Longevity science
77.8K views | +14 today
Follow
 
Rescooped by Ray and Terry's from Amazing Science
onto Longevity science
Scoop.it!

Researchers trap immune cells in oil-water droplets in hopes of reprogramming them to fight cancer

Researchers trap immune cells in oil-water droplets in hopes of reprogramming them to fight cancer | Longevity science | Scoop.it

Some biologists would like to train patients’ own immune systems to treat diseases such as cancer and autoimmune disorders. They envision programming immune cells to destroy tumor cells or to stop immune system attacks on healthy tissue. Now a team of German researchers reports a method that traps immune cells in microscopic water droplets and exposes the cells to chemical signals that could teach them the difference between friend and foe (J. Am. Chem. Soc., DOI: 10.1021/ja311588c).

 

In our immune systems, T cells play many key roles in preventing disease. They attack invaders such as viruses, help hold the immune system’s memory of past infections, and even prevent other immune cells from attacking the body’s own tissue. Joachim P. Spatz and Ilia Platzman, researchers atMax Planck Institute for Intelligent Systems, in Stuttgart, Germany, study how T cells mature and get trained in a particular task. Many types of T cells interact with antigen-presenting cells, which gather up and display fragments of proteins from viruses, bacteria, and other invaders. Through these cellular interactions, the T cells learn how to identify threats and help the immune system eliminate them.

 

Immunologists believe it will be possible to treat diseases by mimicking this process outside the body. For example, a doctor could isolate a cancer patient’s own T cells, expose the cells to antigens specific to the cancer, and then transplant the cells back to direct the immune system to attack the tumor.

 

Previously developed techniques have exposed T cells to flat, relatively rigid surfaces patterned with antigens. But some researchers think a more optimal approach would involve exposing the T cells to an environment that mimics the three-dimensional curvature and squishiness of real cells.

 

The Max Planck Institute group thought they could create such an environment by enclosing T cells within droplets of water in oil. The inner surface of these droplets contains surfactant molecules that produce a fluid and mechanically soft surface, like that of a cell membrane. The team also developed a way to anchor biomolecules to the surfactants, to mimic the surfaces of antigen-presenting cells.

 

The researchers make the droplets by mixing two streams of liquid in a microfluidic system: an oil solution of the surfactants and a water-based mixture of T cells and culture medium. When the two streams meet, droplets form, with the T-cell mixture trapped inside bubbles of surfactant. The researchers attach gold nanoparticles decorated with antigens to the water-facing end of the surfactants. These particles act like the surfaces of antigen-presenting cells. The droplets can be as small as 10 µm wide, and can hold up to six cells each.

 

In a proof of concept experiment, the scientists coated the gold particles with protein fragments known to interact with T cells. When they looked at the droplets under a microscope, they saw that the T cells adhered to the droplets’ inner surfaces. In droplets made with undecorated gold nanoparticles, the cells floated around randomly within the bubbles.

The cells can survive inside the droplets for five days, after which time Platzman believes they run out of food, since the volume of the droplets is extremely small—just a few picoliters. The researchers next plan to use these droplets to expose T cells to disease-related antigens.


Via Dr. Stefan Gruenwald
more...
Mercor's curator insight, March 5, 2013 12:18 PM

