Macular Degeneration
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Alert! Oral Bisphosphonates Increase Risk Of Macular Degeneration

Alert! Oral Bisphosphonates Increase Risk Of Macular Degeneration | Macular Degeneration | Scoop.it
Today is World Osteoporosis Day, an awareness campaign organized by the International Osteoporosis Foundation (IOF) since 1997. This year’s campaign slog
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No Connection Seen Between Dementia, Common Eye Disease - MedicineNet

No Connection Seen Between Dementia, Common Eye Disease - MedicineNet | Macular Degeneration | Scoop.it
No link seems to exist between the common eye condition known as age-related macular degeneration and either dementia or Alzheimer's disease, a large new study shows.
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Gut microbes influence development of wet AMD

Gut microbes influence development of wet AMD | Macular Degeneration | Scoop.it
New mouse study finds an imbalance in gut microbes from high-fat diets influences evolution of wet AMD via increased gut permeability and inflammation.
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Maculas Affected by Age-Related Macular Degeneration Contain Increased Chelatable Iron in the Retinal Pigment Epithelium and Bruch's Membrane

Maculas Affected by Age-Related Macular Degeneration Contain Increased Chelatable Iron in the Retinal Pigment Epithelium and Bruch's Membrane | Macular Degeneration | Scoop.it
Research from JAMA Ophthalmology — Maculas Affected by Age-Related Macular Degeneration Contain Increased Chelatable Iron in the Retinal Pigment Epithelium and Bruch's Membrane
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The role of blue light in the pathogenesis of Age-related Macular Degeneration

The role of blue light in the pathogenesis of Age-related Macular Degeneration | Macular Degeneration | Scoop.it
Blue light exposure is one of the modifiable risk factors involved in the pathogenesis of Age-Related Macular Degeneration (AMD). Several studies have evaluated the relationship between light exposure and AMD, as well as clinical trials evaluated the visual function effect of blue filtering IOLs versus conventional IOLs. However, the authors encourage further clinical trials to assess the preventive filtering effect of ophthalmic lenses, particularly those with narrow bandwidth filters, in the development and/or progression of AMD.
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Home - Emerging Science in Advanced Age-related Macular Degeneration: Assessing New Evidence for Classification and Treatment

Home - Emerging Science in Advanced Age-related Macular Degeneration: Assessing New Evidence for Classification and Treatment | Macular Degeneration | Scoop.it
A CME-certified Activity titled Emerging Science in Advanced Age-related Macular Degeneration: Assessing New Evidence for Classification and Treatment
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Patients with AIDS at increased risk of developing age-related macular degeneration

Patients with AIDS at increased risk of developing age-related macular degeneration | Macular Degeneration | Scoop.it
New study results add to growing body of research that HIV-infected patients may experience age-related diseases earlier in life Patients with acquired immunodeficiency syndrome (AIDS) have a four-fold increase in their risk of developing...
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Stem Cell Treatment Used To Cure Age-Related Blindness

Stem Cell Treatment Used To Cure Age-Related Blindness | Macular Degeneration | Scoop.it
As one of the leading causes of vision loss, age-related macular degeneration (AMD) occurs due to the destruction of the part of the eye responsible for sh
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Homozygous YME1L1 mutation causes mitochondriopathy with optic atrophy and mitochondrial network fragmentation

Homozygous YME1L1 mutation causes mitochondriopathy with optic atrophy and mitochondrial network fragmentation | Mutations affecting a nuclear encoded metalloprotease cause of a new form of mitochondriopathy, highlighting the importance of this protease for mitochondrial function in humans.
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Choroidal neovascularisation on optical coherence tomography angiography in punctate inner choroidopathy and multifocal choroiditis. - PubMed - NCBI

Choroidal neovascularisation on optical coherence tomography angiography in punctate inner choroidopathy and multifocal choroiditis. - PubMed - NCBI | Macular Degeneration | Scoop.it
Br J Ophthalmol. 2016 Aug 18. pii: bjophthalmol-2016-308806. doi: 10.1136/bjophthalmol-2016-308806. [Epub ahead of print]
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Is it just 'getting old'? Gene causes hearing, sight loss and brittle bones in the elderly - Daily Express

Is it just 'getting old'? Gene causes hearing, sight loss and brittle bones in the elderly - Daily Express | Macular Degeneration | Scoop.it
“ A GENE that causes loss of hearing and eyesight and brittle bones in the elderly has been discovered.”
Via MRC press office
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MRC press office's curator insight, August 18, 6:28 AM
Researchers from MRC Harwell introduced new mutations at random positions in the genes of mice before they were born, and then monitored their health as they aged.
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Age-related macular degeneration may be triggered by tiny mineral deposits

Age-related macular degeneration may be triggered by tiny mineral deposits | Macular Degeneration | Scoop.it
New research from scientists at the University of Maryland School of Medicine (UM SOM) has found that tiny lumps of calcium phosphate may be an important triggering factor for age-related macular degeneration (AMD), a degenerative eye disease that can cause severe vision loss and blindness. This is the first time these mineral deposits have been implicated in the disease, which affects more than 10 million Americans. The article appeared in the latest issue of the Proceedings of the National Academy of Sciences. This is an image of HAP deposits, surrounded by fat and protein. The HAP is pink, while the surrounding material is green. Credit: UM SOM Biochemist Richard Thompson, PhD, along with his colleague from University College, London, Imre Lengyel, PhD, and a multidisciplinary international team studied retinal samples from a group of elderly patients, some of whom had AMD. They found that the AMD samples contained tiny spherules of a mineralized calcium phosphate known as hydroxyapatite, or HAP. HAP is common in the body - it comprises the hard part of bones and teeth - but it had never been identified in that part of the eye before. AMD develops slowly over decades, with the buildup of fatty protein deposits in the retina, which cause damage by blocking the flow of nutrients into the light-sensitive portion of the eye, and of waste products out. Scientists have known about these deposits for over a century, but their origins remained a mystery. Thompson and Lengyel discovered that the deposits appear to form around the tiny bits of HAP. Once these chunks appear, the fatty protein material coalesces around it; over years, these globules build up. They discovered the possible role of HAP by examining tissue samples from patients using X-ray diffraction and fluorescent staining chemicals.
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Eylea Side Effects, Cost, Dosage for Macular Degeneration and Diabetes Related Eye Conditions

