"Are you looking for office space for lease in Evansville, Indiana? The 420 Main Street Building is a high-rise office structure and multi-level parking garage with160 feet of frontage on Main Street, and 141 feet of frontage on Fifth Street. It is located in Evansville's downtown business district at the west corner of S.E. 5th and Main Street. The 2nd through 5th floors have entries from the covered parking structure and direct elevator access on each level.