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Britons invited to post their genomes online for science

The hunt is on for 100,000 British volunteers to post their genetic information online in the name of science as a North American open-access DNA project arrives in Europe.

 

The launch of the Personal Genome Project UK on Thursday offers the public a chance to learn more about their own genetic profiles and contribute to advances in medical science - but it also poses ethical challenges.

 

Unlike other genome-sequencing initiatives, where data is placed behind a firewall, information contributed to the new project will be available to all.

 

 

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Leading Research Hospital Spins Out a For-Profit Company to Bring Gene Therapy To Market

Leading Research Hospital Spins Out a For-Profit Company to Bring Gene Therapy To Market | Longevity science | Scoop.it

Gene therapy, in which DNA is administered to patients in hopes of triggering a fix for genetic diseases, was one of many potential medical applications for the big, expensive sequencing projects of the 1990s that were breathlessly hyped by doctors and reporters.

 

And yet no gene therapy treatment has yet been approved for general use in the United States and just one has been approved in Europe.

 

But the winds may be shifting for commercial gene therapy. The Children’s Hospital of Philadelphia has placed a $50-million bet on a spinoff company called Spark Therapeutics that will take over the testing, and hopefully marketing, of several treatments developed there.

 

 

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To prevent allergic reactions, you might try washing bed pillows and microwaving fruit

To prevent allergic reactions, you might try washing bed pillows and microwaving fruit | Longevity science | Scoop.it
There is a lot of conventional wisdom about allergies — and how to handle them — and not all of it is right.
Ray and Terry's 's insight:

Try these tips to minimize allergen exposure.

 

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How nanotechnology can advance regenerative medicine | KurzweilAI

How nanotechnology can advance regenerative medicine | KurzweilAI | Longevity science | Scoop.it

Nanotechnology may provide new strategies for regenerative medicine, including better tools to improve or restore damaged tissues, according to a review paper that summarizes the current state of knowledge on nanotechnology with application to stem cell biology.

 

Researchers have found that the adhesion, growth, and differentiation of stem cells are likely controlled by their surrounding microenvironment, which contains both chemical and physical cues. These cues include the “nanotopography” of the complex extracellular matrix or architecture that forms a network for human tissues.

 

 

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Pacemaker Okayed in Europe Is One-Tenth the Size of Those Used Now

Pacemaker Okayed in Europe Is One-Tenth the Size of Those Used Now | Longevity science | Scoop.it

In the coming year, it will likely become significantly easier to receive and live with a pacemaker.

 

Developed by Silicon Valley startup Nanostim, a device about the size of a AAA battery, or one-tenth the size of a conventional pacemaker, was recently approved for use in Europe. It is installed through a catheter in the femoral vein in a minimally invasive procedure. Then, for about 10 years it sits inside the ventricle of the heart and delivers its regulatory electrical pulses wirelessly.

 

 

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A multifunctional nano carrier to detect, diagnose, and deliver drugs to cancer cells | KurzweilAI

A multifunctional nano carrier to detect, diagnose, and deliver drugs to cancer cells | KurzweilAI | Longevity science | Scoop.it

A unique nanostructure developed by a team of international researchers promises improved all-in-one detection, diagnoses, and drug-delivery treatment of cancer cells.

 

It can carry a variety of cancer-fighting materials on its double-sided (Janus) surface and within its porous interior and can:

 

-Transport cancer-specific detection nanoparticles....

 

 

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Elderly exercisers have fewer broken bones after falls

Older adults who exercise are less likely to fall, but if they do, they're also less likely to get hurt, a new analysis suggests.

 

Researchers found that older adults taking part in fall prevention exercise programs were about 37 percent less likely to be injured during a tumble, compared to non-exercising participants.

 

 

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Diagnostic devices the size of a credit card | KurzweilAI

Diagnostic devices the size of a credit card | KurzweilAI | Longevity science | Scoop.it

A silicon nanomembrane developed at the University of Rochester could drastically shrink the  power source needed with electroosmotic pumps (EOPs) to move solutions through micro-channels — paving the way for ultra-thin ”lab-on-a-chip” diagnostic devices the size of a credit card.

