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Berkeley researchers find evidence for a "molecular fountain of youth"

Berkeley researchers find evidence for a "molecular fountain of youth" | Longevity science | Scoop.it

 

A group of medical researchers at the University of California at Berkeley has found a protein that is able to rejuvenate aged blood stem cells...

 

The ravages of aging appear to be related to oxidative stress combined with telomere exhaustion, along with many other known and unknown factors. The subject of the new Berkeley study is a class of proteins called sirtuins that are known to play a central role in regulating aging and longevity in many non-human models (such as mice).

 

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Merridee Wouters's curator insight, March 28, 2013 12:03 PM

Relevant pathophysiology

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‘Fountain of youth’ technique rejuvenates aging stem cells | KurzweilAI

‘Fountain of youth’ technique rejuvenates aging stem cells | KurzweilAI | Longevity science | Scoop.it

A new method of growing cardiac tissue is teaching old stem cells new tricks.

The discovery, which transforms aged stem cells into cells that function like much younger ones, may one day enable scientists to grow cardiac patches for damaged or diseased hearts from a patient’s own stem cells — no matter what age the patient — while avoiding the threat of rejection.

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Hydra's immortality gene sheds light on human ageing

Hydra's immortality gene sheds light on human ageing | Longevity science | Scoop.it

The tiny freshwater polyp Hydra is a remarkable creature. It does not show any signs of ageing and appears to be immortal. Researchers from Kiel University have examined this phenomenon and uncovered an important link to the ageing process in humans that could lead to the development of advanced rejuvenation therapies.

 

How does the polyp Hydra do this? It accomplishes the feat of apparent immorality by reproducing through budding rather than mating. Each polyp contains stem cells capable of continuous proliferation. Without this endless supply of regenerating stem cells, the animals could not reproduce.

 

 

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The Future is Now-- SENS Foundation Report

SENS Foundation (which “works to develop, promote and ensure widespread access to rejuvenation biotechnologies which comprehensively address the disabilities and diseases of aging.”)
need “no longer discuss and emphasize what the future might hold.

 

Rather, [they] discuss and emphasize what is going on right now at the SENS Foundation Research Center in Mountain View, California, and in Foundation-funded laboratories across the world:

 

Research to counteract arteriosclerotic plaque, DNA damage and other causes of aging, as well as developments to make new limbs and initiatives to sponsor young scientists.

 

(link opens pdf of 2011 Annual Report)

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