Scooped by Dr. Stefan Gruenwald onto Amazing Science

Philippe Trebaul's curator insight, March 5, 2013 12:32 PM
Poster sur:    TOUT SUR FACEBOOK AVEC PHILIPPE TREBAUL SUR SCOOP.IT  TOUT SUR Pinterest AVEC PHILIPPE TREBAUL SUR SCOOP.IT  TOUS DE GOOGLE PLUS AVEC PHILIPPE TREBAUL SUR SCOOP.IT  Architecture et Urbanisme - Construction Grands Projets de Paris et IDF  REJOIGNEZ-NOUS ET SCOOP.IT Suivez-moi sur SCOOP.IT  MONSTER.FR AVEC PHILIPPE TREBAUL  OPTIMISEUR PRÉSENCE SUR SA LIÉ DANS LA VIA SCOOP.IT ET PHILIPPE TREBAUL  Personal Branding et réseaux professionnels  Philippe TREBAUL sur SCOOP.IT - @ TREBAULPhilippe - MAJORS DE LA FILIERE BTP - WWW. COPTOS.COM  Quel Grand Paris?  Référencement et d'optimisation RANKING  START-UP et Réseaux sociaux - RÉSEAUX START-UP ET SOCIAL - @ TREBAULPhilippe  START-UP ET PROFESSIONNELS Réseaux sociaux - démarrage et réseaux sociaux professionnels - @ TREBAULPhilippe  SOLUTIONS D'IMPRESSION TECHNOLOGIQUES  WEB POUR IMPRIMER AVEC Coptos - www.coptos.com - 01 41 17 40 40 - ISSY-LES-MOULINEAUX   
Cellules immunitaires chercheurs piège huile-eau des gouttelettes dans l'espoir de reprogrammer leur lutte contre le cancer.

"Certains biologistes souhaitez former patients propre système immunitaire pour traiter des maladies telles que le cancer et les troubles auto-immunes.Ils envisagent de programmer des cellules immunitaires à détruire les cellules tumorales ou à arrêter les attaques du système immunitaire sur les tissus sains. Maintenant, une équipe de chercheurs allemands fait état d'une méthode qui piège les cellules immunitaires dans les gouttelettes d'eau microscopiques et expose les cellules à des signaux chimiques qui pourraient leur enseigner la différence entre ami et ennemi (J. Am. Chem Soc, DOI:... 10.1021/ja311588c) .

 

Dans notre système immunitaire, les lymphocytes T jouent de nombreux rôles clés dans la prévention de la maladie. Ils attaquent les envahisseurs tels que les virus, aider à maintenir la mémoire du système immunitaire des infections passées, et même de prévenir d'autres cellules du système immunitaire d'attaquer les propres tissus du corps. Joachim P. Spatz et Ilia Platzman, les chercheurs ATmax Planck Institut des Systèmes Intelligents, à Stuttgart, en Allemagne, étudier comment les cellules T matures et se former dans une tâche particulière. De nombreux types de cellules T interagissent avec les cellules présentatrices d'antigène, qui se réunissent et afficher des fragments de protéines du virus, les bactéries et autres envahisseurs. Grâce à ces interactions cellulaires, les cellules T apprendre à identifier les menaces et aider le système immunitaire à les éliminer.

 

Immunologistes crois qu'il sera possible de traiter les maladies en imitant ce processus en dehors du corps. Par exemple, un médecin peut isoler propres d'un patient cancéreux des cellules T, les cellules exposer à des antigènes spécifiques à la tumeur, puis transplanter les cellules de retour pour diriger le système immunitaire à attaquer la tumeur.

 

Techniques précédemment développés ont exposé des cellules T à des surfaces planes et rigides relativement à motifs avec des antigènes. Mais certains chercheurs pensent une approche plus optimale consisterait à exposer les cellules T à un environnement qui imite la courbure tridimensionnelle et squishiness de véritables cellules.

 

L'Institut Max Planck groupe a pensé qu'ils pouvaient créer un tel environnement en enfermant des cellules T dans les gouttelettes d'eau dans l'huile. La surface interne de ces gouttelettes contient des molécules tensioactives qui produisent un fluide et la surface mécaniquement souple, comme celle d'une membrane cellulaire. L'équipe a également développé une façon d'ancrer biomolécules aux tensioactifs, à imiter les surfaces des cellules présentatrices d'antigène.

 

Les chercheurs font des gouttelettes en mélangeant deux courants de liquide dans un système microfluidique: une solution d'huile et de tensioactifs un mélange à base d'eau des cellules T et un milieu de culture.Lorsque les deux flux se rencontrent, sous forme de gouttelettes, avec le mélange des lymphocytes T piégées à l'intérieur des bulles d'agent tensio-actif. Les chercheurs attachent des nanoparticules d'or décorées avec des antigènes à la fin l'eau face à des tensio-actifs. Ces particules se comportent comme des surfaces de cellules présentatrices d'antigène. Les gouttelettes peuvent être aussi petites que 10 um de large et peut contenir jusqu'à six cellules chacun.

