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Carbs Fog Aging Brains - Vital Choice

Carbs Fog Aging Brains - Vital Choice | Longevity science | Scoop.it

Mayo Clinic study in seniors finds that diets high in sugars and starches promote brain fog and dementia.

 

Correlations between carb intake and brain fog included:

*Those with the highest carbohydrate intake relative to total fat and protein intake were 3.6 times likelier to develop MCI.

 

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Chiba robotic wheelchair turns wheels into legs

Chiba robotic wheelchair turns wheels into legs | Longevity science | Scoop.it

Making a wheelchair that can deal with steps and other obstacles has puzzled engineers for decades, with everything from tank treads to spokes tried and found not quite practical.

 

Now a team of engineers from the Chiba Institute of Technology, led by associate professor Shuro Nakajima, have applied a bit of lateral thinking. They have developed a robotic wheelchair that isn't sure what it is. Normally, it operates on wheels like a conventional wheelchair, but when it meets an obstacle, the wheels turn into legs.

 

 

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New Biomarker May Allow Earlier Diagnosis of Mesothelioma

"Researchers have shown that the protein fibulin-3 may be able to distinguish patients with mesothelioma from people with similar conditions and from healthy individuals. Although preliminary, the results suggest that this protein may be a promising new biomarker for diagnosing the disease and possibly informing prognosis. The study was published October 11 in the New England Journal of Medicine.

 

Pleural mesothelioma, a disease of the tissue that lines the chest cavity and covers the lungs (the pleura), is an aggressive cancer often associated with asbestos exposure. Patients diagnosed with this disease have a median survival of 1 year.

 

Diagnosing mesothelioma early, when treatment may be most effective, is difficult because of its long latency period and the lack of reliable methods to detect the disease in its early stages. A protein called soluble mesothelin-related protein is the best-studied biomarker for mesothelioma, but the test for it has low sensitivity, meaning that it fails to detect mesothelioma in some people who have the disease.."


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Americans eat more than their body weight in GMOs every year, study shows

Americans eat more than their body weight in GMOs every year, study shows | Longevity science | Scoop.it
The consumer advocacy organization Environmental Working Group (EWG) has put out a new paper that estimates the average person's yearly consumption of genetically-modified organisms (GMOs).

 

And based on the figures, which EWG admits are very likely understated, the average person consumes more than their own body weight's worth of GMOs every single year.

 

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Green tea polyphenols shown to reduce blood sugar spikes

Green tea polyphenols shown to reduce blood sugar spikes | Longevity science | Scoop.it

Green tea extract may help control blood sugar levels, according to a new study.

 

In a mouse study, researchers administered EGCG, the active compound in green tea, to mice given substances such as fructose to spike their blood sugar levels. The extract reduced glucose levels in the mice induced to postprandial spikes with corn starch or sucrose.

 

This study suggests that green tea extract may help reduce the risk of metabolic syndrome by helping to control blood sugar levels.

 

The study concluded:

"Our results suggest that EGCG acutely reduces postprandial blood glucose levels in mice when coadministered with CCS and this may be due in part to inhibition of α-amylase. The relatively low effective dose of EGCG makes a compelling case for studies in human subjects."

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Study shows Vitamin C intake protects (animal subjects) from bone loss: PLOS ONE

Epidemiologic studies correlate low vitamin C intake with bone loss. The genetic deletion of enzymes involved in de novo vitamin C synthesis in mice, likewise, causes severe osteoporosis. However, very few studies have evaluated a protective role of this dietary supplement on the skeleton.

 

Study authors show that the ingestion of vitamin C prevents the low-turnover bone loss following ovariectomy in mice. [They] show that this prevention in areal bone mineral density and micro-CT parameters results from the stimulation of bone formation, demonstrable in vivo by histomorphometry, bone marker measurements, and quantitative PCR.

 

Notably, the reductions in the bone formation rate, plasma osteocalcin levels, and ex vivo osteoblast gene expression 8 weeks post-ovariectomy are all returned to levels of sham-operated controls.

