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Implementation of the NCI’s National Clinical Trials Network

Implementation of the NCI’s National Clinical Trials Network | Lung Cancer Dispatch | Scoop.it

"The National Cancer Institute is launching a new clinical trials research network intended to improve treatment for the more than 1.6 million Americans diagnosed with cancer each year.  The new system, NCI’s National Clinical Trials Network (NCTN), will facilitate the rapid initiation and completion of cancer clinical trials based on improvements in data management infrastructure, the development of a standardized process for prioritization of new studies, consolidation of its component research groups to improve efficiency, and the implementation of a unified system of research subject protection at over 3,000 clinical trials sites.  Grants to fund the program will be awarded early in the spring of 2014...


"NCTN employs an inclusive process for generating studies and conducting clinical trials using broad representation from the oncology field, including academic researchers, as well as professional organizations, patients, and advocates.  In particular, community-based clinical trials play an important role in expanding the implementation of research findings to encompass all phases of cancer care delivery.  A new system to support clinical trials research in the community setting, the NCI Community Oncology Research Program (NCORP), which will play a critical, complementary role to the NCTN, is being launched later this year and will involve both cancer treatment and cancer care delivery research."

Cancer Commons's insight:

National Cancer Institute  |  Mar 20, 2014

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Cancer Commons's curator insight, March 21, 3:54 PM

National Cancer Institute  |  Mar 20, 2014

Cancer Commons's curator insight, March 21, 3:54 PM

National Cancer Institute  |  Mar 20, 2014

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National Cancer Institute's 'RAS Project' Takes Aim at Common Cancer-Driving Protein

National Cancer Institute's 'RAS Project' Takes Aim at Common Cancer-Driving Protein | Lung Cancer Dispatch | Scoop.it

The National Cancer Institute (NCI) is organizing a massive collaborative initiative between its laboratory and hundreds of outside researchers to discover cancer treatments targeting a class of genes called RAS genes and their products, RAS proteins. RAS genes, including their most common form, KRAS, are mutated in one-third of all cancers. Although the important role of RAS in cancer has been known for over 30 years, no treatments targeting RAS have been developed so far, because RAS proteins lack a 'binding site' where drugs could attack. However, recent research has uncovered potential weaknesses in RAS that future treatment might exploit. The NCI's RAS Project aims to 'crowdsource' the expertise of many researchers to better understand and tackle RAS.

Cancer Commons's insight:

Science | June 24, 2013

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Cancer Commons's curator insight, June 26, 2013 1:19 PM

Science | June 24, 2013

Cancer Commons's curator insight, June 26, 2013 1:19 PM

Science | June 24, 2013

Cancer Commons's curator insight, June 26, 2013 1:19 PM

Science | June 24, 2013