 

Dans une preuve de concept de l'expérience, les scientifiques ont recouvert les particules d'or avec des fragments de protéines connues pour interagir avec les cellules T. Quand ils ont regardé les gouttelettes sous un microscope, ils ont vu que les cellules T adhéré à la surface des gouttelettes internes ». Dans gouttelettes faites avec des nanoparticules d'or non décorés, les cellules flottaient autour de hasard dans les bulles.

Les cellules peuvent survivre à l'intérieur des gouttelettes pendant cinq jours, après quoi Platzman pense qu'ils manquent de nourriture, puisque le volume des gouttelettes est extrêmement petite, juste un peu picolitres. Les chercheurs ont ensuite l'intention d'utiliser ces gouttelettes d'exposer les cellules T aux maladies liées à des antigènes".



Researchers trap immune cells in oil-water droplets in hopes of reprogramming them to fight cancer via @MercorOrg http://sco.lt/...

Longevity science
Live longer in good health and you will have a chance to extend your healthy life even further
Your new post is loading...
Your new post is loading...
Scooped by Ray and Terry's
Scoop.it!

Reinvent Yourself: The Playboy Interview with Ray Kurzweil

Reinvent Yourself: The Playboy Interview with Ray Kurzweil | Longevity science | Scoop.it
Many think author, inventor and data scientist Ray Kurzweil is a prophet for our digital age. A few say he’s completely nuts. Kurzweil, who heads a team of more than 40 as a director of engineering at Google, believes advances in technology and medicine are pushing us toward what he calls the Singularity, a period of profound cultural and evolutionary change in which computers will outthink the brain and allow people—you, me, the guy with the man-bun ahead of you at Starbucks—to live forever. He dates this development at 2045.
more...
No comment yet.
Scooped by Ray and Terry's
Scoop.it!

Caloric Restriction Turns White Fat Brown | The Scientist Magazine®

Caloric Restriction Turns White Fat Brown | The Scientist Magazine® | Longevity science | Scoop.it
In mice, severely restricting caloric intake promotes the transformation of white fat into brown fat, which contains cells that burn energy faster, according to a study published today (August 25) in Cell Metabolism. The innate immune system, researchers from the University of Geneva, Switzerland, and their colleagues reported, mediates this fat cell-transforming effect.

“The paper nicely characterizes this phenomenon,” said Ajay Chawla of the University of California, San Francisco, who was not involved in the work. “And it mechanistically seems to identify a pathway that we had identified.”
more...
No comment yet.
Scooped by Ray and Terry's
Scoop.it!

Google's Verily is developing surgical robots

Google's Verily is developing surgical robots | Longevity science | Scoop.it
Verily Life Sciences - formerly known as Google Life Sciences - has partnered with Johnson & Johnson medical devices subsidiary Ethicon to form Verb Surgical Inc. The new company "aims to develop a comprehensive surgical solutions platform that will incorporate leading-edge robotic capabilities and best-in-class medical device technology for operating room professionals".

Verily CEO Andrew Conrad told WIRED.com that although Verb Surgical represented the Alphabet subsidiary's first partnership, it won't be the last. "We expect to work closely with pharma, biotech, medical device and diagnostic companies, patient advocacy groups, and academic researchers in different ways for a long time to come," he said.
more...
No comment yet.
Scooped by Ray and Terry's
Scoop.it!

Designing new ultrasound imaging tools with Lego-like proteins | KurzweilAI

Designing new ultrasound imaging tools with Lego-like proteins | KurzweilAI | Longevity science | Scoop.it
The next step in ultrasound imaging will let doctors view specific cells and molecules deeper in the body, such as those associated with tumors or bacteria in our gut.

