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Longevity science
Live longer in good health and you will have a chance to extend your healthy life even further
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Elevated levels of human hormone motivates mice to exercise

Elevated levels of human hormone motivates mice to exercise | Longevity science | Scoop.it

A team of Swiss researchers has discovered that raising the levels of the hormone erythropoietin (Epo) in the brains of mice resulted in the rodents being more motivated to exercise.

 

The discovery provides the possibility of developing a pill that can motivate people to want to exercise.

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Artificial spinal disc designed to treat chronic lower back pain

Artificial spinal disc designed to treat chronic lower back pain | Longevity science | Scoop.it

 

More spare parts news!

 

The soft, collagen-rich shock absorbers in our backs, known as intervertebral discs, both add to our height (a full quarter of the spinal column's total length) and cushion our vertebrae from contacting one another. Unfortunately, aging, accidents and overuse can damage them and lead to the costly phenomenon of chronic back pain – roughly US$100 billion is spent annually on treatment in the U.S. alone.

 

Replacement of damaged discs, rather than spinal fusion, is an option that's growing in popularity, especially because it helps maintain mobility in the spine. Now, a team from Brigham Young University (BYU) has unveiled their new artificial disc, a compliant mechanism that they believe has the potential to restore quality of life to millions of those with injured spines.

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U.S. cancer survivors to rise by a third by 2022: report

U.S. cancer survivors to rise by a third by 2022: report | Longevity science | Scoop.it

Reuters) - The number of Americans living with cancer will increase by nearly a third to almost 18 million by 2022, according to a report released on Thursday by the American Cancer Society.

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Healthy Fish Recipes (Video)

Healthy Fish Recipes (Video) | Longevity science | Scoop.it

Most of us start with the most basic technique....grilling.  Think steak, hot dogs and burgers placed directly over the hot coals.  The fats drip and the flames flare.  Great taste. Delicious.  Memories of childhood summers. 

 

Well, the research finds that this type of cooking not only destroys the nutritional value of foods.  It also makes the foods harmful.

 

Overcooked and charred meats have been shown to be more highly linked to heart disease and cancer than meat more carefully prepared.  

High temperature, direct heat cooking causes fatty acids - the building blocks of oils and fats - to oxidize...

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Potential Biomarker Emerging for Diabetic Neuropathy

Potential Biomarker Emerging for Diabetic Neuropathy | Longevity science | Scoop.it
An emerging biomarker may eventually lead to new approaches for treating diabetics at risk of developing nerve damage, UNSW researchers have found.

Via Brian Shields
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Being heavy may help men with one type of cancer: study

Being heavy may help men with one type of cancer: study | Longevity science | Scoop.it

Reuters) - Extra weight may not be good for your health in general, but heavy men appear more likely to survive a particular form of immune system cancer, according to a U.S. study

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Awesome Video Explains Synthetic Biology | Singularity Hub

Awesome Video Explains Synthetic Biology | Singularity Hub | Longevity science | Scoop.it

"A succinct, yet powerful animation titled “Synthetic Biology Explained” shows the incredible potential of this emergent field and how engineering will transform the field of genetics to produce some truly amazing technology.

 

With the sequencing of the human genome and the increased understanding of genes that have followed..."

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A Countdown to a Digital Simulation of Every Last Neuron in the Human Brain: Scientific American

A Countdown to a Digital Simulation of Every Last Neuron in the Human Brain: Scientific American | Longevity science | Scoop.it

Building a vast digital simulation of the brain could transform neuroscience and medicine and reveal new ways of making more powerful computers.

 

Reductionist biology—examining individual brain parts, neural circuits and molecules—has brought us a long way, but it alone cannot explain the workings of the human brain, an information processor within our skull that is perhaps unparalleled anywhere in the universe. We must construct as well as reduce and build as well as dissect. To do that, we need a new paradigm

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Nokia Sensing X CHALLENGE seeks healthcare tech innovations

Nokia Sensing X CHALLENGE seeks healthcare tech innovations | Longevity science | Scoop.it

Nokia is sponsoring the Nokia Sensing X CHALLENGE. The US$2.25 million global competition is intended to “stimulate the development of sensors and sensing technology to drastically improve and expand the quality and access to healthcare across a wide variety of settings for consumers all around the globe.

