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New nanotechnology method sneaks drugs into cancer cells before triggering release

New nanotechnology method sneaks drugs into cancer cells before triggering release | Interesting Innovation | Scoop.it
New nanotechnology method sneaks drugs into cancer cells before triggering release

 

Biomedical engineering researchers have developed a nanotechnology anti-cancer drug delivery method that essentially smuggles the drug into a cancer cell before triggering its release ("Enhanced Anticancer Efficacy by ATP-Mediated Liposomal Drug Delivery"). The method can be likened to keeping a cancer-killing bomb and its detonator separate until they are inside a cancer cell, where they then combine to destroy the cell.



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Gust MEES's curator insight, May 9, 2014 8:47 AM

Biomedical engineering researchers have developed a nanotechnology anti-cancer drug delivery method that essentially smuggles the drug into a cancer cell before triggering its release ("Enhanced Anticancer Efficacy by ATP-Mediated Liposomal Drug Delivery"). The method can be likened to keeping a cancer-killing bomb and its detonator separate until they are inside a cancer cell, where they then combine to destroy the cell.


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Brain-penetrating nanoparticle attacks deadly tumors

Brain-penetrating nanoparticle attacks deadly tumors | Interesting Innovation | Scoop.it
Brain-penetrating nanoparticle attacks deadly tumors

 

(Nanowerk News) Scientists have developed a new approach for treating a deadly brain cancer that strikes 15,000 in the United States annually and for which there is no effective long-term therapy. The researchers, from Yale and Johns Hopkins, have shown that the approach extends the lives of laboratory animals and are preparing to seek government approval for a human clinical trial.

 

“We wanted to make a system that would penetrate into the brain and deliver drugs to a greater volume of tissue,” said Mark Saltzman, a biomedical engineer at Yale and principal investigator of the research. “Drugs have to get to tumor cells in order to work, and they have to be the right drugs.



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Nanotech researchers prove two-step method for potential pancreatic cancer treatment

Nanotech researchers prove two-step method for potential pancreatic cancer treatment | Interesting Innovation | Scoop.it
A new method of microscopic drug delivery that could greatly improve the treatment of deadly pancreatic cancer has been proven to work in mice at UCLA's Jonsson Comprehensive Cancer Center.

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The Nanodoctor Will See You: Tiny Particles May Help Fight Disease

The Nanodoctor Will See You: Tiny Particles May Help Fight Disease | Interesting Innovation | Scoop.it
Researchers are designing tiny particles to act as medicine.

 

The particles are coated with waterlike molecules that allow them to travel inside the body without being detected by the immune system, Farokhzad said. Their surfaces contain molecules that provide them with a "GPS" to seek out abnormal cancer cells.

 

Once they find a cancer cell, the particles stick, and like a Trojan horse, the cancer cells take them inside where they can release medicine that's toxic to the cell, Farokhzad said. [Watch the World Science Festival Live.]

 

In a study published last year in Science Translational Medicine, Farokhzad and colleagues showed that, in people, the nanoparticles delivered a much higher dose of medicine to cancer cells than to other cells in the body. Follow-up studies will test the effectiveness of the drug at treating tumors.

 


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Gust MEES's curator insight, June 2, 2013 6:00 PM

 

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http://www.scoop.it/t/21st-century-innovative-technologies-and-developments/?tag=Nano

 

Richard Robert's comment, June 19, 2013 3:11 AM
Thanks for sharing, this is a good piece. Apart from nanoparticles, nanorobots are also on the rise in cancerology: http://www.paristechreview.com/2013/04/26/cancer-treatment/
Djami-10's curator insight, July 6, 2013 5:17 AM

very interesting progress