 

The study establishes vitamin C as a skeletal anabolic agent.

 

 

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Ray Kurzweil: Looking Forward to the Day That Humans Can Live Forever

Ray Kurzweil: Looking Forward to the Day That Humans Can Live Forever | Longevity science | Scoop.it
Speakers at the 7th Annual Singularity Summit predict a future in which everyone lives forever and the intelligence of man and machine fuse to usher in a new "human-machine civilization."...

 

Computing ability and technological innovation have been increasing exponentially over the past few decades, Ray stated, alongside similar increases in life expectancy and income.

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The big question: "What is the future of human physical enhancement?" (Wired UK)

The big question: "What is the future of human physical enhancement?" (Wired UK) | Longevity science | Scoop.it
Wired talks to the experts about what to expect from the future of the human ability...

 

Aubrey de Grey
Chief science officer, SENS Foundation
"Medicine is distinct from human enhancement, but they may intersect. Somatic gene therapy will treat many diseases including the defeat of aging, but also allow such enhancements as skin luminescence. Tissue engineering may also allow us to have gills. The sky is the limit."

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How to create beating heart muscle cells | KurzweilAI

How to create beating heart muscle cells | KurzweilAI | Longevity science | Scoop.it

UCLA stem-cell researchers have found for the first time a surprising and unexpected plasticity in the embryonic endothelium, the place where blood stem cells are made in early development.

 

They found that the lack of one transcription factor, a type of gene that controls cell fate (by regulating other genes), allows the precursors that normally generate blood stem and progenitor cells in blood-forming tissues to become something very unexpected — beating cardiomyocytes, or heart muscle cells.

 

 

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Friendly Bugs Cut Colds; Vitamin D Defeated - Vital Choice

Friendly Bugs Cut Colds; Vitamin D Defeated - Vital Choice | Longevity science | Scoop.it

Credible natural remedies for colds and similar viral respiratory infections emerged in recent years.

 

The most promising of these – based on limited clinical evidence – are zinc and Echinacea.

 

Probiotics have now joined the list. And it looks like Vitamin D has dropped off.

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Free Anti-Inflammation Webcast - Vital Choice

Free Anti-Inflammation Webcast - Vital Choice | Longevity science | Scoop.it

America's diets and lifestyles have created an escalating crisis of chronic inflammatory conditions … including diabetes, arthritis, asthma, allergies, obesity, heart disease, and many others.

 

Floyd “Ski” Chilton, Ph.D., is the author of Inflammation Nation and The Gene Smart Diet … and one of the world’s leading scientists in the field of nutrition and inflammation.

 

We wanted you to know that Dr. Chilton is hosting a free webcast, “3 Steps to Anti-Inflammatory Diet Success”, focused on curbing one key contributor to America’s major disease conditions.

 

Sign up at Vital Choice.

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Paula King, Ph.D.'s curator insight, August 24, 11:16 PM

This fellow and his book are new to me.  Inflammation Nation--let's see if it is evidence based.

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How cancer cells break free from tumors and spread | KurzweilAI

How cancer cells break free from tumors and spread | KurzweilAI | Longevity science | Scoop.it
A new study from MIT cancer researchers reveals some of the cellular adhesion molecules that are critical to this how cancer cells break free from tumors, spread, and reattach to a new site.

 

Although tumor metastasis (spreading) causes about 90 percent of cancer deaths, the exact mechanism that allows cancer cells to spread from one part of the body to another is not well understood.

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Scientists find blood signatures for aggressive prostate cancer - Indian Express

With the uncertaintly of the PSA test and the over treatment of thousands of men, we really need more breakthroughs in this area of research for Prostate Cancer Diagnosis.

 

I'm hopeful that this is the start of a breakthrough in non-invasive improved tests for men with Prostate Cancer.