A new study from Caltech outlines how protein engineering techniques might help achieve this milestone. The researchers engineered protein-shelled nanostructures called gas vesicles (which reflect sound waves) to exhibit new properties useful for ultrasound technologies. In the future, these gas vesicles could be administered to a patient to visualize tissues of interest.
more...
No comment yet.
Scooped by Ray and Terry's
Scoop.it!

Ultrasound used to "jump-start" coma patient's brain

Ultrasound used to "jump-start" coma patient's brain | Longevity science | Scoop.it
Researchers at the University of California, Los Angeles (UCLA) have used an ultrasound pulsation treatment to stimulate neurons in the thalamus of a 25-year-old coma patient, leading to a marked improvement in his condition. Once verified with other patients, it's possible that the method could provide a low-cost treatment for severe brain injuries.

The technique used by the research team is called low-intensity focused ultrasound pulsation. Pioneered by UCLA professor Alexander Bystritsky, it involves the use of a small, coffee cup saucer-sized device that produces acoustic energy, which can be targeted at different regions of the brain, exciting tissue. The amount of energy delivered is quite small – less than that of a conventional Doppler ultrasound.
more...
No comment yet.
Scooped by Ray and Terry's
Scoop.it!

Safe, edible battery designed to power ingestible medical devices

Safe, edible battery designed to power ingestible medical devices | Longevity science | Scoop.it
a team of researchers has developed a tiny battery that's entirely non-toxic, providing just enough power for tiny sensing or diagnostic devices to get their jobs done.

According to the team, which is headed by Carnegie Mellon University's Christopher Bettinger, the batteries currently used in ingestible medical devices aren't entirely safe. Being of an "off-the-shelf" nature, such batteries often contain toxic materials that, if trapped inside the body, could cause harm to the patient.
more...
No comment yet.
Scooped by Ray and Terry's
Scoop.it!

Can a short, high-intensity workout replace your longer, more moderate routine?

Can a short, high-intensity workout replace your longer, more moderate routine? | Longevity science | Scoop.it
If you had a choice, would you exercise really hard for one minute or moderately for 45 minutes?

Pressed for time, you probably picked the first option . According to a recent study, the two options — high-intensity interval training (HIIT) and endurance/aerobic training — yield some of the same health and fitness benefits.

How is that possible? Is the rise of HIIT the end of endurance training?

Nope.
more...
No comment yet.
Scooped by Ray and Terry's
Scoop.it!

Tiny particles make a big difference in controlling internal bleeding

Tiny particles make a big difference in controlling internal bleeding | Longevity science | Scoop.it
While there are already ways of controlling bleeding from external wounds, surgery is typically the only option when it comes to stopping internal bleeding. That could be about to change, however, thanks to research being conducted at the University of Maryland, Baltimore County (UMBC). Scientists there are developing injectable nanoparticles, that speed the clotting of blood at internal wound sites.

Each particle contains a molecule that binds with a certain glycoprotein, which is found only on activated platelets.

This means that when administered intravenously (such as would be done at an accident site or on a battlefield), the nanoparticles travel through the bloodstream until they get to a wound site where platelets are already at work
more...
No comment yet.
Scooped by Ray and Terry's
Scoop.it!

What Is Living With An Artificial Pancreas Like? - The Medical Futurist

What Is Living With An Artificial Pancreas Like? - The Medical Futurist | Longevity science | Scoop.it
Traditionally, to monitor blood sugar levels successfully, diabetes patients use insulin pumps and monitors, which send alarms if the glucose levels are too low or too high. More often than not, however, these alarms are quite inefficient. For example, they are often unable to wake up diabetes patients during the night to correct their glucose levels, risking death in their sleep.

This is exactly the reason why diabetes patients have been waiting for a long time for the so-called artificial pancreas – a closed-loop system that constantly measures blood glucose levels, that is able to administer insulin and glucagon in the right amount at the right time – so patients with this chronic illness are able to go to sleep without any worries.
more...
No comment yet.
Scooped by Ray and Terry's
Scoop.it!

