"Life, the Universe and Everything" else in Science
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"Life, the Universe and Everything" else in Science
A topic to discuss everything about science. The title is a reference to the book wrote by Douglas Adams.
Curated by Gabriel Wallau
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Reinventing Biostatistics Education for Basic Scientists

Reinventing Biostatistics Education for Basic Scientists | "Life, the Universe and Everything" else in Science | Scoop.it
How is biostatistics education failing to meet the needs of basic scientists, and what can we do to fix this? This Perspective discusses strategies for making biostatistics an integral part of postgraduate and continuing education for basic scientists, ensuring that courses teach the specific skills needed to design, analyze, and critically evaluate basic science research.
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ISCB’s initial reaction to New England Journal of Medicine editorial on data sharing

ISCB’s initial reaction to New England Journal of Medicine editorial on data sharing | "Life, the Universe and Everything" else in Science | Scoop.it
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Pocket DNA sequencers make real-time diagnostics a reality

Pocket DNA sequencers make real-time diagnostics a reality | "Life, the Universe and Everything" else in Science | Scoop.it
Not so long ago, DNA sequencing required massive equipment and lots of time and money. Now, relatively cheap, pocket-sized devices are on the verge of giving real-time sequencing abilities to the masses. These so-called nanopore sequencers, produced so far by a single company, have suffered from poor accuracy. But this month, researchers reported that the instruments passed an important field test, conducting on-the-spot sequencing of viruses isolated from patients during last year's Ebola epidemic in West Africa. In the lab, meanwhile, other researchers are tweaking sample preparation and data analysis to boost the devices' accuracy and speed. Real-time analyses of pathogens and the rest of life are within reach, they say. Ecologists, public health officials, epidemiologists, food safety officials, and many others may reap the benefits. Some researchers predict that one day these sequencers will be in every lab and even in everyone's pocket, like mobile phones.
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Core services: Reward bioinformaticians

Core services: Reward bioinformaticians | "Life, the Universe and Everything" else in Science | Scoop.it
Biological data will continue to pile up unless those who analyse it are recognized as creative collaborators in need of career paths, says Jeffrey Chang.
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Nanopores: a sequencer in your backpack : Nature Methods : Nature Publishing Group

Nanopores: a sequencer in your backpack : Nature Methods : Nature Publishing Group | "Life, the Universe and Everything" else in Science | Scoop.it
stealth
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PLOS Computational Biology: How to Grow a Computational Biology Lab

PLOS Computational Biology: How to Grow a Computational Biology Lab | "Life, the Universe and Everything" else in Science | Scoop.it
Gabriel Wallau's insight:

Nice thoughts to consider!

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Fiscal crisis has Brazilian scientists scrambling

The funding climate is “the worst in 20 years,” says Helena Nader, president of the Brazilian Society for the Advancement of Science (SBPC). Herculano-Houzel is even more pessimistic: “Brazilian science is bankrupt.”
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Genome Biology | Full text | When will ‘open science’ become simply ‘science’?

Open science describes the practice of carrying out scientific research in a completely transparent manner, and making the results of that research available to everyone. Isn’t that just ‘science’?
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PLOS Computational Biology: Ten Simple (Empirical) Rules for Writing Science

PLOS Computational Biology: Ten Simple (Empirical) Rules for Writing Science | "Life, the Universe and Everything" else in Science | Scoop.it
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Measuring the effectiveness of scientific gatekeeping

Measuring the effectiveness of scientific gatekeeping | "Life, the Universe and Everything" else in Science | Scoop.it
Peer review is an institution of enormous importance for the careers of scientists and the content of published science. The decisions of gatekeepers—editors and peer reviewers—legitimize scientific findings, distribute professional rewards, and influence future research. However, appropriate data to gauge the quality of gatekeeper decision-making in science has rarely been made publicly available. Our research tracks the popularity of rejected and accepted manuscripts at three elite medical journals. We found that editors and reviewers generally made good decisions regarding which manuscripts to promote and reject. However, many highly cited articles were surprisingly rejected. Our research suggests that evaluative strategies that increase the mean quality of published science may also increase the risk of rejecting unconventional or outstanding work.
Gabriel Wallau's insight:

Nice piece of paper!!

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PLOS Computational Biology: Applying, Evaluating and Refining Bioinformatics Core Competencies (An Update from the Curriculum Task Force of ISCB’s Education Committee)

PLOS Computational Biology: Applying, Evaluating and Refining Bioinformatics Core Competencies (An Update from the Curriculum Task Force of ISCB’s Education Committee) | "Life, the Universe and Everything" else in Science | Scoop.it
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Who's downloading pirated papers? Everyone

Who's downloading pirated papers? Everyone | "Life, the Universe and Everything" else in Science | Scoop.it
An exclusive look at data from the controversial web site Sci-Hub reveals that the whole world, both poor and rich, is reading pirated research papers.
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Genome Biology

Genome Biology | "Life, the Universe and Everything" else in Science | Scoop.it
Generating ever-greater amounts of sequence information will become futile if those data hit a bottleneck during processing and analysis
Gabriel Wallau's insight:
"Generating ever-greater amounts of sequence information will become futile if those data hit a bottleneck during processing and analysis" nice summarizing sentence!
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Public Data Archiving in Ecology and Evolution: How Well Are We Doing?

Public Data Archiving in Ecology and Evolution: How Well Are We Doing? | "Life, the Universe and Everything" else in Science | Scoop.it
Careful scrutiny of one hundred studies in journals that mandate data archival reveals that over half do not comply with their journal’s data policy.
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How do I get to peer review a paper? A PhD student asks… - Moore - 2015 - BioEssays - Wiley Online Library

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Portal Fiocruz - PE - Home Page

Portal Fiocruz - PE Centro de Pesquisa Aggeu Magalhães

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PLOS Computational Biology: Ten Simple Rules for a Computational Biologist’s Laboratory Notebook

PLOS Computational Biology: Ten Simple Rules for a Computational Biologist’s Laboratory Notebook | "Life, the Universe and Everything" else in Science | Scoop.it
One of the major hurdles I face as the head of a computational biology laboratory is convincing my research team—particularly those pursuing exclusively mathematical and computational modeling—that they need to keep a laboratory notebook. There seems to be a misconception in the computational biology community that a lab notebook is only useful for recording experimental protocols and their results. A lab notebook is much more than that. It is an organizational tool and memory aid, which serves as the primary record of scientific research and activity for all scientists. It also serves as a legal record of ownership of the ideas and results obtained by a scientist. Here, I present the best practices (summarized as ten rules) for keeping a lab notebook in computational biology, for scientists pursuing exclusively “dry” research.
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The Question of Data Integrity in Article-Level Metrics

The Question of Data Integrity in Article-Level Metrics | "Life, the Universe and Everything" else in Science | Scoop.it
Article-level metric (ALM) data need to be secure and reliable if they are to be trusted and used by all. This Perspective explores the different approaches taken by two organizations to establish ALM data integrity.
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PLOS Computational Biology: Ten Simple Rules for Reducing Overoptimistic Reporting in Methodological Computational Research

PLOS Computational Biology: Ten Simple Rules for Reducing Overoptimistic Reporting in Methodological Computational Research | "Life, the Universe and Everything" else in Science | Scoop.it
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