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Cold viruses point the way to new cancer therapies | KurzweilAI

Cold viruses point the way to new cancer therapies | KurzweilAI | Longevity science | Scoop.it

The Salk findings may help scientists develop small molecules — the basis for the vast majority of current drugs — capable of destroying tumors by binding and disrupting large and complex cellular components that allow cancer cells to grow and spread.

 

Understanding how viruses overcome healthy cells may also help scientists engineer tumor-busting viruses, which offer a new and potentially self-perpetuating cancer therapy.

 

 

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Drug From Chinese ‘Thunder God Vine’ Kills Pancreas Tumors in Mice

Drug From Chinese ‘Thunder God Vine’ Kills Pancreas Tumors in Mice | Longevity science | Scoop.it

A drug made from a plant known as “thunder god vine,” or lei gong teng, that has been used in traditional Chinese medicine, wiped out pancreatic tumors in mice, researchers said, and may soon be tested in humans.

 

Mice treated with the compound showed no signs of tumors after 40 days or after discontinuing the treatment, according to researchers at the University of Minnesota’s Masonic Cancer Center. The research, funded by the university and the National Institutes of Health. was published today in the journal Science Translational Medicine.

 

“This drug is just unbelievably potent in killing tumor cells,” said Ashok Saluja, vice chairman of research at the center and the study’s leader, said in a telephone interview. “You could see that every day you looked at those mice, the tumor was decreasing and decreasing, and then just gone.”

 

The plant, also known as Tripterygium wilfordii, contains triptolide, which earlier studies have shown can cause cancer cells to die. In traditional Chinese medicine, the plant is used as a treatment for rheumatoid arthritis. While the researchers hope to start human trials in six months, Saluja said it’s still a long leap from mice to people.


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Study: Multivitamins may lower cancer risk in men

Study: Multivitamins may lower cancer risk in men | Longevity science | Scoop.it

America's favorite dietary supplements, multivitamins, modestly lowered the risk for cancer in healthy male doctors who took them for more than a decade, the first large study to test these pills has found.

 

The result is a surprise because many studies of individual vitamins have found they don't help prevent chronic diseases and some even seemed to raise the risk of cancer.

 

 

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Synthesizing collagen for drug design and disease treatments | KurzweilAI

Synthesizing collagen for drug design and disease treatments | KurzweilAI | Longevity science | Scoop.it

In a development that could lead to better drug design and new treatments for disease, Rice University researchers have made a major step toward synthesizing custom collagen, the fibrous protein that binds cells together into organs and tissues.

 

 

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Potential for blood test to detect lung cancer in early stages

Potential for blood test to detect lung cancer in early stages | Longevity science | Scoop.it

While the overall lung cancer five-year survival rate in the U.S. is 15 percent, the odds of survival increase significantly with early detection. However, the expense or invasiveness of current screening methods and the lack of symptoms at early stages of the disease means most people aren’t diagnosed until the cancer is well advanced.

 

Findings by researchers at the University of York could pave the way for a simple blood test that would detect the disease even in its early stages.

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Gold nanoparticle prostate cancer treatment targets without collateral damage (animal tests) | KurzweilAI

Gold nanoparticle prostate cancer treatment targets without collateral damage (animal tests) | KurzweilAI | Longevity science | Scoop.it

Animal studies have been conducted successfully using gold nanoparticles to target prostate cancer tumors. Next step-- human trials...

 

Current treatments for prostate cancer are not effective in patients who have aggressive prostate cancer tumors. Most of the time, prostate cancers are slow-growing; the disease remains localized and it is easily managed. However, aggressive forms of the disease spread to other parts of the body, and is the second-leading cause of cancer deaths in U.S. men.

 

The MU scientists believe their treatment will be able to shrink aggressive tumors or eliminate them completely. Axiak-Bechtel says this treatment can be safe and effective in dogs as well as humans because dogs are the only other mammal to naturally contract the aggressive form of prostate cancer.

