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Institut Pasteur de Tunis-معهد باستور تونس
L’Institut Pasteur de Tunis (IPT) est un établissement public de santé et de recherche scientifique.







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Deanna Church on the Reference Genome Past, Present and Future - Bio-IT World

Deanna Church on the Reference Genome Past, Present and Future - Bio-IT World | Institut Pasteur de Tunis-معهد باستور تونس | Scoop.it
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33rd Square | Researchers Map 3D Structure of The Telomerase Enzyme

33rd Square | Researchers Map 3D Structure of The Telomerase Enzyme | Institut Pasteur de Tunis-معهد باستور تونس | Scoop.it
Researchers from UCLA and UC Berkeley have, for the first time ever, solved the puzzle of how the various components of an entire telomerase enzyme complex fit together and function in a three-dimensional structure.
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Next Gen Sequencing Reveals Transposable Elements Can Re-wire Gene Regulatory Networks

Next Gen Sequencing Reveals Transposable Elements Can Re-wire Gene Regulatory Networks | Institut Pasteur de Tunis-معهد باستور تونس | Scoop.it
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Les fourmis sont des carriéristes

Les fourmis sont des carriéristes | Institut Pasteur de Tunis-معهد باستور تونس | Scoop.it
Les insectes de plusieurs colonies pistés au moyen de code-barres ont révélés des comportements sociaux et des interactions surprenantes.
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PLOS Genetics: Genetic and Genomic Architecture of the Evolution of Resistance to Antifungal Drug Combinations

PLOS Genetics: Genetic and Genomic Architecture of the Evolution of Resistance to Antifungal Drug Combinations | Institut Pasteur de Tunis-معهد باستور تونس | Scoop.it

Here, we evolved experimental populations of the model yeast Saccharomyces cerevisiae and the leading human fungal pathogen Candida albicans with azole and an inhibitor of Hsp90, geldanamycin, or calcineurin, FK506. To recapitulate a clinical context where Hsp90 or calcineurin inhibitors could be utilized in combination with azoles to render resistant pathogens responsive to treatment, the evolution experiment was initiated with strains that are resistant to azoles in a manner that depends on Hsp90 and calcineurin. Of the 290 lineages initiated, most went extinct, yet 14 evolved resistance to the drug combination. Drug target mutations that conferred resistance to geldanamycin or FK506 were identified and validated in five evolved lineages.


Via Bradford Condon
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Savoirs Partagés : Entomologie médicale

Savoirs Partagés "Entomologie médicale" avec Didier FONTENILLE. Une émission produite par l'IRD Audiovisuel, Cinaps TV et Brigitte SURUGUE, animée par Antoine SPIRE.

 


Via Bernadette Cassel
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Dengue Viral Fusion

Dengue was created for Irene Bosch, Ph.D. at University of Massachusetts and Yorgo Modis, Ph.D. from Yale University. This animation was an educational proje...

Via Ken Yaw Agyeman-Badu
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Conférerence à l'IPT, jeudi 25 avril 2013 (10h00) "Microbial Identification for the 21st Century" par le Dr Tabisam Khan

Conférerence à l'IPT, jeudi 25 avril 2013 (10h00) "Microbial Identification for the 21st Century" par le Dr Tabisam Khan | Institut Pasteur de Tunis-معهد باستور تونس | Scoop.it
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Virology Journal | Abstract | Do viruses require the cytoskeleton?

It is generally thought that viruses require the cytoskeleton during their replication cycle.
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Weeding out ineffective biocontrol agents

Weeding out ineffective biocontrol agents | Institut Pasteur de Tunis-معهد باستور تونس | Scoop.it
Biocontrol programs use an invasive plant's natural enemies (insects and pathogens) to reduce its population. Most biocontrol programs combine many different enemies.
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Réviser "L'immunologie" extrait du hors-série Le Monde

Réviser "L'immunologie" extrait du hors-série Le Monde | Institut Pasteur de Tunis-معهد باستور تونس | Scoop.it
Voici les scans du même Hors-Série d'avril 2013... Pour vous donner envie de l'acheter car désormais je ne scanne plus rien afin de respecter les droits d'auteur ! D'ailleurs si vous souhaitez vous...
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WHO | Behind the Essential Medicines List

WHO | Behind the Essential Medicines List | Institut Pasteur de Tunis-معهد باستور تونس | Scoop.it
WHO’s Model Essential Medicines List provides an internationally recognizable set of selected medicines to help countries choose how to treat their priority health needs.
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Gene Duplication Is Infrequent in the Recent Evolutionary History of RNA Viruses

Gene Duplication Is Infrequent in the Recent Evolutionary History of RNA Viruses | Institut Pasteur de Tunis-معهد باستور تونس | Scoop.it
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The Structure of Industrial Revolutions | Oscillator, Scientific American Blog Network

The Structure of Industrial Revolutions | Oscillator, Scientific American Blog Network | Institut Pasteur de Tunis-معهد باستور تونس | Scoop.it
This post originally appeared on the brand new Synthetic Biology Engineering Research Center (Synberc) Blog. Check it out for other new posts by Jay Keasling and ...
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Discovery paves the way for ultra fast high resolution imaging in real time

Discovery paves the way for ultra fast high resolution imaging in real time | Institut Pasteur de Tunis-معهد باستور تونس | Scoop.it
Melbourne, Australia (SPX) Apr 22, 2013 - In work published in Nature Communications, researchers from the University of Melbourne and the ARC Centre for Excellence in Coherent Xray Science have demonstrated that ultra short durations of el...
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Four-strand DNA structure found in cells

Four-strand DNA structure found in cells | Institut Pasteur de Tunis-معهد باستور تونس | Scoop.it
Unusual nucleic-acid structure may have role in regulating some genes.
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Virus H7N9 : sa carte d?identité génétique préoccupe les experts

Virus H7N9 : sa carte d?identité génétique préoccupe les experts | Institut Pasteur de Tunis-معهد باستور تونس | Scoop.it
H7N9 contient des mutations suscitant l’inquiétude des chercheurs.
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Bioengineers Build Open Source Language for Programming Cells

Bioengineers Build Open Source Language for Programming Cells | Institut Pasteur de Tunis-معهد باستور تونس | Scoop.it

Via Socrates Logos
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Socrates Logos's curator insight, April 20, 2013 2:53 PM

BY DANIELA HERNANDEZ

"Drew Endy wants to build a programming language for the body.

