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Testosterone tied to heart risks among older men

Older men who take testosterone are more likely to have a heart attack or stroke or die over the next few years, new research indicates.

 

The study included men who were in their early 60s, on average. Most of them already had blocked heart arteries, high blood pressure, diabetes and other health problems.

 

So it's unclear what the findings mean for younger, healthier men who take testosterone, researchers said.

 

 

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Discovery shines a light on potential cure for Alzheimer's and Parkinson's

Discovery shines a light on potential cure for Alzheimer's and Parkinson's | Longevity science | Scoop.it

It is generally believed that aggregations of proteins are responsible for brain disorders such as Alzheimer's, Parkinson's and Creutzfeldt-Jakob disease. However, the difficulty has been in detecting the aggregates responsible and removing them from the brain. Researchers at Chalmers University of Technology in Sweden and Polish Wroclaw University of Technology have found a potential solution using lasers.

 

Alzheimer's, Parkinson's and Creutzfeldt-Jakob disease are thought to be caused by aggregates of amyloid beta protein that start to inhibit proper cellular processes in the brain. Although it is technically possible to cure the diseases by detecting and removing the amyloid protein aggregates using chemicals, these chemicals are highly toxic and harmful to the patient.

 

 

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‘Intensive' exercise may benefit heart failure patients

Some doctors caution people with heart failure against pushing themselves too hard physically. But a new analysis of past studies suggests heart patients may actually benefit more from relatively intensive exercise.

 

Researchers found people with heart failure had a 23-percent improvement in heart function after taking part in relatively high-intensity exercise programs. That compared to a 7-percent improvement among those in low-intensity programs.

 

 

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Compound blocks neurodegeneration in mice | KurzweilAI

An orally administered compound that prevents neurodegeneration in mice has been developed by researchers at the Medical Research Council (MRC) Toxicology Unit at the University of Leicester.

 

The team had found previously (Nature) that the build up of misfolded proteins in the brains of mice with prion disease over-activates a natural defense mechanism in cells, which switches off the production of new proteins.

 

This mechanism would normally switch back on again, but in these mice, the continued buildup of misshapen protein keeps the switch turned off. This is the trigger point leading to brain cell death, since the key proteins essential for nerve cell survival stop being made.

 

 

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Medtronic heart valve found to reduce death, stroke rate

Medtronic Inc's CoreValve heart valve implant significantly lowered death and stroke rates in frail, elderly patients with severe aortic stenosis who were considered too ill for surgery, according to data from a late-stage clinical trial.

 

 

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Can Multi-Vitamins Aid Breast Cancer Survival?

Can Multi-Vitamins Aid Breast Cancer Survival? | Longevity science | Scoop.it
Three years ago, a novel study looked for links between women’s use of vitamin and calcium supplements, and their risk for breast cancer risk. The researchers reached an encouraging conclusion: “Vitamins and calcium intake are protective for breast cancer.” (Vergne y et al. 2010). Women who took vitamin supplements were 30 percent less likely to have breast cancer, and women who took calcium supplements were 40 percent less likely to have breast cancer
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Tiny capsule adds a sense of touch to laparoscopic surgery

Tiny capsule adds a sense of touch to laparoscopic surgery | Longevity science | Scoop.it

Researchers at Nashville's Vanderbilt University have developed a wireless capsule that can restore a sense of touch for surgeons. Keyhole surgeries or other minimally invasive procedures could benefit greatly from this new technology, as the capsule provides haptic feedback to help doctors maneuver and make important conclusions during surgery.

 

 

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DIY Biology or Our Biohacker Future

DIY Biology or Our Biohacker Future | Longevity science | Scoop.it

Biohackers constructed their temple for amatuer bio-creativity in 2009, with the establishment of Brooklyn-based Genspace, the world’s first government-compliant DIY biotech lab.

 

 

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OpEdNews Article: Article: Nanomedicine: The Future of Medicine

OpEdNews Article: Article: Nanomedicine: The Future of Medicine | Longevity science | Scoop.it
Nanomedicine, refers to highly specific medical intervention at the molecular level for curing disease or repairing damaged tissues. Though in its infancy, could we be looking at the future of medicine?
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Fitness and health norms: Don’t get too worked up about them

Fitness and health norms: Don’t get too worked up about them | Longevity science | Scoop.it
Experts say to keep an eye on some norms, but don't get caught up in what everyone else can do.

