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Scientists pinpoint how vitamin D may help clear amyloid plaques found in Alzheimer's / UCLA Newsroom

Earlier this year, researchers identified the intracellular mechanisms regulated by vitamin D3 that may help the body clear the brain of amyloid beta, the main component of plaques associated with Alzheimer's disease.

 

Published in the March 6 issue of the Journal of Alzheimer's Disease, the early findings show that vitamin D3 may activate key genes and cellular signaling networks to help stimulate the immune system to clear the amyloid-beta protein.

 

Previous laboratory work by the team demonstrated that specific types of immune cells in Alzheimer's patients may respond to therapy with vitamin D3 and curcumin, a chemical found in turmeric spice, by stimulating the innate immune system to clear amyloid beta. But the researchers didn't know how it worked.

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How vitamin D may help clear amyloid plaques found in Alzheimer’s | KurzweilAI

How vitamin D may help clear amyloid plaques found in Alzheimer’s | KurzweilAI | Longevity science | Scoop.it
UCLA researchers have identified the intracellular mechanisms regulated by vitamin D3 that may help the body clear the brain of amyloid beta, the main...
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Scientists successfully treat Alzheimer’s symptoms in mice

Scientists successfully treat Alzheimer’s symptoms in mice | Longevity science | Scoop.it

By turning off an immune system transmitter in mice with an Alzheimer’s-like condition, scientists have been able to greatly reduce the accumulation of an abnormal protein known as amyloid-ß in the animals’ brains.

 

Previous studies have shown that the protein plays a central role in Alzheimer’s disease. It is hoped that the research may ultimately point the way towards a method of preventing or treating the disease in humans.

 

 

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