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Weight Loss Doesn't Help Heart Health For Diabetics In Study : NPR

Weight Loss Doesn't Help Heart Health For Diabetics In Study : NPR | Longevity science | Scoop.it
Researchers were surprised to find that people with Type 2 diabetes who lost a lot of weight didn't lower their risk of heart attacks or strokes. They did have better control of their blood sugar and saw other health benefits.
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Potential diabetes breakthrough | KurzweilAI

Potential diabetes breakthrough | KurzweilAI | Longevity science | Scoop.it

Researchers at the Harvard Stem Cell Institute (HSCI) have discovered a hormone that holds promise for a dramatically more effective treatment of type 2 diabetes, a metabolic illness afflicting an estimated 26 million Americans.

The researchers believe that the hormone might also have a role in treating type 1, or juvenile, diabetes.

 

 

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Scientists use gene therapy to cure dogs of type 1 diabetes

Scientists use gene therapy to cure dogs of type 1 diabetes | Longevity science | Scoop.it

Researchers from the Universitat Autònoma de Barcelona (UAB) have claimed a first by successfully using a single session of gene therapy to cure dogs of type 1 diabetes. The work has shown that it is possible to cure the disease in large animals with a minimally-invasive procedure – potentially leading the way to further developments in studies for human treatment of the disease.

 

 

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Artificial pancreas and algorithm improve treatment for type 1 diabetes | KurzweilAI

Artificial pancreas and algorithm improve treatment for type 1 diabetes | KurzweilAI | Longevity science | Scoop.it

The first trial comparing a new dual-hormone “artificial pancreas” with conventional diabetes treatment using an insulin pump has been completed by researchers at IRCM (Institut de Recherches Cliniques) of Montreal, led by endocrinologist Dr. Rémi Rabasa-Lhoret. It showed improved glucose levels and lower risks of hypoglycemia.

 

 

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Diabetes may be linked to hearing loss: study

Diabetes has already been tied to an increased risk of kidney and cardiovascular troubles, nerve damage and vision loss, and now a Japanese study finds diabetics to be more than twice as likely as those without the disease to have hearing impairment.

 

It's thought that high blood sugar levels brought on by diabetes may lead to hearing loss by damaging blood vessels in the ears, said Horikawa.

 

 

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Vitamin D backed to boost diabetic heart disease risk

Vitamin D backed to boost diabetic heart disease risk | Longevity science | Scoop.it

Low levels of vitamin D may be responsible for the increased risk of heart disease that comes from diabetic people developing clogged up arteries, according to new research.

 

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TACT: Chelation regimen reduced adverse events in post-MI patients | Cardiology

TACT: Chelation regimen reduced adverse events in post-MI patients | Cardiology | Longevity science | Scoop.it

Cardiology | LOS ANGELES — Patients with a prior MI given weekly infusions of chelation therapy experienced fewer CV events than patients who received placebo infusions, according to new results from the TACT trial.

 

 

Dr. Terry Grossman discusses:

 

Conventional medicine does not typically support chelation as a treatment for heart disease saying there is no good evidence that it works.

 

The results of the TACT (Trial to assess Chelation Therapy) are in.

 

The results were presented at the AHA (American Heart Association) meeting yesterday. 

 

This was the first well designed, randomized, double-blind, placebo-controlled trial of chelation therapy EVER and it showed that EDTA chelation therapy resulted in fewer cardiovascular events than placebo – particularly for diabetics.

 

The major benefits were in the reduction of revascularization procedures, likes stents and bypass surgery.

 

The 1/3 of subjects who were diabetic had a hazards ratio of 0.61. so diabetic subjects were 39% less likely to need stenting or bypass if they got chelation than if they got placebo, with a p value of 0.002 (this means a 2 in 1000 probability these results were due to chance).

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Beans show promise in diabetes

Beans show promise in diabetes | Longevity science | Scoop.it

NEW YORK (Reuters Health) - Downing a cup of beans or lentils every day may help people with type 2 diabetes control their blood sugar and possibly reduce their risk of heart attacks and stroke, according to a small study.