Excessive antioxidant use may interfere with cell stress response, study finds

Excessive antioxidant use may interfere with cell stress response, study finds | Longevity science | Scoop.it
Antioxidants’ effects may not be altogether beneficial as a study shows the reactive oxygen species (ROS) molecule that antioxidants are so efficient at eliminating may aid in maintaining health. 
more...
No comment yet.
Scooped by Ray and Terry's
Scoop.it!

Harvard Biologists Just Demonstrated the Most Extensive Reengineering of a Genome Yet

Harvard Biologists Just Demonstrated the Most Extensive Reengineering of a Genome Yet | Longevity science | Scoop.it
Researchers at Harvard Medical School have "radically rewritten" the genome of bacteria E. coli. The team has replaced 7 of its 64 codons (3-letter sequences which correspond usually to a single animo acid.) The lab, led by George Church, had already proven it is possible to recode single amino acids, but this project is the first to introduce so many functional changes to a genome.

Why is this such a big step? Church says it demonstrates the kind of radical reengineering that is possible with emerging genetic engineering tools. This kind of experiment would not even have been possible just a few short years ago.
more...
No comment yet.
Scooped by Ray and Terry's
Scoop.it!

The Oldest of Them All | The Scientist Magazine®

The Oldest of Them All | The Scientist Magazine® | Longevity science | Scoop.it

Greenland sharks roam the cold, dark waters off the of the coasts of northeastern North America, Greenland, and northern Europe. There, they have an unusual talent for staying alive, according to a study published this week (August 11) in Science.

more...
No comment yet.
Scooped by Ray and Terry's
Scoop.it!

Drones take medical samples to the sky in Madagascar

Drones take medical samples to the sky in Madagascar | Longevity science | Scoop.it
Many of the remote villages in the Ifanadiana district of Madagascar aren't linked to the outside world by decent roads. Among other things, this means that it can be very difficult getting medical samples to labs in a timely fashion. That's where a project led by New York-based Stony Brook University comes in. It's been using autonomous drones to get biological samples from those villages to a central testing center, where they can be checked for diseases such as tuberculosis.

The GPS-guided drones were made by project partner Vayu, Inc. They take off and land vertically, like a helicopter, but switch to faster and more efficient fixed-wing flight once they reach altitude.
more...
No comment yet.
Scooped by Ray and Terry's
Scoop.it!

Tasmanian Devils Developing Resistance to Transmissible Cancer | The Scientist Magazine®

Tasmanian Devils Developing Resistance to Transmissible Cancer | The Scientist Magazine® | Longevity science | Scoop.it
During the last 20 years, a contagious cancer has decimated Tasmanian devil (Sarcophilus harrisii) populations. Cancer cells, which are spread by biting, grow deadly tumors on the faces and mouths of the aggressive marsupials. Because devil facial tumor disease (DFTD) has been observed in almost all known populations and is nearly 100 percent fatal, epidemiological models have suggested that the most long-infected populations are facing extinction.

“But they’re currently surviving,” said Andrew Storfer of Washington State University. Now, he and his colleagues have the start of an explanation as to why. In a study published today (August 30) in Nature Communications, Storfer and an international team of researchers reported genomic evidence to suggest that Tasmanian devils are evolving resistance to DFTD.
more...
No comment yet.
Scooped by Ray and Terry's
Scoop.it!

One Antigen Receptor Induces Two T cell Types | The Scientist Magazine®

One Antigen Receptor Induces Two T cell Types | The Scientist Magazine® | Longevity science | Scoop.it
Each newly-formed T cell bears a unique T cell receptor (TCR) that recognizes a particular antigen. But how a given TCR shapes the fate of its cell and that cell’s progeny was largely unknown. Today (August 26), scientists at MIT report in Science Immunology on their discovery that precursor T cells with precisely the same TCR don’t necessarily follow the same developmental path.

