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New Clinical Guidelines for Cancer-Related Fatigue

New Clinical Guidelines for Cancer-Related Fatigue | Lung Cancer Dispatch | Scoop.it

"Fatigue is a debilitating problem for cancer patients undergoing treatment; however, it also poses a huge detriment after treatment and can significantly affect quality of life. Approximately 30 percent of cancer patients endure persistent fatigue for several years after treatment, according to an American Society of Clinical Oncology Expert Panel co-chaired by Paul Jacobsen, Ph.D., associate center director of Population Sciences at Moffitt Cancer Center."

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Medical News Today  |  Jun 3, 2014

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Medical News Today  |  Jun 3, 2014

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Medical News Today  |  Jun 3, 2014

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Modafinil Doesn't Improve NSCLC-Related Fatigue

Modafinil Doesn't Improve NSCLC-Related Fatigue | Lung Cancer Dispatch | Scoop.it

"The central nervous system stimulant modafinil is not effective in treating non-small-cell lung cancer-related fatigue, according to a study published online April 28 in the Journal of Clinical Oncology.


"Anna Spathis, M.B., B.Chir.,from Cambridge University Hospitals National Health Service Foundation Trust in the United Kingdom, and colleagues randomly assigned adults with advanced non-small-cell lung cancer, who were not treated with chemotherapy or radiotherapy within the last four weeks, to receive either daily modafinil (75 patients) or matched placebo (85 patients). Questionnaires were completed at baseline and day 28."

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Medical Xpress  |  Apr 30, 2014

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Steroid Treatment May Improve Cancer-Related Fatigue

Fatigue is a common and often debilitating symptom for people with advanced cancer. A recent clinical trial found that the steroid dexamethasone reduced fatigue in cancer patients who took it for 14 days. Other related symptoms, such as pain and loss of appetite, also improved, as did overall quality of life. However, in a recent survey, only one-quarter to one-third of cancer physicians said that they regularly use steroids to manage cancer-related fatigue. Because steroids can have serious side effects with long-term use, they may be most useful for patients with limited life expectancies or whose fatigue can be expected to resolve after short-term treatment.

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Medscape | Aug 2, 2013

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Medscape | Aug 2, 2013

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Worse Side Effects from Chemotherapy Experienced When Biological Rhythms Interrupted

"Patients receiving chemical treatment for cancer often suffer fatigue and body weight loss, two of the most worrying effects of this therapy linked to the alteration of their circadian rhythms.


"The circadian system, better known as our biological clock, is responsible for coordinating all the processes that take place in our organism.


"If it does not function correctly, what is known as a circadian disruption or chronodisruption, has for years been linked to an increased incidence of cancer, obesity, diabetes, depression, cognitive problems or cardiovascular diseases."


Editor's note: This research opens up the possibility of personalizing the timing of chemotherapy treatments to minimize side effects.

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Medical News Today  |  May 23, 2014

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Medical News Today  |  May 23, 2014

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Medical News Today  |  May 23, 2014

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ASCO Releases First Three Guidelines on Cancer Survivorship Care

"The American Society of Clinical Oncology (ASCO) today issued three evidence-based clinical practice guidelines on the prevention and management of symptoms that affect many cancer survivors—neuropathy, fatigue and depression, and anxiety. The guidelines are the first three in a planned series of guidelines on survivorship care. The recommendations reinforce the need to care for the both physical and psychological needs of cancer survivors."


"The release of these guidelines come at a time when the number of people with a history of cancer in the United States has increased dramatically, from 3 million in 1971 to about 13.7 million today. Despite these important gains, cancer survivors still face a range of long-term challenges from their disease and its treatment.  Cancer survivors face an increased risk for other health problems, premature mortality and side-effects from treatment.  The transition from active treatment to post-treatment care is critical to optimal long-term health. If care is not planned and coordinated, cancer survivors are left without knowledge of their heightened risks and a follow-up plan of action.


"In addition to the guidelines, Cancer.Net, ASCO’s patient information website, has updated information for survivors that is based on ASCO’s latest recommendations."

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ASCO  |  Apr 14, 2014

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ASCO  |  Apr 14, 2014

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ASCO  |  Apr 14, 2014

Tambre Leighn's curator insight, April 17, 11:30 AM

Great.  More guidelines.  How much money is spent on research, writing, studies and more to get to the finding that there is a, "need to care for the both physical and psychological needs of cancer survivors."  At some point, information must be turned into action - and many recommendations in survivorship these days come with mandates but no resources to implement or processes by which to initiate.


Cancer survivorship needs more funding and more insurance coverage, not more recommendations  - most of which have already been well documented and published for over a decade.  

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Exercise Increases Quality of Life for People with Cancer

Exercise Increases Quality of Life for People with Cancer | Lung Cancer Dispatch | Scoop.it

Cancer and its treatment can diminish quality of life, but two recent reviews of past clinical trials show that exercise can help restore a sense of well-being in both cancer patients and survivors. Measures of quality of life included fatigue, anxiety, and pain, while types of exercise included walking, bicycling, and yoga. The first review looked at 56 trials with a total of 4,826 people who were undergoing cancer treatment. This review showed, for example, that exercise reduced anxiety, fatigue, and sleep disturbances and that the more intense the exercise, the greater the benefits. The second review examined 40 trials with a total of 3,500 people who had completed cancer treatment. This review showed, for example, that people who exercised were less worried and felt less fatigue and pain. They also had better self images, which is key to avoiding the social isolation that can come with changes in appearance due to cancer treatments.

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Medical Xpress│Apr 5, 2013

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Medical Xpress│Apr 5, 2013