Eylea Side Effects, Cost, Dosage for Macular Degeneration and Diabetes Related Eye Conditions | Macular Degeneration | Scoop.it
Eylea (aflibercept) side effects, cost, dosage and prescribing information for age-related macular degeneration (AMD), macular edema following retinal vein occlusion (RVO), diabetic macular edema (DME), and diabetic retinopathy (DR). Includes mechanism, dosing, efficacy, pregnancy, warnings, and financial assistance.
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Association of Lipids with Age-related Macular Degeneration - Junhui Shen - Discovery Medicine

Association of Lipids with Age-related Macular Degeneration - Junhui Shen - Discovery Medicine | Macular Degeneration | Scoop.it
In the past decades, much investigation has been done on the role of lipids in the development and progression of Age-related macular degeneration (AMD). The lipids involved in those research studies had included PUFAs, phospholipids, sphingolipids, cholesterol, lipid protein, etc. .
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MRC awards £4.3m to boost UK research base in dementia - News - Medical Research Council

MRC awards £4.3m to boost UK research base in dementia - News - Medical Research Council | Macular Degeneration | Scoop.it
MRC awards £4.3m to boost UK research base in dementia - Medical Research Council https://t.co/pAugRvsUmT
Via Krishan Maggon
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Imre Lengyel's curator insight, December 4, 1:04 PM
Proud to be the Ophthalmology Lead on this study!
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Alzheimer’s Proteins Could Be At Fault For Leading Cause of Vision Loss in Older People

Alzheimer’s Proteins Could Be At Fault For Leading Cause of Vision Loss in Older People | Macular Degeneration | Scoop.it
Neuroscience News has recent neuroscience research articles, brain research news, neurology studies and neuroscience resources for neuroscientists, students, and science fans and is always free to join.
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Nutrition's role in age-related macular degeneration - Mayo Clinic

Nutrition's role in age-related macular degeneration - Mayo Clinic | Macular Degeneration | Scoop.it
Increasing age and poor nutrition put you at risk for a type of vision loss called age-related macular degeneration. See how to reduce your risk.
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Macular Society’s call for more funding of research into macular degeneration

Macular Society’s call for more funding of research into macular degeneration | Macular Degeneration | Scoop.it
RT @cathyyelf: Macular Society’s call for more funding of research into macular degeneration https://t.co/ezLyxbn96v
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A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants

A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants | Macular Degeneration | Scoop.it
Advanced age-related macular degeneration (AMD) is the leading cause of blindness in the elderly with limited therapeutic options.
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Diet Improves Eyesight - Fitness Suppliments

Diet Improves Eyesight - Fitness Suppliments | Macular Degeneration | Scoop.it
What is the food that can really improve your eyesight? Many people suffer declining eyesight as they get older, but is there something we can eat to improve it, asks Michael Mosley. My eyesight has never been good. I’ve worn … Continue reading →
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Early Onset of Ocular Neovascularization After Hyperbaric Oxygen Therapy in a Patient With Central Retinal Artery Occlusion

Early Onset of Ocular Neovascularization After Hyperbaric Oxygen Therapy in a Patient With Central Retinal Artery Occlusion | Macular Degeneration | Scoop.it
Central retinal artery occlusion (CRAO) is an infarction to the retina that results in acute, frequently severe vision loss. Long-term complications such as ocular neovascularization (ONV) can occur a
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Can a simple supplement REALLY help you see better?

Can a simple supplement REALLY help you see better? | Macular Degeneration | Scoop.it
After discovering some ground-breaking research at the Nutrition Research Centre Ireland, the team of Trust Me, I'm A Doctor decided to have a trial of their own, which presented jaw-dropping results.
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New Treatment For Macular Degeneration

Implantable Miniature Telescope for macular degeneration Click for more information and a free informative eBook about low vision eyeglasses for macula
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New potential treatment for age-related macular degeneration offers hope to patients as phase III trials begin in Bristol, UK

Patients in Bristol suffering from geographic atrophy can now enroll in the phase III clinical program for lampalizumab, a drug being investigated for this form of age-related macular degeneration (AMD). GA is an advanced form of age-related macular degeneration (AMD), a progressive condition which can result in blindness, predominantly affecting people over the age of 70. There are more than 5 million people living with this debilitating condition worldwide and there are currently no approved treatments.1 The CHROMA and SPECTRI phase III clinical trials will evaluate the safety and efficacy and its potential to preserve visual function in people with GA.2 The studies will also further explore if people who have a specific genetic biomarker, complement factor I, may benefit more from the treatment than those who do not.
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New scientific solutions for exudative AMD when conventional treatments do not work - Institut de la Màcula

New scientific solutions for exudative AMD when conventional treatments do not work - Institut de la Màcula | Macular Degeneration | Scoop.it
New scientific solutions for exudative AMD when conventional treatments do not work
https://t.co/3X8RbLWIBs https://t.co/D4JpzBUTrG
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