 

If there’s one measure you should pay attention to as you get older, it’s your cardiovascular fitness. Here’s why: Numerous studies have proved that it is the single best predictor of mortality from any cause, not just diseases of the heart, lungs and circulatory system.

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Potential baldness treatment grows new hair using patient's own cells

Potential baldness treatment grows new hair using patient's own cells | Longevity science | Scoop.it

Current hair transplantation techniques essentially rob Peter to pay Paul, redistributing hair, usually from the back of the head, to the balding area. However, according to Angela M. Christiano, PhD, from Columbia University Medical Center (CUMC), about 90 percent of women with hair loss are not strong candidates for hair transplantation surgery because of insufficient donor hair.

 

A new technique developed by Dr Christiano and colleagues that generates new human hair growth from a patient's own cells could make transplantation feasible for such women, as well as men in the early stages of baldness.

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IBM's Watson adapted to teach medical students and aid diagnosis

IBM's Watson adapted to teach medical students and aid diagnosis | Longevity science | Scoop.it

When IBM’s Watson supercomputer took on two human champions of the television quiz show Jeopardy and won, it was hailed as a breakthrough in machine intelligence. Now in an effort to expand the practical applications for the "world’s smartest computer," IBM Research and has taken the wraps off two new projects aimed at the medical community.

 

 

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Self-contained mini pacemaker is implanted right into the heart

Self-contained mini pacemaker is implanted right into the heart | Longevity science | Scoop.it

Ordinarily, a pacemaker is surgically implanted below the collarbone, where it sits in a sizable pocket under the skin. Electrical leads run from it to the heart, allowing it to monitor the rhythm of the heartbeat, and deliver electrical pulses to adjust that rhythm as needed.

 

Now, however, Minnesota-based St. Jude Medical has announced upcoming availability of "the world’s first and only commercially available leadless pacemaker." Known as the Nanostim, it's reportedly less than 10 percent the size of a regular pacemaker, and is inserted directly into the heart via a minimally-invasive procedure.

 

 

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How nanotechnology can advance regenerative medicine | KurzweilAI

How nanotechnology can advance regenerative medicine | KurzweilAI | Longevity science | Scoop.it

Nanotechnology may provide new strategies for regenerative medicine, including better tools to improve or restore damaged tissues, according to a review paper that summarizes the current state of knowledge on nanotechnology with application to stem cell biology.

 

Researchers have found that the adhesion, growth, and differentiation of stem cells are likely controlled by their surrounding microenvironment, which contains both chemical and physical cues. These cues include the “nanotopography” of the complex extracellular matrix or architecture that forms a network for human tissues.

 

 

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Pacemaker Okayed in Europe Is One-Tenth the Size of Those Used Now

Pacemaker Okayed in Europe Is One-Tenth the Size of Those Used Now | Longevity science | Scoop.it

In the coming year, it will likely become significantly easier to receive and live with a pacemaker.

 

Developed by Silicon Valley startup Nanostim, a device about the size of a AAA battery, or one-tenth the size of a conventional pacemaker, was recently approved for use in Europe. It is installed through a catheter in the femoral vein in a minimally invasive procedure. Then, for about 10 years it sits inside the ventricle of the heart and delivers its regulatory electrical pulses wirelessly.

 

 

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A multifunctional nano carrier to detect, diagnose, and deliver drugs to cancer cells | KurzweilAI

A multifunctional nano carrier to detect, diagnose, and deliver drugs to cancer cells | KurzweilAI | Longevity science | Scoop.it

A unique nanostructure developed by a team of international researchers promises improved all-in-one detection, diagnoses, and drug-delivery treatment of cancer cells.

 

It can carry a variety of cancer-fighting materials on its double-sided (Janus) surface and within its porous interior and can:

 

-Transport cancer-specific detection nanoparticles....

 

 

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Elderly exercisers have fewer broken bones after falls

Older adults who exercise are less likely to fall, but if they do, they're also less likely to get hurt, a new analysis suggests.

 

Researchers found that older adults taking part in fall prevention exercise programs were about 37 percent less likely to be injured during a tumble, compared to non-exercising participants.

 

 

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Diagnostic devices the size of a credit card | KurzweilAI

Diagnostic devices the size of a credit card | KurzweilAI | Longevity science | Scoop.it

A silicon nanomembrane developed at the University of Rochester could drastically shrink the  power source needed with electroosmotic pumps (EOPs) to move solutions through micro-channels — paving the way for ultra-thin ”lab-on-a-chip” diagnostic devices the size of a credit card.

