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Ancient DNA reveals Europe's dynamic genetic history

Ancient DNA reveals Europe's dynamic genetic history | Institut Pasteur de Tunis-معهد باستور تونس | Scoop.it
Ancient DNA recovered from a series of skeletons in central Germany up to 7500 years old has been used to reconstruct the first detailed genetic history of modern Europe.
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Institut Pasteur de Tunis-معهد باستور تونس
L’Institut Pasteur de Tunis (IPT) est un établissement public de santé et de recherche scientifique.







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Prévention et riposte contre la Fièvre à virus Ebola : Rapport de l'Observatoire National des Maladies Nouvelles et Emérgentes

Prévention et riposte contre la Fièvre à virus Ebola : Rapport de l'Observatoire National des Maladies Nouvelles et Emérgentes | Institut Pasteur de Tunis-معهد باستور تونس | Scoop.it

L'Observatoire National des Maladies Nouvelles et émérgentes a mis en ligne sur son site web http://www.onmne.tn, un document informatif détaillé sur l'épidémie de Fièvre Ebola localisée actuellement dans des pays comme la Guinée, la Sierra Léone, le Libéria, le Nigéria.

Ce document précise notamment les mesures mises en place pour lutter contre cette épidémie et les bonnes conduites à tenir.

Consulter le document "Prévention et riposte contre la Fièvre à virus Ebola"

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Research Tools: “33 Tips to Maximize Articles' Citation Frequency ...

Research Tools: “33 Tips to Maximize Articles' Citation Frequency ... | Institut Pasteur de Tunis-معهد باستور تونس | Scoop.it
Nader Ale Ebrahim's academic activities. Home · About · Images · Journal Papers · Publications · Scoop.it · Uncategorized. Research Tools: “33 Tips to Maximize Articles' Citation Frequency … July 1, 2014 … Tool Box”.

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Scientific symposium “Consanguinity and hereditary rare diseases” in Tunis – 22-27 September 2014 and Genomedika Final Conference 29-30 september 2014

To increase awareness on the importance of studying rare diseases in developing countries, especially in the Mediterranean and the Middle East regions, a scientific symposium will take place in Tunis, from 22 to 27 September. This meeting is supported by the French Foundation for rare diseases (Fondation maladies rares) and TWAS (The World Academy of Sciences).The symposium will include keynote speeches on cutting edge strategies for rare diseases investigation in consanguineous populations. It will also include round tables on the challenges encountered in rare diseases investigation in the region and perspectives for collaboration in this field. In addition, hands-on training would be organised on bioinformatics and statistical analysis of data generated using high throughput genotyping and next generation sequencing technologies.This event is the opportunity to exchange information and share expertise. It is intended to have not only a scientific and educational dimension but it will be also the occasion to strengthen existing collaborations, which are mainly bilateral, and to create a multidisciplinary regional network on rare diseases investigation.Contact: Dr Sonia Abdelhak - sonia.abdelhak@pasteur.rns.tn This email address is being protected from spambots. You need JavaScript enabled to view it.  This event will be followed by the Genomedika final conference which will take place on September 29-30, 2014, during which, project participants will give a return on their outcomes.
Via Genomedika
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Mohamed El Ayeb obtient le Prix du Président de la République pour la recherche scientifique et la technologie

Mohamed El Ayeb obtient le Prix du Président de la République pour la recherche scientifique et la technologie | Institut Pasteur de Tunis-معهد باستور تونس | Scoop.it
Le Pr Mohamed El Ayeb, chef du laboratoire de recherche Venins et biomolécules thérapeutiques a obtenu à l’occasion de la Journée du Savoir célébrée le 23 juillet 2014, le Prix du Président de la République pour la recherche scientifique et la technologie, dans le secteur de la biotechnologie en rapport avec la santé, l’agriculture, l’environnement et l’industrie.

 

Accordé aux chercheurs et aux compétences qui se distinguent par leurs créations scientifiques ou par leurs innovations technologiques le Prix du Président de la République pour la recherche scientifique et la technologie souligne aussi l’importance donnée à la formation par la Recherche ainsi que l’ouverture sur le monde socio-économique.