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Scientists announce new treatment for type II diabetes

Scientists announce new treatment for type II diabetes | Longevity science | Scoop.it
Scientists have announced a new method of treating and preventing type II diabetes.

 

The new treatment focuses on VEGF-B, a protein within the body that affects how fat is transported and stored. Using an antibody/drug known as 2H10, the scientists were able to block the signaling of VEGF-B in mice and rats, which subsequently kept fat from accumulating in the “wrong” areas of the animals – namely their muscles, blood vessels and hearts.

 

The paper for this researched was published in Nature on Sept 26:

http://www.nature.com/nature/journal/vaop/ncurrent/full/nature11464.html

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Protein that boosts longevity may protect against diabetes

Protein that boosts longevity may protect against diabetes | Longevity science | Scoop.it

SIRT1, a protein that slows aging in mice and other animals, also protects against the ravages of a high-fat diet, including diabetes, according to a new MIT study.

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Steve Kingsley's curator insight, October 12, 2013 7:24 PM

Somehow I thought high carb - especially refined sugar - diet was the main culprit in developing diabetes. 

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Chemical that slows down the biological clock could lead to new drugs to treat diabetes

Chemical that slows down the biological clock could lead to new drugs to treat diabetes | Longevity science | Scoop.it

Scientists have long suspected that metabolic disorders, such as type 2 diabetes and obesity, could be linked to our circadian rhythm or biological clock. For example, laboratory mice with altered biological clocks often become obese and develop diabetes.

 

Now biologists at UC San Diego have discovered that a chemical, which affects the activity of a key protein that regulates our biological clock, can repress the production of glucose by the liver, offering a promising new direction for the development of a new class of drugs to treat diabetes.

 

A team headed by Steve Kay, dean of the Division of Biological Sciences at UC San Diego, had previously found that altering the levels of a key protein, called cryptochrome – which regulates the biological clocks of plants, insects and mammals and also regulates glucose production in the liver – could improve the health of diabetic mice.

 

Building on that research...

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Rethinking G20: SESIÓN 2: PROVOCAR EL SIGNIFICADO

Dr. Terry Grossman presented at the G20: Designing the Future conference in Mexico. His portion begins at about 1:22:46 and runs 12 minutes.


(G20: SESIÓN 2: PROVOCAR EL SIGNIFICADO)

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Anti-Inflammatory Drug with a New Benefit to Glucose

In a modern-day clinical trial of a medicine belonging to one of the world's oldest classes of drugs, researchers have found that a drug related to aspirin and salicylate, which was first used by ancient Egyptians and Greeks to ease pain caused by inflammation, also has glucose-lowering properties and may be a potential treatment for people with type 2 diabetes, according to results presented at the American Diabetes Association's 72nd Scientific Sessions(R).

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Injectable nanoparticles maintain normal blood-sugar levels for up to 10 days

Injectable nanoparticles maintain normal blood-sugar levels for up to 10 days | Longevity science | Scoop.it
A newly developed network of nanoscale particles can maintain normal blood sugar levels for more than a week by releasing insulin when blood-sugar levels rise.

 

This system could help type I diabetics replace insulin injections and monitoring.

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Mixed results on computer-based support for diabetes

Computer and mobile phone programs that provide tailored advice and support to people with diabetes may not do much to improve their health and quality of life, a new report suggests.

 

 

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Mediterranean diet may be best for diabetes

Diets lean on meat and rich in healthy fats like olive oil were most effective at promoting weight loss and lowering blood sugar among people with diabetes in a review of evidence from the last 10 years.

Benefits were also seen with diets low in carbohydrates, high in protein or low in simple sugars.

 

 

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Steve Kingsley's curator insight, June 2, 2013 1:32 PM

It certainly is the healthiest!

Steve Kingsley's curator insight, June 2, 2013 1:33 PM

It certainly is the healthiest!

Vincent D'Antonio's curator insight, June 10, 2013 9:09 AM

Diet based on a healthy region of the world.

