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Blocking Telomerase Kills Cancer Cells but Provokes Resistance, Progression | MD Anderson Cancer Center

Inhibiting telomerase, an enzyme that rescues malignant cells from destruction by extending the protective caps on the ends of chromosomes, kills tumor cells but also triggers resistance pathways that allow cancer to survive and spread, scientists reported.

 

"Telomerase is overexpressed in many advanced cancers, but assessing its potential as a therapeutic target requires us to understand what it does and how it does it," said senior author Ronald DePinho, M.D., president of The University of Texas MD Anderson Cancer Center.

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Low-Carb Diet Won for Weight-Loss Maintenance

Low-Carb Diet Won for Weight-Loss Maintenance | Longevity science | Scoop.it

 

The striking results of a small clinical trial support the Atkins approach to weight control.

 

That diet plan advocates a diet very low in carbohydrates (sugars and starches), with ample proportions of fat and protein.

 

Unfortunately, Dr. Atkins failed to discriminate among types of fat, which have very different metabolic effects.

 

There’s little doubt that diets too high in omega-6 and saturated fats relative to omega-3 fats – such as the standard American diet – produce unhealthful effects.

 

Two cautions about the new study are in order

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