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Bronchial Gene Test Rules Out Lung Cancer

Bronchial Gene Test Rules Out Lung Cancer | Lung Cancer Dispatch | Scoop.it

"Gene analysis of the bronchial airway could reduce unnecessary invasive testing for suspected cases of lung cancer, a study suggested.


"A 17-gene test for normal epithelial cells gathered on bronchoscopy boosted the ability of that procedure to rule out cancer, Duncan Whitney, PhD, of test developer Allegro Diagnostics in Maynard, Mass., and colleagues found."

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MedPage Today  |  May 20, 2014

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Allegro Diagnostics Confirms Clinical Validation of BronchoGen™ Genomic Test for Improved Diagnosis of Lung Cancer in AEGIS-2 Clinical Trial

"Allegro Diagnostics Corp. today announced that the AEGIS-2 clinical trial has met its primary endpoint, demonstrating that the BronchoGen™ genomic test improves the accuracy of lung cancer diagnosis when used in combination with bronchoscopy. BronchoGen is Allegro Diagnostics’ lead genomic test, and it is built upon the company’s molecular testing platform that utilizes gene expression of cytologically normal epithelial cells in the respiratory tract to aid in the diagnosis of lung cancer. Endpoints in the clinical trial include the sensitivity, specificity and negative predictive value of BronchoGen for identifying patients with malignancy. Complete results from the clinical trial will be submitted for publication in a peer-reviewed journal."


Editor's note: Molecular testing of patients' tumor biopsies can be a powerful way to improve diagnosis and guide treatment decisions. Learn more about it.

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Business Wire  |  Apr 2, 2014

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