 

Teams are required to submit a system, device, or component that can detect a physical value and record or interpret it. Those physical values could be applied to things such as biofluid and tissue samples, bodily structures, a patient’s external environment, body movements, mood/emotion, and body physics – that last category would include the measurement of vital signs such as heart rate, blood pressure, and respiratory rate.

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Anti-Inflammatory Drug with a New Benefit to Glucose

In a modern-day clinical trial of a medicine belonging to one of the world's oldest classes of drugs, researchers have found that a drug related to aspirin and salicylate, which was first used by ancient Egyptians and Greeks to ease pain caused by inflammation, also has glucose-lowering properties and may be a potential treatment for people with type 2 diabetes, according to results presented at the American Diabetes Association's 72nd Scientific Sessions(R).

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People on calorie restriction have better heart rate variability

People who restrict their caloric intake in an effort to live longer have hearts that function more like those in people who are 20 years younger.

Researchers at Washington University School of Medicine in St. Louis have found that a key measure of the heart's ability to adapt to physical activity, stress, sleep and other factors that influence the rate at which the heart pumps blood, doesn't decline nearly as rapidly in people who have significantly restricted their caloric intake for an average of seven years.

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Paralyzed Man Regains Use Of Hands After Having Nerves Rewired | Singularity Hub

Paralyzed Man Regains Use Of Hands After Having Nerves Rewired | Singularity Hub | Longevity science | Scoop.it

A quadriplegic man has regained partial control of his hands after doctors rewired the nerves in his arm.

The 71-year-old patient suffered a spinal cord injury after a car accident four years ago that left him partially paralyzed. Although he was still able to move his arms to a degree, the accident left him unable to pinch or grip with either hand, due to the specific location of his injury.

 

Surgeons...

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Tiny new sensor could simplify brain wave research

Tiny new sensor could simplify brain wave research | Longevity science | Scoop.it

"Two years ago, researchers at the National Institute of Standards and Technology (NIST) in the U.S. developed a tiny magnetic sensor that could detect the human heartbeat without touching the subject's skin. Now, the same team has improved the sensitivity of the device tenfold, making it capable of measuring human brain activity and becoming almost as sensitive - but much cheaper and easier to operate - than the best magnetometers available today."

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New Patch Makes Certain Skin Cancers Disappear | Singularity Hub

New Patch Makes Certain Skin Cancers Disappear | Singularity Hub | Longevity science | Scoop.it

Note that this is not fully successful yet, but an interesting prototype:

 

What if treating skin cancer was just a matter of wearing a patch for a few hours? At this year’s Society of Nuclear Medicine’s Annual Meeting one group of researchers presented such a patch.

 

The patch is infused with phosphorus-32, a radioactive isotope used to treat some types of cancer. In a study of 10 patients with basal cell carcinoma located on their faces, the patch was applied for three hours, then for another three hours four and seven days later. When biopsies were taken three months after treatment all ten patients, ranging from 32 to 74 years old, showed no traces of their tumors.

 

**When biopsies were performed again at six months, however, the basal cell carcinomas had returned in two of the patients.

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Vitamin D plus calcium tied to longer life: study

Older people who take vitamin D and calcium supplements may live a bit longer than their peers, according to an international review of several studies covering more than 70,000 people.

 

The percentage may sound small, but over a population, the numbers are significant.

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Virtual safety panel predicts drugs' side effects

Virtual safety panel predicts drugs' side effects | Longevity science | Scoop.it

A team of scientists from the UCSF School of Pharmacy, Novartis Institutes for Biomedical Research (NIBR) and SeaChange Pharmaceuticals has developed a set of computer models that can predict negative side effects associated with existing drugs. By speeding up the process and increasing accuracy, the software could potentially save billions in research and decrease the number of animals used in toxicity tests.

 

The model, based on UCSF’s “similarity ensemble approach” (SEA), uses the similarities between the shape of each drug and thousands of other compounds to predict possible side effects. The theory behind SEA technology is that proteins can be related by their pharmacology, and these network relationships can be explored to discover new targets for established drugs.