“The main take-home message is that T cells with identical specificity . . . can really differentiate into very distinct subtypes of T cell depending on the environment in which they are located,” said mucosal immunologist Daniel Mucida of Rockefeller University in New York who was not involved in the study.
more...
No comment yet.
Scooped by Ray and Terry's
Scoop.it!

Ultrasound jump-starts brain of man in coma | KurzweilAI

Ultrasound jump-starts brain of man in coma | KurzweilAI | Longevity science | Scoop.it
UCLA neurosurgeons used ultrasound to “jump-start” the brain of a 25-year-old man from a coma, and he has made remarkable progress following the treatment.

The technique, called “low-intensity focused ultrasound pulsation” (LIFUP), works non-invasively and without affecting intervening tissues. It excites neurons in the thalamus, an egg-shaped structure that serves as the brain’s central hub for processing information.
more...
No comment yet.
Scooped by Ray and Terry's
Scoop.it!

One big question: Why can't we 3D print functioning organs today?

One big question: Why can't we 3D print functioning organs today? | Longevity science | Scoop.it
We recently reported on an alliance between four companies that has 3D printed heart structures in a weightless environment. As the first installment of our regular new feature where we put one big question to one really smart person, we asked Euguene D. Boland, the chief scientist of Techshot — one of the companies involved in the research — what the single biggest impediment is to having lab-grown organs available right now.

The single biggest impediment is one familiar to many other engineers in their disciplines as well, it's transport. In our case, we are not moving people or cars or airplanes but nutrients and waste to and from every cell in that organ in a tightly orchestrated balance.
more...
No comment yet.
Scooped by Ray and Terry's
Scoop.it!

Face transplant gives ex-firefighter his life back

Face transplant gives ex-firefighter his life back | Longevity science | Scoop.it
One year ago, Patrick Hardison underwent the world's most extensive face transplant at NYU Langone Medical Center in New York. The severely-burned Mississippi firefighter had lost most his facial and head features in the line of duty in 2001, but 15 years later the change is nothing short of dramatic. His doctors call his recovery "unprecedented" and holds promise for the future of similarly injured patients.
more...
No comment yet.
Scooped by Ray and Terry's
Scoop.it!

Infrared instrument lets doctors see through eardrums to spot infections

Infrared instrument lets doctors see through eardrums to spot infections | Longevity science | Scoop.it
In the US, an estimated two million children are incorrectly diagnosed with ear infections every year, and unnecessarily prescribed antibiotics. A new device that switches out conventional visible light observations for shortwave infrared could help, letting doctors peer deeper into the ear than normal. It's designed to be similar to existing otoscopes, meaning doctors won't need dedicated training to use it, and should allow for much more accurate diagnoses.
more...
No comment yet.
Scooped by Ray and Terry's
Scoop.it!

Can a short, high-intensity workout replace your longer, more moderate routine?

Can a short, high-intensity workout replace your longer, more moderate routine? | Longevity science | Scoop.it
If you had a choice, would you exercise really hard for one minute or moderately for 45 minutes?

Pressed for time, you probably picked the first option . According to a recent study, the two options — high-intensity interval training (HIIT) and endurance/aerobic training — yield some of the same health and fitness benefits.

How is that possible? Is the rise of HIIT the end of endurance training?

Nope.
more...
No comment yet.
Scooped by Ray and Terry's
Scoop.it!

PLOS Collections: Article collections published by the Public Library of Science

PLOS Collections: Article collections published by the Public Library of Science | Longevity science | Scoop.it
This Focus Feature led by Rachel Karchin and Ruth Nussinov highlights strategies to predict the phenotypic disease consequences of human germline and somatic variation. The rapid growth in genomic data from large patient cohorts and healthy control populations calls for development of novel, capable and efficient strategies to derive and interpret the phenotypic consequences of germline and somatic variation. The Focus includes network approaches to uncover genotype-phenotype effects in cancer, strategies to bridge the gap between molecular function and the macro level of disease, and in silico methods to predict pathogenic missense variants.
more...
No comment yet.
Scooped by Ray and Terry's
Scoop.it!

