Avemar is a naturally fermented wheat germ extract that has been subjected to a great deal of research scrutiny, particularly in the area of cancer treatment. So far it has exhibited positive effects against all forms of cancer cell lines tested.
Much scientific work has been done on fermented wheat germ extract. The manufacturing process was developed in Hungary  by one Professor Máté Hidvégi in Hungary and patented. Its efficacy has been studied by many institutions including UCLA. One thing they all say is that unfermented wheat germ is not as effective as fermented.
Another study "Fermented Wheat Germ Extract (Avemar) in
the Treatment of Cancer and Autoimmune Diseases" also supports that view." See here: http://www.avemarresearch.com/pdf/2C-FermentedWheatGermExtractAvemarintheTreatmentofCancerandAutoimmunediseases.pdf
I am a bit sceptical about such claims. Regular ingestion of wheat germ should itself provide protection from degenerative conditions.
Another review study by Sloan Kettering can be found here: http://www.mskcc.org/cancer-care/herb/wheat-germ-extract
Fermented wheat germ extract (WGE) was developed in the 1990s by Hungarian chemist Mate Hidvegi. It should not be confused with wheat germ oil. WGE is used as a dietary supplement by cancer patients in Hungary to improve quality of life (QoL).
Results from in vitro studies show that WGE has anticancer (1) (2) (3) (4) (5), antimetastatic (6), and immunomodulatory (2) (7) effects. Although it appears to increase estrogen receptor (ER) activity, WGE enhanced efficacy of tamoxifen, an ER antagonist, in ER+ breast cancer cells (8) as well as cisplatin in ovarian cancer cell lines (5). Animal models suggest WGE can reduce cardiovascular symptoms due to chronic hypertension, diabetes, and obesity (9), mitigate symptoms associated with lupus (10), and that its antitumor effect is comparable to other endocrine treatments (11).
Data from pilot studies indicate a beneficial role for WGE in patients with colorectal cancer (12) and in reducing treatment-associated febrile neutropenia in pediatric cancer patients (13). It also prolonged survival of patients with melanoma when used with chemotherapy (14) (15). However, these effects must be confirmed by large-scale, well-designed clinical trials.
Because it potentiates estrogen receptor activity, patients with hormone-sensitive cancers should use WGE with caution.
NUTRITION JOURNAL says: "In conclusion, available data so far, justify the use of FWGE as a non-prescription medical nutriment for cancer patients. Further randomized, controlled and large scale clinical studies are mandatory, to further clarify the value of FWGE as a drug component of future chemotherapy regimens."