 

 

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Curcumin Eased Alzheimer’s in Animals

Curcumin Eased Alzheimer’s in Animals | Longevity science | Scoop.it

Alzheimer’s disease is characterized by formation of a “plaque” made of inflammation-inducing proteins called beta-amyloid, which also form wiry tangles.

 It remains uncertain whether amyloid plaque and tangles cause or result from the still-mysterious process that leads to Alzheimer’s disease (AD). Drugs and nutrients that inhibit inflammation, oxidation, and formation of amyloid plaque and tangles also reduce AD symptoms.
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Omega-3s May Deter Silent Brain Damage

Omega-3s May Deter Silent Brain Damage | Longevity science | Scoop.it
Five years ago, researchers gave people diet questionnaires and MRI brain scans, and compared the results of both. And that U.S.-Finnish  team found fewer “silent” brain abnormalities in the brains of people who reported eating fish frequently (Virtanen JK et al. 2008). 
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Hydrogel implant enables light-based communication with cells inside the body | KurzweilAI

Hydrogel implant enables light-based communication with cells inside the body | KurzweilAI | Longevity science | Scoop.it

Researchers at the Wellman Center for Photomedicine at Massachusetts General Hospital have developed a way to deliver a light signal to specific tissues deep within the body for sensing or treatment.

 

The use of light to communicate with cells has previously been restricted by its limited ability to pass through tissues, especially the skin.

 

Called a light-guiding hydrogel, the implant is constructed from a polymer-based scaffolding capable of supporting living cells and contains cells genetically engineered either to carry out a specific activity in response to light or to emit light in response to a particular metabolic signal.

 

 

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Coffee consumption may reduce risk of liver cancer: Meta-analysis

Coffee consumption may reduce risk of liver cancer: Meta-analysis | Longevity science | Scoop.it
Consumption of coffee may reduce the risk of hepatocellular carcinoma (HCC), the most common type of liver cancer, by about 40%, according to a new meta-analysis.
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Converting fat cells from liposection to liver cells in nine days — a regenerative medicine breakthrough | KurzweilAI

Converting fat cells from liposection to liver cells in nine days — a regenerative medicine breakthrough | KurzweilAI | Longevity science | Scoop.it

A fast, efficient way to turn cells extracted from routine liposuction into liver cells — a feat with huge potential for regenerative medicine — has been developed by Stanford University School of Medicine scientists

 

The scientists performed their experiments in mice, but the adipose (fat) stem cells they used came from human liposuction and actually became human, liver-like cells that flourished inside the mice’s bodies.

 

This method is distinct from those producing liver cells from embryonic stem cells or induced pluripotent stem cells (iPS). Although embryonic and iPS stem cells are pluripotent — they can, in principle, differentiate into every cell type — they carry a palpable risk of forming tumors.

 

 

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Poor sleep tied to Alzheimer's-like brain changes

Older adults who don't sleep well have more of the brain plaques that are hallmarks of Alzheimer's disease, a new study suggests.

 

The finding doesn't prove that not getting enough shut-eye causes the build-up of beta-amyloid plaques and leads to dementia rather than the other way around.

 

 

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Steve Kingsley's curator insight, October 22, 2013 9:34 PM

Poor sleep can lead to cognitive decline - one reason is that it doesn't allow all of the metabolic byproducts, produced during the day, "wash out" of the brain.

Scott Baker's curator insight, October 23, 2013 12:15 PM

I can't sleep more than 5 hours/night - nothing works, not even sleeping pills.  I am 55.  Does this mean I am headed for Alzheimer's?  :(

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Air pollution a leading cause of cancer - U.N. agency

Air pollution a leading cause of cancer - U.N. agency | Longevity science | Scoop.it

The air we breathe is laced with cancer-causing substances and is being officially classified as carcinogenic to humans, the World Health Organization's cancer agency said on Thursday.

 

The International Agency for Research on Cancer (IARC) cited data indicating that in 2010, 223,000 deaths from lung cancer worldwide resulted from air pollution, and said there was also convincing evidence it increases the risk of bladder cancer.

 

 

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Steve Kingsley's curator insight, October 21, 2013 8:50 PM

I grew up in Hungary in the 50s and 60s, when the air was as dirty as it is now in the large cities and industrial centers in China - yet neither I nor anyone else in my family has had cancer....