The Future of Healthcare Is Arriving—8 Exciting Areas to Watch

The Future of Healthcare Is Arriving—8 Exciting Areas to Watch | Longevity science | Scoop.it
As faculty chair for Medicine and Neuroscience at Singularity University and curator of our annual Exponential Medicine conference (apply to join us this Oct 8–11th), I cross paths with many technologies which have potential healthcare applications. Some are still nascent and not yet close to clinical use (nanobots in our blood, 3D printed organs from your own stem cells), but many others are gaining traction and appearing in our homes, our pockets, and entering clinical settings faster than many might imagine.

There remain significant regulatory, reimbursement, data privacy and adoption challenges (to name a few), but below are eight examples of fast moving, often convergent technologies which are already beginning to be applied effectively to health, prevention, diagnosis, therapy, clinical trials and beyond.
more...
No comment yet.
Scooped by Ray and Terry's
Scoop.it!

Multivitamins Reduce Risk for Heart Disease and Diabetes

Multivitamins Reduce Risk for Heart Disease and Diabetes | Longevity science | Scoop.it
C-reactive protein, or CRP, is a compound produced primarily by the liver in response to acute inflammatory processes, such as bacterial infections. Studies have shown that blood levels of CRP remain chronically elevated, however, in many inflammatory, infectious, and neoplastic (abnormal growth) diseases, including lupus, rheumatoid arthritis, tuberculosis, cancer, diabetes, and heart disease.3

CRP levels are now being used to determine the extent of heart damage during and after heart attacks. One recent study showed that a high CRP level in people who suffer their first heart attack is a strong predictor of future heart attacks, while lower CRP levels suggest less chance of having another heart attack.4 Furthermore, it has now been shown that, even in people who have normal cholesterol levels, high CRP levels can help predict asymptomatic heart disease.5
more...
No comment yet.
Scooped by Ray and Terry's
Scoop.it!

Heat-responsive bandage helps heal wounds

Heat-responsive bandage helps heal wounds | Longevity science | Scoop.it
Over the years, scientists have come up with bandages to detect bedsores before they appear, paint-on bandages that tell doctors how the healing process is coming along, and dressings that change color when an infection is present. Now, a team of researchers from Northwestern University has created a stem cell-attracting bandage with a single purpose in mind – giving the body a helping hand in healing diabetic wounds.
more...
No comment yet.
Scooped by Ray and Terry's
Scoop.it!

Wanted: Transcriptional Regulators | The Scientist Magazine®

Wanted: Transcriptional Regulators | The Scientist Magazine® | Longevity science | Scoop.it
REVEALING RIBOSWITCHES: RNA is isolated from bacteria and tagged with a 3’ adapter, to which a complimentary oligonucleotide binds for reverse transcription and sequencing. Sequence analysis then reveals those transcripts that have been fully transcribed versus those prematurely truncated. The reproducible presence of similarly truncated transcripts for a given gene suggests the presence of a riboswitch in the mRNA.
more...
No comment yet.
Scooped by Ray and Terry's
Scoop.it!

Ultrasonic wireless ‘neural dust’ sensors monitor nerves, muscles in real time | KurzweilAI

Ultrasonic wireless ‘neural dust’ sensors monitor nerves, muscles in real time | KurzweilAI | Longevity science | Scoop.it
University of California, Berkeley engineers have designed and built millimeter-scale device wireless, batteryless “neural dust” sensors and implanted them in muscles and peripheral nerves of rats to make in vivo electrophysiological recordings.

The new technology opens the door to “electroceuticals” — bioelectronic methods to monitor and record wireless electromyogram (EMG) signals from muscle membranes and electroneurogram (ENG) signals from local neuron electrical activity, and to stimulate the immune system, reduce inflammation, and treat disorders such as epilepsy.

The technology could also improve neural control of prosthetics (allowing a paraplegic to control a computer or a robotic arm, for example) by stimulating nerves and muscles directly, instead of requiring implanted wires.
more...
No comment yet.