 

 

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Scientists generate 281-gigapixel cell map using electron microscope

Scientists generate 281-gigapixel cell map using electron microscope | Longevity science | Scoop.it

Electron microscopes can produce incredibly detailed and even 3D views of sub-cellular structures, but often at the cost of losing the bigger picture. Researchers at Leiden University in the Netherlands, however, have leveraged a technique called virtual nanoscopy that enables researchers to observe the whole of a cell and its intricate details in a single image.

 

With the method, the team stitches together nanometer resolution photographs of what's gone under the scope to create a map with adjustable zoom a la Google Maps. Their study created a 281-gigapixel image (packed with 16 million pixels per inch) of a 1.5-millimeter-long zebrafish embryo.


Via Anne Osterrieder, Dr. Stefan Gruenwald
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Apple a day? Really can help with cancer-protection and weight loss

Apple a day? Really can help with cancer-protection and weight loss | Longevity science | Scoop.it
Apple's Amazing Polyphenols

In the past five years, no area of apple research has been more dynamic than the area of apple polyphenols. The balance of these phytonutrients in apples is far more unique than many researchers previously suspected.

 

In terms of flavonols, quercetin is the primary phytonutrient found in apples, and it's far more concentrated in the skin than in the pulp. Kaempferol and myricetin are also important apple flavonols.

 

Chlorogenic acid is apple's primary phenolic acid, and it's found throughout the pulp and also in the skin. Chlorogenic acid is a metabolism boosting compound also found in the popular new green coffee bean extracts. It help supress appetite and stimulate weight loss.

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Nutrition Journal | Abstract | Diverse effects of a low dose supplement of lipidated curcumin in healthy middle aged people

Curcumin extracts of turmeric are proposed to produce health benefits. To date, human intervention studies have focused mainly on people with existing health problems given high doses of poorly absorbed curcumin.

 

In this small study, absorbable low doses of curcumin were seen to produce positive effects in healthy middle aged people. The results of the small study indicate that curcumin helps to protect health heart, brain, and immune system function.


>Disilvestro RA, Joseph E, Zhao S, Joshua B. Diverse effects of a low dose supplement of lipidated curcumin in healthy middle aged people. Nutr J. 2012 Sep 26;11(1):79. [Epub ahead of print]

 

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3D model for lung cancer mimics the real thing | KurzweilAI

3D model for lung cancer mimics the real thing | KurzweilAI | Longevity science | Scoop.it

Using a new technique that allows scientists to grow lung cancer cells in three dimensions, researchers at The Methodist Hospital and the University of Texas MD Anderson Cancer Center have created a model that uses biological matter to form miniature lungs that mimic the structure and function of real lung cancer, after which human lung cancer cells are added.

 

 

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Magnesium may reduce colon cancer risk: Meta-analysis

Magnesium may reduce colon cancer risk: Meta-analysis | Longevity science | Scoop.it
Increased intakes of magnesium may reduce the risk of developing colon cancer, says a new meta-analysis of data from 338,979 people.

 

The decrease risk is small, just 7% for each 50mg increase in magnesium intake. A large percentage of people do not get the recommended intake of this mineral.

 

Based on this evidence, it appears that even attaining the RDA would offer many people additional health protection. 

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Vitamin K may slash diabetes risk: Study

Increased intakes of vitamin K1 may lower the risk of developing type-2 diabetes in elderly people with a high risk of cardiovascular disease, says a new study.

 

There is an irony in these results. Most people over the age of 60 with a risk of cardiovascular disease (and virtually all people over 75) are prescribed warfarin, a blood thinning medication.

 

Vitamin K contributes to clotting. In patients on warfarin, Vitamin K intake is discouraged to make it easier to regulate medication levels and maintain a proper blood flow.

 

Vitamin K is found in many vegetables with additional health properties such as broccoli and leafy greens. If an increase in this vitamin could help lower the risk of diabetes, some patients may have to make a decision whether they can properly regulate their levels on warfarin.

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