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A Wide Variety of Cancers Imaged and Treated with New Tumor-Targeting Agent

"Scientists at the University of Wisconsin Carbone Cancer Center (UWCCC) report that a new class of tumor-targeting agents can seek out and find dozens of solid tumors, even illuminating brain cancer stem cells that resist current treatments.


"What's more, years of animal studies and early human clinical trials show that this tumor-targeting, alkylphosphocholine (APC) molecule can deliver two types of 'payloads' directly to cancer cells: a radioactive or fluorescent imaging label, or a radioactive medicine that binds and kills cancer cells.


"The results are reported in today's issue of the journal Science Translational Medicine, and featured in the journal's cover illustration and podcast."


Editor's note: This story discusses a new method to make cancer cells visible to oncologists, and to deliver drugs directly to cells. The method uses a molecule called APC, which makes a beeline for cancer cells and can deliver imaging labels or radiotherapy treatments.

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Medical News Today  |  Jun 13, 2014

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Cancer Commons's curator insight, June 13, 2:29 PM

Medical News Today  |  Jun 13, 2014

Cancer Commons's curator insight, June 13, 2:29 PM

Medical News Today  |  Jun 13, 2014

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Preop PET Cuts Lung Cancer Surgery

Preop PET Cuts Lung Cancer Surgery | Lung Cancer Dispatch | Scoop.it

"Routine preoperative PET imaging led to a significant reduction in unnecessary surgery for non-small cell lung cancer (NSCLC), a review of almost 1,000 cases showed.


"Overall, the rate of unnecessary operations, defined as discovery of metastatic disease during surgery, decreased by 13%, which did not achieve statistical significance, according to Steven Zeliadt, PhD, of the Veterans Affairs Medical Center in Seattle, and co-authors. After adjustment for confounding factors, however, unnecessary operations occurred almost 50% less often with preoperative PET imaging."

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MedPage Today  |  Mar 7, 2014

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CT in Operating Room Allows More Precise Removal of Small Lung Cancers

CT in Operating Room Allows More Precise Removal of Small Lung Cancers | Lung Cancer Dispatch | Scoop.it

"A new technique that brings CT imaging into the operating room will allow surgeons to precisely demarcate and remove small sub-centimeter lung nodules, leaving as much healthy tissue as possible, according to a researcher. Lung cancer remains the deadliest cancer and a recent study indicated that screening with low-dose computed tomography (CT) scans in smokers, who have certain risk factors, may decrease the number of deaths. Lung cancer screening with CT can detect many small lung lesions that can potentially be cancerous and should be removed surgically."

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ScienceDaily  |  Apr 30, 2014

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Cancer Doctors Have Opportunities to Cut Costs Without Risk to Patients, Experts Say

Cancer Doctors Have Opportunities to Cut Costs Without Risk to Patients, Experts Say | Lung Cancer Dispatch | Scoop.it

"In a review article published Feb. 14 in The Lancet Oncology, Johns Hopkins experts identify three major sources of high cancer costs and argue that cancer doctors can likely reduce them without harm to patients. The cost-cutting proposals call for changes in routine clinical practice involved in end-of-life care, medical imaging and drug pricing.


" 'We need to find the best ways to manage costs effectively while maintaining the same, if not better, quality of life among our patients,' says Thomas Smith, M.D., The Harry J. Duffey Family Professor of Palliative Medicine and professor of oncology at Johns Hopkins."

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Medical Xpress  |  Feb 14, 2014

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Medical Xpress  |  Feb 14, 2014

Cancer Commons's curator insight, February 14, 1:29 PM

Medical Xpress  |  Feb 14, 2014