 

Ce prix obtenu par notre collègue vient récompenser une carrière scientifique riche et exemplaire au sein de l’Institut Pasteur de Tunis.

 

Mohamed El Ayeb, l’un des premiers biologistes recrutés à la fin des années 80 à l’IPT, est également membre du conseil scientifique de l'Académie Tunisienne des Sciences, des Lettres et des Arts Beit Al Hikma.

Félicitations cher collègue !

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Jade Le Maître : « Les réseaux sociaux sont un outil de veille et de collaboration en sciences »

Jade Le Maître : « Les réseaux sociaux sont un outil de veille et de collaboration en sciences » | Institut Pasteur de Tunis-معهد باستور تونس | Scoop.it
RT @CNRSMip: bon article "science et partage" http://t.co/NHISfXgeRd cc @Aratta @audrey_bardon @Leauickque

Via Denis Hudrisier
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Painful Mosquito-Borne Disease Now Infecting More Than 350,000 People In The Americas

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In Gene Sequencing Treatment for Leukemia, Glimpses of the Future

In Gene Sequencing Treatment for Leukemia, Glimpses of the Future | Institut Pasteur de Tunis-معهد باستور تونس | Scoop.it
A novel method known as whole genome sequencing focuses on genes that drive a cancer, not the tissues or organ where it originates.
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Bacteria: A day in the life

Bacteria: A day in the life | Institut Pasteur de Tunis-معهد باستور تونس | Scoop.it
MIT study finds ocean bacteria follow predictable patterns of daily activity.
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Cooperating with the future

Overexploitation of renewable resources today has a high cost on the welfare of future generations. Unlike in other public goods games, however, future generations cannot reciprocate actions made today. What mechanisms can maintain cooperation with the future? To answer this question, we devise a new experimental paradigm, the /`Intergenerational Goods Game/'. A line-up of successive groups (generations) can each either extract a resource to exhaustion or leave something for the next group. Exhausting the resource maximizes the payoff for the present generation, but leaves all future generations empty-handed. Here we show that the resource is almost always destroyed if extraction decisions are made individually. This failure to cooperate with the future is driven primarily by a minority of individuals who extract far more than what is sustainable. In contrast, when extractions are democratically decided by vote, the resource is consistently sustained. Voting is effective for two reasons. First, it allows a majority of cooperators to restrain defectors. Second, it reassures conditional cooperators that their efforts are not futile. Voting, however, only promotes sustainability if it is binding for all involved. Our results have implications for policy interventions designed to sustain intergenerational public goods.

 

Cooperating with the future
Oliver P. Hauser, David G. Rand, Alexander Peysakhovich & Martin A. Nowak

Nature 511, 220–223 (10 July 2014) http://dx.doi.org/10.1038/nature13530


Via Complexity Digest
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Tom Cockburn's curator insight, July 31, 3:26 AM

Optimistic,in lab at least?

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Rapport 2013 de l'Institut Pasteur de Tunis

Rapport d'activité de l'année 2013 de l'Institut Pasteur de Tunis
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Ramadan : comment tenir sans manger pendant les jours les plus longs de l'année ?

Ramadan : comment tenir sans manger pendant les jours les plus longs de l'année ? | Institut Pasteur de Tunis-معهد باستور تونس | Scoop.it
Cette année, le Ramadan demandera des périodes de jeûne particulièrement longues. Francetv info répertorie 5 conseils pratiques pour ne pas trop souffrir en attendant les festivités du soir.  

Via L'Info Autrement
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CYP1B1 Gene Mutations Causing Primary Congenital Glaucoma in Tunisia - Bouyacoub Y. - 2014 - Annals of Human Genetics - Wiley Online Library

CYP1B1 Gene Mutations Causing Primary Congenital Glaucoma in Tunisia - Bouyacoub Y. - 2014 - Annals of Human Genetics - Wiley Online Library | Institut Pasteur de Tunis-معهد باستور تونس | Scoop.it
Keywords:c.535delG;CYP1B1 gene;primary congenital glaucoma;p.G61E;proto-haplotype;Tunisian patientsSummary

Primary congenital glaucoma (PCG) is responsible for a significant proportion of childhood blindness in Tunisia. Early prevention based on genetic diagnosis is therefore required. This study sought to determine the frequency of CYP1B1 (cytochrome P450, family 1, subfamily B, polypeptide 1) mutations in 18 PCG patients, recruited from Central and Southern of Tunisia.

