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More than 130 Lawmakers Urge Coverage for Lung Cancer Test that Could Cost Medicare Billions

More than 130 Lawmakers Urge Coverage for Lung Cancer Test that Could Cost Medicare Billions | Lung Cancer Dispatch | Scoop.it

"More than 130 lawmakers are urging the Obama administration to expand coverage for a lung-cancer test under Medicare that could cost the program billons, calling the screening important for vulnerable seniors.

"In a letter to the Centers for Medicare and Medicaid Services, the lawmakers called for a timely decision on coverage for low-dose CT scans for older patients at higher risk of developing lung cancer."

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StarTribune  |  Jun 17, 2014

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Improved Diagnostic Performance of Low-Dose Computed Tomography Screening

Improved Diagnostic Performance of Low-Dose Computed Tomography Screening | Lung Cancer Dispatch | Scoop.it

"Investigators of the COSMOS (Continuous Observation of SMOking Subjects) study show good compliance and patient survival outcomes using a 5-year low-dose computed tomography (LDCT) screening protocol in individuals at high-risk of developing lung cancer. This protocol had fewer patients requiring further diagnostic follow-up compared to other studies, including the National Lung Cancer Screening Trial (NLST), with a minimal number of incorrect diagnoses."

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Medical Xpress  |  Jun 16, 2014

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Lung Cancer Screening Would Cost Medicare Billions

Lung Cancer Screening Would Cost Medicare Billions | Lung Cancer Dispatch | Scoop.it

"Implementation of a national lung cancer screening program using low-dose computed tomography (LDCT) will identify almost 55,000 additional lung cancer cases over 5 years, but will add more than $9 billion to Medicare expenditures, according to results of a new study.


"Joshua A. Roth, PhD, of the Fred Hutchinson Cancer Research Center in Seattle, discussed the economic analysis during a press conference in advance of the American Society of Clinical Oncology (ASCO) Annual Meeting, where results will be formally presented at the end of the month. He noted that following the positive results of the National Lung Screening Trial, the US Preventive Services Task Force recently recommended LDCT screening in healthy persons between the ages of 55 and 80 with at least 30 pack-years of smoking history. Medicare, meanwhile, is expected to release a draft decision on screening coverage in November of this year. 'That decision will likely heavily weight the Task Force’s recommendation,' Roth said."

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Cancer Network  |  May 15, 2014

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CT in Operating Room Allows More Precise Removal of Small Lung Cancers

CT in Operating Room Allows More Precise Removal of Small Lung Cancers | Lung Cancer Dispatch | Scoop.it

"A new technique that brings CT imaging into the operating room will allow surgeons to precisely demarcate and remove small sub-centimeter lung nodules, leaving as much healthy tissue as possible, according to a researcher. Lung cancer remains the deadliest cancer and a recent study indicated that screening with low-dose computed tomography (CT) scans in smokers, who have certain risk factors, may decrease the number of deaths. Lung cancer screening with CT can detect many small lung lesions that can potentially be cancerous and should be removed surgically."

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ScienceDaily  |  Apr 30, 2014

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MicroRNA Signature Classifier May Reduce False Positives in Lung Cancer

MicroRNA Signature Classifier May Reduce False Positives in Lung Cancer | Lung Cancer Dispatch | Scoop.it

"A noninvasive plasma microRNA signature classifier combined with low-dose CT was associated with a fivefold reduction in the false-positive rate for lung cancer detection compared with CT alone, according to results of a retrospective study.


"The analysis included 939 smokers enrolled in the Multicenter Italian Lung Detection trial who had been assigned low-dose CT (n=652) or observation (n=287)."


Editor's Note: Sometimes a doctor believes he/she has detected lung cancer in a patient, but the patient is later found not to have lung cancer. This is known as a "false positive." Scientists tested a new lung cancer detection procedure to see if it reduced the risk of false positives. The procedure combines CT scans with molecular testing of a patient's blood sample for substances that could indicate the presence of lung cancer. It found that the new procedure worked better than CT scans alone.

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Healio  |  Mar 19, 2014

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No Long-Term Anxiety or Distress Associated with Low-Dose Computed Tomography Screening

No Long-Term Anxiety or Distress Associated with Low-Dose Computed Tomography Screening | Lung Cancer Dispatch | Scoop.it

"Examination and review of several studies that evaluated patient-centered outcomes for individuals undergoing low-dose computed tomography (LDCT) screening for lung cancer found that screening does not appear to significantly influence overall health-related quality of life or result in long-term changes in anxiety or distress, but that positive results in the short-term, do increase distress levels."

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Medical Xpress  |  Jun 16, 2014

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The Ups and Downs of Lung Cancer Screening with Low-Dose CT

The Ups and Downs of Lung Cancer Screening with Low-Dose CT | Lung Cancer Dispatch | Scoop.it

"As a form of cancer that kills 90% of those who develop it, lung cancer is a particularly fearsome adversary to the field of oncology. However, because half of patients with lung cancer have advanced disease at the time of diagnosis, early detection offers hope for reduced mortality.


"To this end, several organizations — including the American Cancer Society (ACS), the National Comprehensive Cancer Network, the American Lung Association (ALA) and the US Preventive Services Task Force (USPSTF) — have updated their lung cancer screening guidelines to suggest screenings with low-dose CT."

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Healio  |  May 21, 2014

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CMS Advisory Panel Rejects Medicare Coverage for Lung Cancer Screening

CMS Advisory Panel Rejects Medicare Coverage for Lung Cancer Screening | Lung Cancer Dispatch | Scoop.it

"A CMS panel today rejected the concept of national Medicare coverage of annual lung cancer screening for high-risk individuals.


"The Medicare Evidence Development & Coverage Advisory Committee (MEDCAC) conducted a daylong hearing during which several clinicians and members of the public testified about the benefits and risks of lung cancer screening with low-dose CT."

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Healio  |  Apr 30, 2014

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ELCC 2014 News: Clinical Utility of miRNA Signature in Plasma of Smokers Included in LD-CT Lung Cancer Screening

"Recent results indicate that low-dose computed tomography (LD-CT) screening reduces lung cancer mortality in high risk subjects. However, high false positive rates, costs and potential harm highlight the need for complementary biomarkers. Led by Dr Ugo Pastorino, a group of researchers from Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy, retrospectively evaluated a non-invasive plasma miRNA signature classifier in prospectively collected samples from smokers within the randomised Multicentre Italian Lung Detection (MILD) trial. Their findings indicate that microRNA signature classifier has predictive, diagnostic and prognostic value and its combined use with LD-CT may improve screening performance. The results were presented in a proffered papers session at the 4th European Lung Cancer Conference (26-29 March 2014, Geneva, Switzerland)."


Editor's note: LD-CT is a lung cancer detection method that has been shown to reduce risk of death from lung cancer for high-risk patients. However, it sometimes leads to "false-positives," in which suspected cancer later turns out not to be cancer. A new, non-invasive blood test to look for specific kinds of miRNA molecules was shown to be promising as a potential companion test to complement LD-CT screening.

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ESMO  |  Mar 28, 2014

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