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Insulin “docking“ breakthrough could lead to better diabetes treatments

Insulin “docking“ breakthrough could lead to better diabetes treatments | Longevity science | Scoop.it

Despite decades of study, scientists remained unsure as to how insulin binds to the insulin receptor on the surface of cells to allow them to take up sugar from the blood and transform it into energy.

 

Now, a definitive answer has now been found with a team of scientists capturing the first three-dimensional images of insulin “docking” to its receptor.

 

It is hoped that the new knowledge can be exploited to develop new and improved insulin medications to treat type 1 and type 2 diabetes.

 

 

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Caffeine-diabetes link still unresolved: study

Results of a large new U.S. study confirm that sugary drinks are linked to a heightened risk of developing Type 2 diabetes, but shed little light on whether caffeine helps or hinders the process.

 

Among more than 100,000 men and women followed for 22 years, those who drank sugar-sweetened drinks were as much as 23 percent more likely to develop diabetes than those who didn't, but the risk was about the same whether the drinks contained caffeine or not.

 

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Diabetes cases hit record and half go undiagnosed

The number of people living with diabetes is now put at 371 million, up from 366 million a year ago, with numbers expected to reach 552 million by 2030, the International Diabetes Federation (IDF) said.

 

Diabetes is often viewed as a western problem, since the vast majority of people have type 2 disease which is linked to obesity and lack of exercise.

 

 

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Trans fats raise cholesterol, not blood sugar: study

(Reuters) - Although much-criticized trans fats raise levels of "bad" cholesterol, they don't appear to have a lasting impact on blood sugar levels, according to a U.S. study.

 

Researchers, writing in The American Journal of Clinical Nutrition, found that both blood sugar and insulin, the hormone that keeps blood sugar levels in check, were similar regardless of how much trans fat people ate.

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Vitamin K may slash diabetes risk: Study

Increased intakes of vitamin K1 may lower the risk of developing type-2 diabetes in elderly people with a high risk of cardiovascular disease, says a new study.

 

There is an irony in these results. Most people over the age of 60 with a risk of cardiovascular disease (and virtually all people over 75) are prescribed warfarin, a blood thinning medication.

 

Vitamin K contributes to clotting. In patients on warfarin, Vitamin K intake is discouraged to make it easier to regulate medication levels and maintain a proper blood flow.

 

Vitamin K is found in many vegetables with additional health properties such as broccoli and leafy greens. If an increase in this vitamin could help lower the risk of diabetes, some patients may have to make a decision whether they can properly regulate their levels on warfarin.

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Curcuminoids exert glucose-lowering effect in type 2 diabetes by decreasing serum free fatty acids: a double-blind, placebo-controlled trial - Na - 2012 - Molecular Nutrition & Food Research - Wile...

Curcuminoids exert glucose-lowering effect in type 2 diabetes by decreasing serum free fatty acids: a double-blind, placebo-controlled trial - Na - 2012 - Molecular Nutrition & Food Research - Wile... | Longevity science | Scoop.it

This study found a possible glucose-lowering effect of curcuminoids in type 2 diabetes.

 

Curcuminoids are found in turmeric, the orange spice often used in Indian cuisine.

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Curry compound may curb diabetes risk: study

Curry compound may curb diabetes risk: study | Longevity science | Scoop.it

Researchers, whose results were published in the journal Diabetes Care, found that over nine months, a daily dose of curcumin seemed to prevent new cases of diabetes among people with so-called prediabetes - abnormally high blood sugar levels that may progress to full-blown type 2 diabetes.

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People who walk a lot have lower risk of diabetes

Among people with low physical activity and a high risk of diabetes, those who walk more throughout the day are less likely to actually get the blood sugar disorder, according to new research.

 

The study, published in the journal Diabetes Care, is part of a growing body of evidence that for people who get very little exercise, "even small amounts of activity will provide a really good return on their investment,"

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Potential Biomarker Emerging for Diabetic Neuropathy

Potential Biomarker Emerging for Diabetic Neuropathy | Longevity science | Scoop.it
An emerging biomarker may eventually lead to new approaches for treating diabetics at risk of developing nerve damage, UNSW researchers have found.

Via Brian Shields
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