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Extracting human DNA with full genetic data in minutes | KurzweilAI

Extracting human DNA with full genetic data in minutes | KurzweilAI | Longevity science | Scoop.it

University of Washington engineers and NanoFacture, a Bellevue, Wash., company, have created a device that can extract human DNA from fluid samples in a simpler, more efficient and environmentally friendly way than conventional methods.

The device will give hospitals and research labs a much easier way to separate DNA from human fluid samples, which will help with genome sequencing, disease diagnosis and forensic investigations.

 

 

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Longevity science
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Red-light-sensitive protein enables noninvasive neuron studies | KurzweilAI

Red-light-sensitive protein enables noninvasive neuron studies | KurzweilAI | Longevity science | Scoop.it
(Credit: Jose-Luis Olivares/MIT) MIT engineers have developed the first light-sensitive protein molecule that enables neurons to be silenced noninvasively.
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Substantial Health And Economic Returns From Delayed Aging May Warrant A New Focus For Medical Research

Substantial Health And Economic Returns From Delayed Aging May Warrant A New Focus For Medical Research | Longevity science | Scoop.it

Recent scientific advances suggest that slowing the aging process (senescence) is now a realistic goal. Yet most medical research remains focused on combating individual diseases. Using the Future Elderly Model—a microsimulation of the future health and spending of older Americans—we compared optimistic “disease specific” scenarios with a hypothetical “delayed aging” scenario in terms of the scenarios’ impact on longevity, disability, and major entitlement program costs. Delayed aging could increase life expectancy by an additional 2.2 years, most of which would be spent in good health.


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Researchers regrow human corneas in mice | KurzweilAI

Researchers regrow human corneas in mice | KurzweilAI | Longevity science | Scoop.it
A restored functional cornea following transplantation of human ABCB5-positive limbal stem cells to limbal stem cell-deficient mice (credit: Kira Lathrop,
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MIT researchers augment humans with extra robotic arms

MIT researchers augment humans with extra robotic arms | Longevity science | Scoop.it
A team at MIT is developing extra robot limbs that can help out humans with everyday tasks where an extra hand, arm, or leg might be useful. The robot can a...
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Engineered red blood cells could carry therapeutic or diagnostic payloads | KurzweilAI

Engineered red blood cells could carry therapeutic or diagnostic payloads | KurzweilAI | Longevity science | Scoop.it
Human red blood cells supported on a glass slide (credit: Whitehead Institute) Whitehead Institute scientists and associates have modified red blood cells
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Changes in ambient temperature found to influence brown fat levels

Changes in ambient temperature found to influence brown fat levels | Longevity science | Scoop.it

The discovery that lowering your body temperature leads to an increase in a certain type of "good" fat might have some ditching the diet books and shedding a layer of clothing instead.


A study conducted at the National Institute of Health (NIH) in Washington has demonstrated that changes in ambient temperature affects brown fat levels in humans, pointing to potential treatment options for the weight-wary and sufferers of diabetes.



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Delivering Capsules of Stem Cells Helps Repair Injured Bones

Delivering Capsules of Stem Cells Helps Repair Injured Bones | Longevity science | Scoop.it
For the recorder of potentially breakthrough medical technology, sometimes it seems that the list is just so many applications of three new
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What’s expected at Google I/O conference | KurzweilAI

Ray Kurzweil, director of engineering at Google, has been slated to give a lecture entitle ”Biologically Inspired Models of Intelligence.”


Kurzweil was said to be preparing to present his short and long term plans for bolstering user interaction with artificial intelligence, helping to improve areas including searches and machine responses.



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Discovery of abnormal GABA levels may lead to improvements in diagnosing, treating Alzheimer’s disease | KurzweilAI

Discovery of abnormal GABA levels may lead to improvements in diagnosing, treating Alzheimer’s disease | KurzweilAI | Longevity science | Scoop.it
A new drug target to fight Alzheimer's disease has been discovered by a research team led by Gong Chen at Penn State that also has potential for development as
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Artificial human blood substitute could help meet donor blood shortfall

Artificial human blood substitute could help meet donor blood shortfall | Longevity science | Scoop.it
Through the Haem02 project, scientists at the University of Essex are developing an artificial, universal blood substitute that will offer a non-refrigerate...
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Switch discovered that causes mature liver cells to revert back to stem cell-like state

Switch discovered that causes mature liver cells to revert back to stem cell-like state | Longevity science | Scoop.it

Harvard Stem Cell Institute scientists at Boston Children's Hospital have new evidence in mice that it may be possible to repair a chronically diseased liver by forcing mature liver cells to revert back to a stem cell-like state.


The researchers, led by Fernando Camargo, PhD, happened upon this discovery while investigating whether a biochemical cascade called Hippo, which controls how big the liver grows, also affects cell fate. The unexpected answer, published in the journal Cell, is that switching off the Hippo-signaling pathway in mature liver cells generates very high rates of dedifferentiation. This means the cells turn back the clock to become stem-cell like again, thus allowing them to give rise to functional progenitor cells that can regenerate a diseased liver.



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New gene tests may give cancer patients quicker path to treatment

A new way of evaluating tumors may soon help cancer patients identify the underlying genetic link to their disease - and the best possible treatment – all in a single test.


