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Experimental procedure shows promise for treatment of MS

Experimental procedure shows promise for treatment of MS | Longevity science | Scoop.it

An international team of scientists has recently reported success in the first phase of clinical trials in which MS victims’ immune systems were conditioned to become much more tolerant of myelin.\

 

In the study, white blood cells were obtained from nine MS-afflicted test subjects. These cells were specially processed, coupled with myelin antigens, and then injected intravenously back into their respective donors – up to 3 billion of these dead, treated cells were injected into each person.

 

When they entered the spleen, which filters dead cells from the bloodstream, both the white blood cells themselves and their myelin antigen payloads were identified by the body as being innocuous. This caused the immune system to become 50 to 75 percent less reactive to myelin, depending on the person and the number of cells injected.

 

 

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Researchers Identify Biomarker and Potential Therapy Target in MS ...

Researchers Identify Biomarker and Potential Therapy Target in MS ... | Longevity science | Scoop.it

Researchers discover proteins in the IL-6 signaling pathway may be leveraged as novel biomarkers of multiple sclerosis (MS) to gauge disease activity and as a target for new therapies.


Via Brian Shields
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Brain cells created from human skin cells offer potential MS treatment

Brain cells created from human skin cells offer potential MS treatment | Longevity science | Scoop.it
Using brain cells created from human skin cells, scientists may be on their way to developing a treatment for multiple sclerosis.

 

If the myelin of MS sufferers could be regrown, then it’s possible that the disease could be cured. Recently, a team of scientists successfully regenerated myelin in mice, using human skin cells that were reprogrammed into brain cells.

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Cure For Multiple Sclerosis? Treatment Wildly Popular Despite Scant Evidence It Works

Cure For Multiple Sclerosis? Treatment Wildly Popular Despite Scant Evidence It Works | Longevity science | Scoop.it

There are 2.1 million people worldwide suffering from multiple sclerosis. It is thought to be an autoimmune disorder in which the immune system attacks the body’s own nervous system. To date there is no known cure.

 

Most researchers and clinicians attribute the myelin damage to autoimmunity, the cause of which still remains uncertain. But Paolo Zamboni, a vascular surgeon at the University of Ferrara in Italy, disagrees.

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