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New Study Validates Longevity Pathway | Resveratrol and Longevity

New Study Validates Longevity Pathway | Resveratrol and Longevity | Longevity science | Scoop.it

A new study demonstrates what researchers consider conclusive evidence that the red wine compound resveratrol directly activates a protein that promotes health and longevity in animal models.

 

What’s more, the researchers have uncovered the molecular mechanism for this interaction, and show that a class of more potent drugs currently in clinical trials act in a similar fashion. Pharmaceutical compounds similar to resveratrol may potentially treat and prevent diseases related to aging in people, the authors contend.

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Re-forming resveratrol: Bioavailability issues are no more as researchers reveal metabolites regenerate

Re-forming resveratrol: Bioavailability issues are no more as researchers reveal metabolites regenerate | Longevity science | Scoop.it
Metabolites from the break-down of resveratrol have been shown to come together and regenerate the compound inside living cells, leaving researchers questioning whether worries over bioavailability are relevant.
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New evidence on how compound found in red wine can help prevent cancer | KurzweilAI

New evidence on how compound found in red wine can help prevent cancer | KurzweilAI | Longevity science | Scoop.it

University of Leicester scientists have presented groundbreaking new evidence about how a chemical found in red wine can help prevent cancer.

 

Experts from around the world attended Resveratrol 2012, a major conference at the University to assess the latest advances in the study of resveratrol — a compound found in the skins of red grapes.

 

 

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Resveratrol study results don’t tell the whole story on benefits: Expert

A new study that concluded resveratrol does not have metabolic benefits in relatively healthy middle-aged women is "flawed" and "tells us very little about the benefits or non-benefits of resveratrol", says the chairman of GNC’s Medical Advisor Board.

 

It was a very small study. Only 15 women were treated with resveratrol. These women were already quite healthy and lean.

 

The dose used was small. At only 75mg per day, this amount is less than most recommendations and earlier animal studies indicate for benefits.

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Effects of red wine polyphenols and alcohol on glucose metabolism and the lipid profile: A randomized clinical trial

Study supports a beneficial effect of the non-alcoholic fraction of red wine (mainly polyphenols) on insulin resistance, conferring greater protective effects on cardiovascular disease to red wine than other alcoholic beverages.

 

(ref) Clinical Nutrition, Volume null, Issue null, Pages null, null, Authors:Gemma Chiva-Blanch; Mireia Urpi-Sarda; Emilio Ros; Palmira Valderas-Martinez; Rosa Casas; Sara Arranz; Marisa Guillén; Rosa M.

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Controversial Anti-Aging Chemical Resveratrol Back In The Spotlight With New Details About How It Works

Controversial Anti-Aging Chemical Resveratrol Back In The Spotlight With New Details About How It Works | Longevity science | Scoop.it

Resveratrol, the famed anti-aging supplement extracted from red wine, has experienced its share of controversy.

 

An experimental artifact, a pair of studies that questioned its health benefits, and the shady practices of one now-discredited scientist have put resveratrol in a bad light as of late.

 

But a recent study now attempts to help set the record straight by confirming one part of the resveratrol puzzle…

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Wine Associated with Improved Lung Function

Wine Associated with Improved Lung Function | Longevity science | Scoop.it

A recent study supported existing research that moderate wine intake supports healthy lung function. The researchers found an association between resveratrol intake and higher lung volumes, as well as white wine intake and lower risk of airway obstruction.

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Resveratrol may help to protect against alcohol induced nerve damage, suggest researchers

Resveratrol may help to protect against alcohol induced nerve damage, suggest researchers | Longevity science | Scoop.it
Resveratrol could help to battle diseases characterised by damaged to nerve cells from alcohol, according to new lab findings.
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Red Wine and Cancer Prevention - National Cancer Institute

>> Research on the antioxidants found in red wine has shown that they may help inhibit the development of certain cancers (see Question 1).
>>Resveratrol has been shown to reduce tumor incidence in animals by affecting one or more stages of cancer development. It has been shown to inhibit growth of many types of cancer cells in culture (see Question 2).
>>Evidence from animal studies suggests this anti-inflammatory compound may be an effective chemopreventive agent in three stages of the cancer process: Initiation, promotion, and progression (see Question 3).
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There is a long standing body of research indicating that resveratrol and other polyphenols can help maintain healthy cellular activity, discouraging certain types of cancer.

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TACT: Chelation regimen reduced adverse events in post-MI patients | Cardiology

TACT: Chelation regimen reduced adverse events in post-MI patients | Cardiology | Longevity science | Scoop.it

Cardiology | LOS ANGELES — Patients with a prior MI given weekly infusions of chelation therapy experienced fewer CV events than patients who received placebo infusions, according to new results from the TACT trial.

 

 

Dr. Terry Grossman discusses:

 

Conventional medicine does not typically support chelation as a treatment for heart disease saying there is no good evidence that it works.

 

The results of the TACT (Trial to assess Chelation Therapy) are in.

 

The results were presented at the AHA (American Heart Association) meeting yesterday. 

 

This was the first well designed, randomized, double-blind, placebo-controlled trial of chelation therapy EVER and it showed that EDTA chelation therapy resulted in fewer cardiovascular events than placebo – particularly for diabetics.

 

The major benefits were in the reduction of revascularization procedures, likes stents and bypass surgery.

 

The 1/3 of subjects who were diabetic had a hazards ratio of 0.61. so diabetic subjects were 39% less likely to need stenting or bypass if they got chelation than if they got placebo, with a p value of 0.002 (this means a 2 in 1000 probability these results were due to chance).

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Red wine compound backed to extend life and reduce food intake ... in bees

Red wine compound backed to extend life and reduce food intake ... in bees | Longevity science | Scoop.it
The red wine compound resveratrol could help to extend life and may even help to battle obesity by 'moderating' food consumption, according to new research ... in bees.

 

The findings showed that bees given resveratrol consumed less food and lived up to 38% longer.

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Resveratrol may improve mobility in older subjects: Animal data

Resveratrol may improve mobility in older subjects: Animal data | Longevity science | Scoop.it
The red wine compound resveratrol could help older people to battle against motor deficiencies that lead to mobility problems and increased risks of falls, according to new research in mice.

 

The older mice in the study received resveratrol for  weeks. By the fourth week, these mice had improved mobility, on par with the younger mice.

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Delaying Fat Cell Growth

Delaying Fat Cell Growth | Longevity science | Scoop.it

Researchers from Purdue University in Indiana are testing a compound found in red wine that has the ability to block the processes of fat cell development. The research into the compound known as piceatannol may lead towards finding a simple method to combat obesity.

 

Piceatannol results from the conversion of resveratrol – a compound found in red wine, grapes and peanuts that is also thought to combat cancer, heart disease and neurodegenerative diseases. When resveratrol is converted into the piceatannol

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Study Uncovers Resveratrol’s Probable Mechanism Of Action - Nutraceuticals World

Study Uncovers Resveratrol’s Probable Mechanism Of Action - Nutraceuticals World | Longevity science | Scoop.it

Resveratrol, how does it work? Unlike previously thought, it does not directly activate sirtuin 1 (protein associated with aging). Instead, it may inhibit other enzymes that help regulate cell energy.

 

"National Institutes of Health researchers and their colleagues have identified how resveratrol, a naturally occurring chemical found in red wine and other plant products, may confer its health benefits."

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