Meded B12 Deficiency
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Genetic tests reveal need for vitamins

Genetic testing and a vitamin supplement helped dietitian Dr Sylvia Escott-Stump find a stable path for her son after he was diagnosed with schizophrenia.
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B12 Signs & Symptoms Assessment | B12 deficiency Support Group (Reg Charity 1146432)

B12 Signs & Symptoms Assessment | B12 deficiency Support Group (Reg Charity 1146432) | Meded B12 Deficiency | Scoop.it
The table below allows you to enter your signs and symptoms and immediately read off your B12 deficiency status (in the boxes at the start and end).
B12 unme's insight:

NHS GP, Dr Jo Chandy shares his five minute,  interactive, self-assessment tool for B12 Deficiency. Please do not suppliment B12 before you see your Dr as it may delay accurate diagnosis. 

http://www.b12d.org/b12-signs-symptoms-assessment


(Tool created by Hugo Minney Phd )


Dr Chandy's treatment protocol complied after more than 30 years of treating patients in the NHS for B12 Deficiency.

http://www.b12d.org/sites/default/files/PDF/B12_Deficiency_protocol_2011-05.pdf


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Medical Professionals - Pernicious Anaemia Society

Medical Professionals - Pernicious Anaemia Society | Meded B12 Deficiency | Scoop.it
Web site for Pernicious Anaemia Society
B12 unme's insight:

The PA Society has created a gateway for medical professionals on its homepage. http://www.pernicious-anaemia-society.org/medical_professionals


FAQs by medical professionals 

http://www.pernicious-anaemia-society.org/medical_professionals/faq ;

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Neuropsychiatric disorders caused by cobalamin ... [N Engl J Med. 1988] - PubMed - NCBI

PubMed comprises more than 23 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
B12 unme's insight:

"Among 141 consecutive patients with neuro-psychiatric abnormalities due to cobalamin deficiency, we found that 40 (28 percent) had no anemia or macrocytosis."

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Unbound MEDLINE : The pathophysiology of elevated vitamin B12 in clinical practic

Unbound MEDLINE : The pathophysiology of elevated vitamin B12 in clinical practic | Meded B12 Deficiency | Scoop.it
PubMed journal article The pathophysiology of elevated vitamin B12 in clinical practic was found in Unbound MEDLINE. Download PubMed App to iPhone, iPad, Android smartphone and tablet.
B12 unme's insight:

 Functional cobalamin deficiency can thus occur at any serum level.

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uknationalqualityassessmentschemeforhaematinicassays(1).pdf

B12 unme's insight:

Please also see Failure of Cobalamin Assays

http://www.nejm.org/doi/pdf/10.1056/NEJMc1204070

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Levodopa, vitamins, ageing and the neuropathy of Parkinson’s disease - Online First - Springer

Levodopa, vitamins, ageing and the neuropathy of Parkinson’s disease - Online First - Springer | Meded B12 Deficiency | Scoop.it
B12 unme's insight:

Researcher says give Parkinson's patients B12 and folate regardless of Levodopa treatment. http://link.springer.com/article/10.1007%2Fs00415-013-7079-8

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Biomarkers of cobalamin (vitamin B-12) status in the epidemiologic setting: a critical overview of context, applications, and performance characteristics of cobalamin, methylmalonic acid, and holot...

Biomarkers of cobalamin (vitamin B-12) status in the epidemiologic setting #b12 http://t.co/Z0lob2iSug
B12 unme's insight:

Really the only certain way of ruling out B12 Deficiency is to diagnose by signs & symptoms http://www.b12d.org/b12-signs-symptoms-assessment


The serum B12 misses up to 34% http://www.nejm.org/doi/pdf/10.1056/NEJMc1204070 ;

 

& NEQAS warns us the serum B12 is failing 

http://www.ukneqas-haematinics.org.uk/content/News.asp?id=40 

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A Review of the Current Methods for Diagnosing Vitamin B12 Deficiency in General and Pernicious Anaemia in Particular - Pernicious Anaemia Society

Web site for Pernicious Anaemia Society
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EVM0020P.pdf

B12 unme's insight:

See page 17 for reassurance about B12 toxicity 

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Society for Pediatric Urology - Long-term treatment outcomes of oral B12 supplementation in pediatric patients with B12 deficiency following ileal enterocystoplasty

Society for Pediatric Urology - Long-term treatment outcomes of oral B12 supplementation in pediatric patients with B12 deficiency following ileal enterocystoplasty | Meded B12 Deficiency | Scoop.it
B12 unme's insight:

Oral B12 has been shown to correct serum. Studies are needed to show Oral B12 protects and heals the nerves In the long term. http://www.ncbi.nlm.nih.gov/pubmed/23430814

 

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Vitamin B12 deficiency – time for a rethink?

Vitamin B12 deficiency – time for a rethink? | Meded B12 Deficiency | Scoop.it
Traditional view NHS Choices offers a traditional view of vitamin B12 metabolism and diagnosis and management of vitamin B12 deficiency anaemia. An up to date review was published recently link Vit...
B12 unme's insight:

In memory of NHS GP, Dr David Lewis, RIP, with gratefful thanks from the B12d patient community. 

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