Endy is the co-director of the International Open Facility Advancing Biotechnology — BIOFAB, for short — where he’s part of a team that’s developing a language that will use genetic data to actually program biological cells. That may seem like the stuff of science fiction, but the project is already underway, and the team intends to open source the language, so that other scientists can use it and modify it and perfect it.

The effort is part of a sweeping movement to grab hold of our genetic data and directly improve the way our bodies behave — a process known as bioengineering. With the Supreme Court exploring whether genes can be patented, the bioengineering world is at crossroads, but scientists like Endy continue to push this technology forward.

Genes contain information that defines the way our cells function, and some parts of the genome express themselves in much the same way across different types of cells and organisms. This would allow Endy and his team to build a language scientists could use to carefully engineer gene expression – what they call “the layer between the genome and all the dynamic processes of life.”...."

http://bit.ly/11wYtiC

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Happy Birthday, Human Genome Project - Benefits still at the 'tip of the iceberg'

Researchers look forward to the next decade of medical innovations as they celebrate the 10th anniversary of the completion of the Human Genome Project. New medications for rare genetic conditions. Breakthroughs in disease research. Targeted cancer therapy. Revolutionary promises for public health.


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Cancer du col de l’utérus : la vaccination recommandée pour les jeunes filles dès 11 ans

Cancer du col de l’utérus : la vaccination recommandée pour les jeunes filles dès 11 ans | Institut Pasteur de Tunis-معهد باستور تونس | Scoop.it

L’Institut National Du Cancer (INCa) lance une campagne d’information au mois de juin sur la prévention du cancer du col de l’utérus. Une campagne qui met l’accent sur deux leviers : la vaccination, désormais recommandée pour les jeunes filles, dès 11 ans, et un dépistage par frottis tous les 3 ans, pour les femmes de 25 à 65 ans, qu’elles soient vaccinées ou non.

Jusqu’alors recommandée à partir de 14 ans, la vaccination est, depuis avril 2013, recommandée pour toutes les jeunes filles âgées de 11 à 14 ans ou, en rattrapage, jusqu’à l’âge de 19 ans révolus. La vaccination ne protège pas contre tous les types de HPV, à l’origine des cancers du col de l’utérus. « Elle ne dispense donc pas d’un dépistage régulier par frottis, recommandé, tous les 3 ans, à toutes les femmes à partir de 25 ans et jusqu’à 65 ans, qu’elles soient vaccinées ou non », explique l’INCa.


Via L'Info Autrement
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Des nanoéponges pour absorber les toxines

Des nanoéponges pour absorber les toxines | Institut Pasteur de Tunis-معهد باستور تونس | Scoop.it
Une équipe de San Diego a mis au point des particules nanométriques qui, injectées dans la circulation sanguine, neutraliseraient une vaste famille de toxines.
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Electronic zippers control DNA strands

Electronic zippers control DNA strands | Institut Pasteur de Tunis-معهد باستور تونس | Scoop.it
A research team from NPL and the University of Edinburgh have invented a new way to zip and unzip DNA strands using electrochemistry.
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Parasite Inspires Surgical Patch

Parasite Inspires Surgical Patch | Institut Pasteur de Tunis-معهد باستور تونس | Scoop.it

By mimicking a technique used by an intestinal parasite of fish, researchers have developed a flexible patch studded with microneedles that holds skin grafts in place more strongly than surgical staples do. After burrowing into the walls of a fish's intestines, the spiny-headed worm Pomphorhynchus laevis inflates its proboscis to better embed itself in the soft tissue. In the new patch (sample shown in main image), the stiff polystyrene core of the 700-micrometer-tall needles (inset) penetrates the tissue; then a thin hydrogel coating on the tip of each needle—a coating based on the material in disposable diapers that expands when it gets wet—swells to help anchor the patch in place. In tests using skin grafts, adhesion strength of the patch was more than three times higher than surgical staples, the researchers report online today in Nature Communications. Because the patch doesn't depend on chemical adhesives for its gripping power, there's less chance for patients to have an allergic reaction. And because the microneedles are about one-quarter the length of typical surgical staples, the patches cause less tissue damage when they're removed, the researchers contend. Besides holding grafts in place, the patch could be used to hold the sides of a wound or an incision together—even, in theory, ones inside the body if a slowly dissolving version of the patch can be developed. Moreover, the researchers say, the hydrogel coating holds promise as a way to deliver proteins, drugs, or other therapeutic substances to patients.


Via Dr. Stefan Gruenwald
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The Comunicating Science team's curator insight, April 18, 2013 9:20 PM

As someone who has sat and removed surgical staples this is a nice piece of technology

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Veille scientifique et web 2.0 : une carte mentale

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Institut Pasteur - origines différences - Lluis-Quintana-Murci

Au fil de son évolution, l'Homme s'est adapté à différents environnements (climatiques, nutritionnels, pathogéniques, etc.), faisant ainsi évoluer son génome...
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