Humans are the only animals that can imagine the future. That’s great when it comes to figuring out what makes us happy. But what about those sleepless nights filled with anxiety? Joseph LeDoux has spent 30 years studying the biological underpinnings of memory and emotion, especially the mechanisms of fear. He has been doing research on animals, primarily rats, to understand pathological fear and anxiety in humans. A Henry and Lucy Moses Professor of Science and professor of neural science and psychology at New York University, his concentration on the amygdala, that almond-shaped structure in the brain’s temporal lobe having to do with emotional behavior, has also spawned a rock band called the Amygdaloids, with himself and three of his scientific colleagues.