Genomic DNA was extracted and the coding regions of CYP1B1 were analysed by direct sequencing. A phylogenetic network of CYP1B1 haplotypes was drawn using the median-joining algorithm.

Sequence analysis revealed a “tetra-allelic mutation” (two novel mutations, p.F231I and p.P437A in the homozygous state) in one patient. The healthy members of his family carried those variations on the same allele. Two previously described mutations p.G61E and c.535delG were also identified in the homozygous state in seven and two probands, respectively. Seven single-nucleotide polymorphisms were identified and used to generate haplotypes.

Our results showed that the CYP1B1 mutations were present in 55% of Tunisian PCG patients’ alleles. Haplotype analysis allowed us to define the proto-haplotype and to confirm historical migratory flows. Establishment of PCG genetic aetiology in Tunisia will improve genetic diagnosis and counselling.

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Présentations LCMS-Agilent,24 juin 2014 à 9h00, amphithéâtre du bâtiment Recherche

Présentations LCMS-Agilent,24 juin 2014 à 9h00, amphithéâtre du bâtiment Recherche | Institut Pasteur de Tunis-معهد باستور تونس | Scoop.it

Le 24 juin 2014, le Dr. Georges Touspras de la société Agilent Technologie proposera les conférences suivantes à 9h00

9h00 – 9h45Agilent’s Tandem Mass spectrometry solutions9h45 – 10h30
Proteins discovery workflows  – Nano HPLC  Chip Cube  QTOF system10h30 – 10h45 Pause Café10h45 – 11h15 Proteins and Peptides Quantification  using  QQQ 11h15 – 11h45 Profiling and Biomarkers  discovery – Metabolomics  studies11h45 – 12h15 What does Ion Mobility Bring to Mass Spectrometry Questions et Discussions  ouvertes avec les intervenants 



Ces conférences sont en accès libre.

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Concours National de l’Innovation

Concours National de l’Innovation | Institut Pasteur de Tunis-معهد باستور تونس | Scoop.it

 

L’Agence de Promotion de l’Industrie et de l’Innovation, API, avec le soutien du Projet d’Appui au Système de Recherche et d’Innovation" PASRI" financé par l’Union européenne, lance le Concours National de l’Innovation.
Conçu et réalisé dans le cadre de la volonté de l’Etat et de tous les acteurs et intervenants économiques de promouvoir et de diffuser la culture de l’innovation en tant que vecteur de développement économique, ce concours est organisé en partenariat avec l’Agence Nationale de la Promotion de la Recherche scientifique, ANPR, le Ministère de l’Enseignement Supérieur, de la Recherche Scientifique et des Technologies de l’Information et de la Communication, le Ministère de l’Industrie, de l’Energie et des Mines, l’UTICA et la CONECT.

 

Date limite de dépôt des candidatures: 29 Août 2014

 

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GRIN - Visibility and Citation Impact

GRIN - Visibility and Citation Impact | Institut Pasteur de Tunis-معهد باستور تونس | Scoop.it
Visibility and Citation Impact - Nader Ale Ebrahim et al. - Academic Paper - Education - Reading Instruction - Education - Reading Instruction - Publish your thesis, dissertation, term paper or essay

Via Nader Ale Ebrahim
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Introduction à la statistique avec R

Introduction à la statistique avec R | Institut Pasteur de Tunis-معهد باستور تونس | Scoop.it
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Social media for scientists

Social media are important for scientists to let the world know whet they are doing. It is essential to communicate with scientists and the general public. It …

Via Hichem Ben Hassine
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Institut Pasteur de Tunis - معهد باستور تونس‎'s comment, July 16, 5:42 AM
You're right. Scoop it should have been added in this presentation. Thanks
Gilbert Faure au nom de l'ASSIM's comment, July 16, 6:17 AM
I commented on slideshare
Institut Pasteur de Tunis - معهد باستور تونس‎'s comment, July 16, 6:20 AM
Thanks
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Do researchers prefer more or less restrictive Creative Commons licenses? | Open Science

Do researchers prefer more or less restrictive Creative Commons licenses? | Open Science | Institut Pasteur de Tunis-معهد باستور تونس | Scoop.it
Some Open Access advovates opt for permissive licensing of scientific works in particular for Creative Commons Attribution license, however...