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Tracing the genetic pathway from the first Eukaryotes to Homo sapiens

Tracing the genetic pathway from the first Eukaryotes to Homo sapiens | Longevity science | Scoop.it

www.dhushara.com/book/unraveltree/unravel.htm

 

The Tree of Life, in biological terms, has come to be identified with the evolutionary tree of biological diversity. It is this tree which represents the climax fruitfulness of the biosphere and the genetic foundation of our existence, embracing not just higher Eukaryotes, plants, animals and fungi, but Protista, Eubacteria, and Archaea, the realm, including the extreme heat and salt-loving organisms, which appears to lie almost at the root of life itself.


Via Dr. Stefan Gruenwald
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Vein grown from stem cells saves 10-year-old girl

Doctors in Sweden have replaced a vital blocked blood vessel in a 10-year-old girl using the first vein grown in a lab from a patient's own stem cells.

 

The successful transplant operation, reported online in The Lancet medical journal on Thursday, marks a further advance in the search for ways to make new body parts.

 

It could open the door to stem cell-based grafts for heart bypass and dialysis patients who lack suitable blood vessels for replacement surgery, and the Swedish team said it is now working with an undisclosed company to commercialize the process.

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Flame retardants found in common grocery store foods

Flame retardants found in common grocery store foods | Longevity science | Scoop.it

HBCD - The newest player in toxic chemicals

In a recent study of best-selling grocery store products, researchers discovered that almost 50 percent of the sampled peanut butter and deli meats, as well as turkey, fish, beef and other fatty foods, contained hints of a flame retardant normally utilized in the foam insulation of building walls.

You're probably wondering how a chemical used in building insulation makes its way onto our grocery shelves.



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Do statins drain your energy?

There is a large population that take 'statin drugs' to lower cholesterol.

 

These drugs are very effective, but can result in muscle pain and fatigue. Why? The drugs deplete the body's natural reserves of CoEnzyme Q10, which is involved in energy production at the cellular level.

 

Fortunately, supplementing with the enzyme can help restore the blood levels and counterract the side effects. But few doctors mention this when they prescribe the drugs.

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Put this in your pipe-- no matter what, quitting helps

Put this in your pipe-- no matter what, quitting helps | Longevity science | Scoop.it
NEW YORK (Reuters Health) - Ex-smokers live longer than those who haven't kicked the habit, no matter what age group you look at, according to a new report.This fact calls for effective smoking cessation...
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Mind, body rest tied to concussion healing: study

Mind, body rest tied to concussion healing: study | Longevity science | Scoop.it
(Reuters) - Taking a week off from nearly all mental and physical activity - including television, talking on the phone and visiting with friends - was linked with improved mental performance and fewer...
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Movement-monitoring garment gives feedback for yoga, sport and dance

Movement-monitoring garment gives feedback for yoga, sport and dance | Longevity science | Scoop.it

Clothing that corrects your pose more gently than a yoga instructor.
This new design technology uses haptic sensors to assess and adjust your movements during exercise.

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Glaxo melanoma drugs beat chemo in pivotal trials

Late-stage trials of two experimental skin cancer drugs from GlaxoSmithKline, each designed to block different pathways used by tumor cells, have found the drugs helped patients with fewer side effects than current chemotherapy. Both drugs, trametinib and dabrafenib, were tested in patients with a mutation in a gene known as BRAF. About half of all melanomas, the deadliest form of skin cancer, have the genetic aberration.

 

Cancer occurs through genetic changes in cells allowing tumor growth factor receptors which activate various pathways, including a protein known as MEK. It is believed that BRAF-mutated melanomas should be particularly dependent on MEK, which is needed to amplify the cancer's genetic signal. Roche's Zelboraf, or vemurafenib, is the only BRAF inhibitor currently approved for treating melanoma. Latest results from a pivotal trial of the Roche drug, presented at a meeting in Chicago of the American Society of Clinical Oncology, found that it improved survival by nearly four months.


Via Dr. Stefan Gruenwald
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Good Fat vs. Low Fat | Kardea Nutrition

Wondering if a high-fat, heart healthy Mediterranean diet is better than the low fat heart healthy diets?

 

Kardea Nutrition has written a report that will help you find an answer that works for you.  Learn the 5 Rules for Eating Healthy Oils and the 6 Steps for Keeping Healthy Oils Healthy (pdf)

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