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How Machine Learning and Big Data Are Changing the Face of Biological Sciences

Until recently, the wet lab has been a crucial component of every biologist. Today's advances in the production of massive amounts of data and the creation of machine-learning algorithms for processing that data are changing the face of biological science—making it possible to do real science without a wet lab. David Heckerman shares several examples of how this transformation in the area of genomics is changing the pace of scientific breakthroughs.


Via Szabolcs Kósa
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davidgibson's curator insight, May 28, 2013 11:05 PM

This 36 min video is well worth the time spent - to get an idea (hopefully a transferrable one) about Big Data and the frontiers of science. In this case both "wet lab" (test tubes microscopes) and "dry lab" (computer modeling with machine learning) and needed and so is content as well as computational literacy.

Serena Fuchs's curator insight, June 26, 2013 3:43 PM

The low-hanging fruit, SNPs, have been picked off.  Now much research is using larger data sets to look for significant variants, and the compute power needed can increase exponentially. Look to dog breeders as the pioneers of controlling for known variables to reduce the false positive results. 

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Artificial jellyfish created from rat heart tissue and silicone

Artificial jellyfish created from rat heart tissue and silicone | Longevity science | Scoop.it

Researchers at Harvard University and the California Institute of Technology (Caltech) looking to gain a better understanding of how biological pumps such as the heart work, have created an artificial jellyfish from rat heart muscle and silicon.

 

This is just neat biological science...

 

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Awesome Video Explains Synthetic Biology | Singularity Hub

Awesome Video Explains Synthetic Biology | Singularity Hub | Longevity science | Scoop.it

"A succinct, yet powerful animation titled “Synthetic Biology Explained” shows the incredible potential of this emergent field and how engineering will transform the field of genetics to produce some truly amazing technology.

 

With the sequencing of the human genome and the increased understanding of genes that have followed..."

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Unscientific America—Denying Science at Our Peril

Unscientific America—Denying Science at Our Peril | Longevity science | Scoop.it

Is policy behind science?

This opinion piece explores politics and their potential limitations on science-based change.

 

“Increasingly, scientific consensus is failing to influence public policy. Facts, statistics and data appear insufficient to change highly politicized minds… and science has started scrutinizing why.

 

Alas now, this topic inevitably devolves down to our screwy American politics….”

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Kayhla Cornell's curator insight, February 28, 11:56 AM

Policy and Science. 

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All genomes are dysfunctional: broken genes in healthy individuals

All genomes are dysfunctional: broken genes in healthy individuals | Longevity science | Scoop.it

Genome-sequencing studies indicate that all humans carry many genetic variants predicted to cause loss of function (LoF) of protein-coding genes, suggesting unexpected redundancy in the human genome. It is estimated that human genomes typically contain ~100 genuine LoF variants with ~20 genes completely inactivated. A recent paper in Science describes some of these rare and likely deleterious LoF alleles, including 26 known and 21 predicted severe disease–causing variants, as well as common LoF variants in nonessential genes.


Via Dr. Stefan Gruenwald
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20,000+ FREE Online Science and Technology Lectures from Top Universities

20,000+ FREE Online Science and Technology Lectures from Top Universities | Longevity science | Scoop.it

The following topics are covered:

 

Aerospace, Anthropology, Astrobiology, Astronomy, Astrophysics, Biochemistry, Bioengineering, Biology, Biotechnology, Chemistry, Civil Engineering, Cognitive Science, Computers, Cosmology, Dentistry, Electrical Engineering, Engineering, Environment, Future, General Science, Geoscience, Machine Learning, Material Science, Mathematics, Mechanical Engineering, Medicine, Metallurgy, Mining, Nanotechnology, Oceanography, Philosophy, Physics, Physiology, Robotics, and Sociology.

 

Lectures are in Playlists and are alphabetically sorted with thumbnail pictures. No fee, no registration required - learn at your own pace. Certificates can be arranged with presenting universities.


Via Dr. Stefan Gruenwald
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Casper Pieters's curator insight, March 9, 7:21 PM

Great resources for online learning just about everything.  All you need is will power and self- discipline.

Russ Roberts's curator insight, April 23, 11:37 PM

A very interesting site.  Amazing Science covers many disciplines.  Subscribe to the news letter and be " amazed." Aloha, Russ, KH6JRM. 

Siegfried Holle's curator insight, July 4, 8:45 AM

Your knowledge is your strength and power 

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First complete computer model of an organism | KurzweilAI

First complete computer model of an organism | KurzweilAI | Longevity science | Scoop.it

A team led by Stanford bioengineering Professor Markus Covert used data from more than 900 scientific papers to account for every molecular interaction that takes place in the life cycle of Mycoplasma genitalium — the world’s smallest free-living bacterium.

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Accelerated Tech News– Implants, Scanners, and More

Accelerated Tech News– Implants, Scanners, and More | Longevity science | Scoop.it

Have you watched the accelerated tech news? It's a quick and easy way to get tech news into your head.

 

This edition:

iPads as a medical manager, retinal implants and more: video tech news

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Why Outsourcing Science May Be The Best Hope for Its Future | Singularity Hub

Why Outsourcing Science May Be The Best Hope for Its Future | Singularity Hub | Longevity science | Scoop.it

Could Science Exchange become the Ebay of scientific research? This new marketplace helps to accelerate scientific studies by supporting collaboration and allowing researchers to share, buy and sell resources.

 

They vet providers, handle the monetary transactions, curate a rating system for each provider (and researcher), help providers publicize availability, and can sometimes track down exact providers...

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