This coast-to-coast race takes running relay teams from the Adriatic Sea to the Tyrrhenian Sea, passing through Italy’s stunning vineyards and olive tree groves along the way. The route follows the backroads through Marche, Umbria and Tuscany and takes 4 days to complete.
Each runner has to tackle 55 miles each day, with a new running taking over each day for the team. The post-run meals are definitely a highlight, as is the scenery and the friendly atmosphere among runners. (source)