 

 

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Curcumin Eased Alzheimer’s in Animals

Curcumin Eased Alzheimer’s in Animals | Longevity science | Scoop.it

Alzheimer’s disease is characterized by formation of a “plaque” made of inflammation-inducing proteins called beta-amyloid, which also form wiry tangles.

 It remains uncertain whether amyloid plaque and tangles cause or result from the still-mysterious process that leads to Alzheimer’s disease (AD). Drugs and nutrients that inhibit inflammation, oxidation, and formation of amyloid plaque and tangles also reduce AD symptoms.
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Omega-3s May Deter Silent Brain Damage

Omega-3s May Deter Silent Brain Damage | Longevity science | Scoop.it
Five years ago, researchers gave people diet questionnaires and MRI brain scans, and compared the results of both. And that U.S.-Finnish  team found fewer “silent” brain abnormalities in the brains of people who reported eating fish frequently (Virtanen JK et al. 2008). 
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Hydrogel implant enables light-based communication with cells inside the body | KurzweilAI

Hydrogel implant enables light-based communication with cells inside the body | KurzweilAI | Longevity science | Scoop.it

Researchers at the Wellman Center for Photomedicine at Massachusetts General Hospital have developed a way to deliver a light signal to specific tissues deep within the body for sensing or treatment.

 

The use of light to communicate with cells has previously been restricted by its limited ability to pass through tissues, especially the skin.

 

Called a light-guiding hydrogel, the implant is constructed from a polymer-based scaffolding capable of supporting living cells and contains cells genetically engineered either to carry out a specific activity in response to light or to emit light in response to a particular metabolic signal.

 

 

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Coffee consumption may reduce risk of liver cancer: Meta-analysis

Coffee consumption may reduce risk of liver cancer: Meta-analysis | Longevity science | Scoop.it
Consumption of coffee may reduce the risk of hepatocellular carcinoma (HCC), the most common type of liver cancer, by about 40%, according to a new meta-analysis.
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Converting fat cells from liposection to liver cells in nine days — a regenerative medicine breakthrough | KurzweilAI

Converting fat cells from liposection to liver cells in nine days — a regenerative medicine breakthrough | KurzweilAI | Longevity science | Scoop.it

A fast, efficient way to turn cells extracted from routine liposuction into liver cells — a feat with huge potential for regenerative medicine — has been developed by Stanford University School of Medicine scientists

 

The scientists performed their experiments in mice, but the adipose (fat) stem cells they used came from human liposuction and actually became human, liver-like cells that flourished inside the mice’s bodies.

 

This method is distinct from those producing liver cells from embryonic stem cells or induced pluripotent stem cells (iPS). Although embryonic and iPS stem cells are pluripotent — they can, in principle, differentiate into every cell type — they carry a palpable risk of forming tumors.

 

 

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U.S. FDA moves to ban trans fats, citing health risks

U.S. FDA moves to ban trans fats, citing health risks | Longevity science | Scoop.it

The U.S. Food and Drug Administration on Thursday proposed banning artificial trans fat in processed food, a move that was welcomed by public health advocates but which rattled vegetable oil markets and pushed prices down sharply.

 

The FDA said reducing partially hydrogenated oils (PHOs) from the American diet could prevent 7,000 deaths from heart disease each year.

 

If its proposal becomes final, the oils, the primary dietary source of artificial trans fat, would be considered food additives and could not be used in food unless authorized.

 

 

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Steve Kingsley's curator insight, November 7, 2013 7:51 PM

About time - actually way past time!

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Q&A: I have prediabetes. What should I eat?

Q&A: I have prediabetes. What should I eat? | Longevity science | Scoop.it

Q: What should I eat if I’ve been told by my health-care provider that I have prediabetes? I’m confused by the conflicting messages I hear and read.

 

A: November is an apt month to answer this increasingly common question. It’s American Diabetes Month.

 

 

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Testosterone tied to heart risks among older men

Older men who take testosterone are more likely to have a heart attack or stroke or die over the next few years, new research indicates.

 

The study included men who were in their early 60s, on average. Most of them already had blocked heart arteries, high blood pressure, diabetes and other health problems.

 

So it's unclear what the findings mean for younger, healthier men who take testosterone, researchers said.

