About one-third of lung cancer patients treated with radiation therapy and chemotherapy experience recurrence at or near the original site. A study of patients with non-small cell lung cancer (NSCLC) or small-cell lung cancer (SCLC) investigated the use of renewed radiation ("reirradiation" or reRT) for such "locoregional recurrence." ReRT relieved symptoms in 75% of NSCLC patients and conferred long-term survival in some, especially those who had little functional impairment at the time of treatment and had received higher doses of radiation. Some SCLC patients whose returning cancer was small and did not cause symptoms, and whose cancer had not spread outside the chest region, also experienced increased survival from reRT. For all other SCLC patients, reRT produced no meaningful benefits.

Research paper: http://graphics.tx.ovid.com/ovftpdfs/FPDDNCMCHELLGK00/fs047/ovft/live/gv024/00000421/00000421-900000000-99449.pdf