid-80s to allow research and clinical trials with psychedelics. The recent revival of psychedelic science may be one sign their efforts are finally paying off.
Public attitudes towards illegal drugs in general may be shifting. A recent Pew Research Center survey, for example, found for the first time that more than half of Americans think marijuana should be legal. Baby boomers in particular, who may have hidden their stash while raising kids, seem to be loosening up in their old age, the survey found.
The interest in psychedelics may also have something to do with a growing sense of frustration over the lack of promising new psychiatric drugs in the pipeline. Many of the current drugs are based on compounds discovered serendipitously in the 1950s, and true innovation has been so hard to come by that many companies are giving up.
Meanwhile, people have been using hallucinogens for centuries, often in religious healing ceremonies, and yes, sometimes just for the hell of it. But just because they’re party drugs for some doesn’t mean they can’t be the subject of serious scientific inquiry. Or does it? After all, it didn’t end so well the first time around.
Few studies document short- and long-term pain and behavioral health in combat-injured service members with major limb trauma. In a 2-year longitudinal study, multiple post-injury pain and related outcomes are reported.
Smoking tobacco through a hookah is a pastime gaining popularity among the college crowd, but many of them mistakenly believe that using the fragrant water pipe is less harmful than smoking cigarettes.
Numerous studies have reported on pharmacogenetics of antidepressant response in depression. In contrast, little is known of response predictors in obsessive-compulsive disorder (OCD), a disorder with among the lowest proportion of responders to medication (40–60%)...
The tobacco and fruit mixture smoked in public hookah bars might be considerably more dangerous than its pleasant scent would suggest. An analysis of people who smoked from water pipes three times a day finds that the pipes deliver more carbon monoxide and benzene, a carcinogen, than does smoking half a pack of cigarettes daily....
It's late. I've got a lot on my plate. A lot to do. And most of us do. So here I am, burning the midnight oil along with many of my neighbors. I usually count myself lucky to get 7 hours a night, and I AM lucky. For many parents or other caregivers, for example, 7 hours is unheard-of luxury....
That South Park episode ring bells? Another green light folks, if the legislation hasn’t done enough. The only real medical trial testing THC like a treatment against cancer growth would be a certain British pilot study.
A range of diseases and conditions, from asthma to liver disease, could be diagnosed and monitored quickly and painlessly just by breathing, using gas sensing technology developed by a Cambridge spin-out.
The highly sensitive, low-power, low-cost infrared emitter developed by Cambridge CMOS Sensors (CCMOSS) is capable of identifying more than 35 biomarkers present in exhaled breath in concentrations as low as one part per million, and is being developed for use as a non-invasive medical testing device and other applications.
In addition to nitrogen, oxygen and carbon dioxide, we exhale thousands of chemical compounds with every breath: elevated acetone levels in the breath can indicate poorly-controlled diabetes, asthmatics will exhale higher than normal levels of nitric oxide, and glucose is a sign of kidney failure.
Throughout decades of research on solar cells, one formula has been considered an absolute limit to the efficiency of such devices in converting sunlight into electricity: Called the Shockley-Queisser efficiency limit, it posits that the ultimate...
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