Via Nader Ale Ebrahim
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Friends Are the Family You Choose: Genome-Wide Analysis Reveals Genetic Similarities Among Friends

Friends Are the Family You Choose: Genome-Wide Analysis Reveals Genetic Similarities Among Friends | Institut Pasteur de Tunis-معهد باستور تونس | Scoop.it
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Chikungunya : les Antilles se mobilisent pour faire face à l'épidémie

Chikungunya : les Antilles se mobilisent pour faire face à l'épidémie | Institut Pasteur de Tunis-معهد باستور تونس | Scoop.it
À la veille de la venue de la ministre de la Santé, Marisol Touraine, les Antilles multiplient les actions de sensiblisation des populations pour endiguer l’épidémie.
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Why Communicating With Patients Using Social Media is a Good Idea

Why Communicating With Patients Using Social Media is a Good Idea | Institut Pasteur de Tunis-معهد باستور تونس | Scoop.it

Most companies have a Facebook or twitter page; medical practices should also communicate with their patients using social media. The medical field has been less proactive when it comes to maintaining a social media presence. It’s an effective way to make sure your practice is branded in your specific field of expertise. Don’t overlook social media as a great way to communicate with your patients. People are looking for doctors who care and take time to get know their patients, this is where social media can shine.

Communicating with patients using social media creates a personal connection without having an appointment. Create a discussion on your facebook page where people can go to get answers to common questions regarding scheduling or areas of expertise within your practice. The way you respond to questions or complaints can carry a lot of weight; if people see that you take concerns seriously and respond in a timely fashion to requests it shows you care.

Social media is an easy way to get a message out to your patients. Post reminders about flu shots or sports physicals, whatever your specialty might be. Show your support for the local charities and fund drives you participate in. Ask your followers to fill out a patient survey, introduce new staff, link to beneficial health articles. Utilize social media as a new way to get important information to your patients. It’s a fast and free way to get important information and news to your patients.

Having a good social media presence will draw new patients in. It makes you easier to find and many potential new clients do their research for medical recommendations online. The reputation of a medical practice can be influenced by social media which is a good reason to learn how to manage yours.


Via Plus91, Stéphanie Chevrel
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Des images de protéines réalisées par une étudiante de l'IPT en UNE de la revue "Annals of Human Genetics"

Des images de protéines réalisées par une étudiante de l'IPT en UNE de la revue "Annals of Human Genetics" | Institut Pasteur de Tunis-معهد باستور تونس | Scoop.it

Des images de protéines réalisées par Yosra Bouyacoub, étudiante en fin de thèse au laboratoire de Génomique biomédicale et oncogénétique, premier auteur de l'article CYP1B1 Gene Mutations Causing Primary Congenital Glaucoma in Tunisia ont été publiées en UNE de l'édition du mois de juillet de la revue Annals of Human Genetics.

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Les 5 grands défis de la Big Data

Les 5 grands défis de la Big Data | Institut Pasteur de Tunis-معهد باستور تونس | Scoop.it
Prendre la data à bras le corps, c’est comprendre sa raison d’être et maitriser ses arcanes. Et parce que nous n’en sommes qu’à la genèse, il est bon de débuter directement avec les bonnes bases…

Via Vincent Datin
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رمضانكم مبروك

رمضانكم مبروك | Institut Pasteur de Tunis-معهد باستور تونس | Scoop.it
 

 

 

 

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Transcriptomics of differential vector competence: West Nile virus infection in two populations of Culex pipiens quinquefasciatus linked to ovary development

Background:
Understanding mechanisms that contribute to viral dissemination in mosquito vectors will contribute to our ability to interfere with the transmission of viral pathogens that impact public health.

Via Mel Melendrez-Vallard
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