Researchers are set to begin clinical trials using a more comprehensive testing method that looks for all of the known genes that may be active in a tumor



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Sleepless nights raise brain levels of Alzheimer’s protein: study

Sleepless nights raise brain levels of Alzheimer’s protein: study | Longevity science | Scoop.it

After a night of no sleep, even a healthy brain has higher than normal levels of the protein that forms the signature tangles in Alzheimer’s disease, according to a new study from the Netherlands.


“We think normal healthy sleep helps reduce the amount of (amyloid) beta in the brain and if your sleep is disturbed this decrease is prevented,” said the study’s senior author Dr. Jurgen Claassen, from Radboud University Medical Center in Nijmegen.



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Sunshine vitamin D boosts survival chances in bowel cancer: study

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Newly discovered fungus holds clues to stopping superbugs

Newly discovered fungus holds clues to stopping superbugs | Longevity science | Scoop.it
A research team from McMaster University, the University of British Columbia and Cardiff University has discovered a fungus in the soil of the Canadian prov...
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Vascular network bio-printing brings 3D-printed organs one step closer

Vascular network bio-printing brings 3D-printed organs one step closer | Longevity science | Scoop.it
The ability to bio-print tissues and organs could allow us to create custom body parts that could be used for transplants. New research has brought that pos...
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Nanoshell shields foreign enzymes used to starve cancer cells from immune system | KurzweilAI

Nanoshell shields foreign enzymes used to starve cancer cells from immune system | KurzweilAI | Longevity science | Scoop.it
The shell’s pores are too small for the enzyme to escape but big enough for diffusion of amino acids that feed cancer cells in and out of the particle. The
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Muscle-powered bio-bots walk on command | KurzweilAI

Muscle-powered bio-bots walk on command | KurzweilAI | Longevity science | Scoop.it
Tiny walking “bio-bots” are powered by muscle cells and controlled by an electric field (credit: University of Illinois) Engineers at the University of
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A self-powered cardiac pacemaker | KurzweilAI

A self-powered cardiac pacemaker | KurzweilAI | Longevity science | Scoop.it
Artist's impression of a self-powered cardiac pacemaker is enabled by a flexible piezoelectric energy harvester (credit: KAIST) A research team from the
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Google I/O 2014 | watch live here: Ray Kurzweil to present “Biologically Inspired Models of Intelligence” at 3pm PST/ 6pm EST | KurzweilAI

Google I/O 2014 | watch live here: Ray Kurzweil to present “Biologically Inspired Models of Intelligence” at 3pm PST/ 6pm EST | KurzweilAI | Longevity science | Scoop.it
Watch Live | Ray Kurzweil to present: Biologically Inspired Models of Intelligence When | Wednesday, June 25 from 3:00 PM to 3:45 PM PST Live feed
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Bionic pancreas shows promise in trials

Bionic pancreas shows promise in trials | Longevity science | Scoop.it
This February, we first heard about a bionic pancreas that could radically improve the lives of type 1 diabetics. At the time, multi-day trials involving ...
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Asynchronous therapy restores motor control by rewiring of the rat corticospinal tract after stroke

The brain exhibits limited capacity for spontaneous restoration of lost motor functions after stroke. Rehabilitation is the prevailing clinical approach to augment functional recovery, but the scientific basis is poorly understood. Here, we show nearly full recovery of skilled forelimb functions in rats with large strokes when a growth-promoting immunotherapy against a neurite growth–inhibitory protein was applied to boost the sprouting of new fibers, before stabilizing the newly formed circuits by intensive training. In contrast, early high-intensity training during the growth phase destroyed the effect and led to aberrant fiber patterns. Pharmacogenetic experiments identified a subset of corticospinal fibers originating in the intact half of the forebrain, side-switching in the spinal cord to newly innervate the impaired limb and restore skilled motor function.

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3D-bioprinting improved artificial blood vessels | KurzweilAI

3D-bioprinting improved artificial blood vessels | KurzweilAI | Longevity science | Scoop.it
Artificial blood vessels are created using hydrogel constructs that combine advances in 3D bioprinting technology and biomaterials (credit: Khademhosseini
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Nanotech Method Boosts Conventional Cancer Treatments in Pre-Clinical Trial

Nanotech Method Boosts Conventional Cancer Treatments in Pre-Clinical Trial | Longevity science | Scoop.it

The conventional wisdom has it that there’s no silver bullet for treating cancer; the disease simply has too many forms for a one-size-fits-all solution. But there may be, if a recent pre-clinical animal study holds true in humans, a gold bullet.


The findings come from cell biologist Dmitri Lapotko, who leads a Rice University lab called The Nanobubble Lab. Lapotko has found that when colloidal gold nanoparticles inside the body meet with a quick zap from a near-infrared laser, they burst and create a short-lived bubble that can blow up the cells around it.



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Miniature artificial lung could revolutionize cancer research

Miniature artificial lung could revolutionize cancer research | Longevity science | Scoop.it

Researchers at the Fraunhofer Institute for Interfacial Engineering and Biotechnology in Germany have created a miniature artificial lung that has the potential to significantly improve the process of developing treatments for lung cancer. In addition to the possibility of replacing animal trials currently used to test new medications, the "3D-lung" could be used to expand our understanding of how lung cancer spreads to the rest of the body.


With a volume of just half a cubic centimeter, the mini-lung has is made up of human lung cancer cells growing on tissue and is attached to a bioreactor that makes it "breathe" by pumping a nutrient medium through its blood vessels. The model is therefore able to react to medication the same as real human patients.



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