 

 

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Discovery shines a light on potential cure for Alzheimer's and Parkinson's

Discovery shines a light on potential cure for Alzheimer's and Parkinson's | Longevity science | Scoop.it

It is generally believed that aggregations of proteins are responsible for brain disorders such as Alzheimer's, Parkinson's and Creutzfeldt-Jakob disease. However, the difficulty has been in detecting the aggregates responsible and removing them from the brain. Researchers at Chalmers University of Technology in Sweden and Polish Wroclaw University of Technology have found a potential solution using lasers.

 

Alzheimer's, Parkinson's and Creutzfeldt-Jakob disease are thought to be caused by aggregates of amyloid beta protein that start to inhibit proper cellular processes in the brain. Although it is technically possible to cure the diseases by detecting and removing the amyloid protein aggregates using chemicals, these chemicals are highly toxic and harmful to the patient.

 

 

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‘Intensive' exercise may benefit heart failure patients

Some doctors caution people with heart failure against pushing themselves too hard physically. But a new analysis of past studies suggests heart patients may actually benefit more from relatively intensive exercise.

 

Researchers found people with heart failure had a 23-percent improvement in heart function after taking part in relatively high-intensity exercise programs. That compared to a 7-percent improvement among those in low-intensity programs.

 

 

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Compound blocks neurodegeneration in mice | KurzweilAI

An orally administered compound that prevents neurodegeneration in mice has been developed by researchers at the Medical Research Council (MRC) Toxicology Unit at the University of Leicester.

 

The team had found previously (Nature) that the build up of misfolded proteins in the brains of mice with prion disease over-activates a natural defense mechanism in cells, which switches off the production of new proteins.

 

This mechanism would normally switch back on again, but in these mice, the continued buildup of misshapen protein keeps the switch turned off. This is the trigger point leading to brain cell death, since the key proteins essential for nerve cell survival stop being made.

 

 

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Medtronic heart valve found to reduce death, stroke rate

Medtronic Inc's CoreValve heart valve implant significantly lowered death and stroke rates in frail, elderly patients with severe aortic stenosis who were considered too ill for surgery, according to data from a late-stage clinical trial.

 

 

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Can Multi-Vitamins Aid Breast Cancer Survival?

Can Multi-Vitamins Aid Breast Cancer Survival? | Longevity science | Scoop.it
Three years ago, a novel study looked for links between women’s use of vitamin and calcium supplements, and their risk for breast cancer risk. The researchers reached an encouraging conclusion: “Vitamins and calcium intake are protective for breast cancer.” (Vergne y et al. 2010). Women who took vitamin supplements were 30 percent less likely to have breast cancer, and women who took calcium supplements were 40 percent less likely to have breast cancer
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Tiny capsule adds a sense of touch to laparoscopic surgery

Tiny capsule adds a sense of touch to laparoscopic surgery | Longevity science | Scoop.it

Researchers at Nashville's Vanderbilt University have developed a wireless capsule that can restore a sense of touch for surgeons. Keyhole surgeries or other minimally invasive procedures could benefit greatly from this new technology, as the capsule provides haptic feedback to help doctors maneuver and make important conclusions during surgery.

 

 

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DIY Biology or Our Biohacker Future

DIY Biology or Our Biohacker Future | Longevity science | Scoop.it

Biohackers constructed their temple for amatuer bio-creativity in 2009, with the establishment of Brooklyn-based Genspace, the world’s first government-compliant DIY biotech lab.

 

 

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OpEdNews Article: Article: Nanomedicine: The Future of Medicine

OpEdNews Article: Article: Nanomedicine: The Future of Medicine | Longevity science | Scoop.it
Nanomedicine, refers to highly specific medical intervention at the molecular level for curing disease or repairing damaged tissues. Though in its infancy, could we be looking at the future of medicine?
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Fitness and health norms: Don’t get too worked up about them

Fitness and health norms: Don’t get too worked up about them | Longevity science | Scoop.it
Experts say to keep an eye on some norms, but don't get caught up in what everyone else can do.

 

If there’s one measure you should pay attention to as you get older, it’s your cardiovascular fitness. Here’s why: Numerous studies have proved that it is the single best predictor of mortality from any cause, not just diseases of the heart, lungs and circulatory system.

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