innate immunty & ...
Follow
Find
60 views | +0 today
 
Rescooped by zorro zhang from Science News
onto innate immunty & cancer & inflammation
Scoop.it!

Social Position Drives Gene Regulation of the Immune System

Social Position Drives Gene Regulation of the Immune System | innate immunty & cancer & inflammation | Scoop.it

New research with rhesus macaques shows that dominance rank has a major impact on gene regulation of the immune system


Via Sakis Koukouvis
more...
No comment yet.
Your new post is loading...
Your new post is loading...
Rescooped by zorro zhang from epigenetic in plant development
Scoop.it!

Trends in Microbiology: Epigenetics and the evolution of virulence (2013)

Trends in Microbiology: Epigenetics and the evolution of virulence (2013) | innate immunty & cancer & inflammation | Scoop.it

Pathogens must evolve rapidly in response to host or environmental challenges.Clonal and invasive species adapt quickly despite a lack of genetic diversity.Evasion of host immunity can result from silencing of relevant effectors.Epigenetic reprogramming of gene expression can aid in pathogen adaptation.

 

A feature of pathogenic and invasive organisms is their adaptability when confronted with host and environmental challenges. Recent studies have demonstrated that plant pathogens rely on epigenetic processes for this purpose. Epiallelic variation of effector genes that results in evasion of host immunity is one emerging phenomenon. Another is the epigenetically induced reprogramming and diversification of transcriptional patterns by de-repression of transposable elements. These observations indicate that epigenetic control of gene expression provides a versatile means of generating phenotypic diversity that is adaptable and heritable across generations.


Via Kamoun Lab @ TSL, tianxing84
more...
No comment yet.
Rescooped by zorro zhang from Vitae Herbae (herbal, natural, integrative medicine & health)
Scoop.it!

Lung Cancer Is Associated With “Aged” Immune Cells

Lung Cancer Is Associated With “Aged” Immune Cells | innate immunty & cancer & inflammation | Scoop.it

As cells age, they eventually stop multiplying, a state known as “senescence”. Accumulation of senescent cells is thought to contribute to the symptoms of aging. A study examining T cells, a type of immune cell, found that lung cancer patients had more senescent T cells, much like healthy patients during aging. T cells from both aged individuals and lung cancer patients had increased levels of senescence-promoting proteins, and lower levels of proteins that promote continued cell multiplication. This “artificial aging” of immune cells may weaken the immune system’s ability to attack the cancer. The study’s authors suggest that treatments to ward off senescence in immune cells may in the future help avoid the weakening of the immune system seen in cancer and other aging-related diseases.


Via Cancer Commons, Pasquale Valente
more...
Cancer Commons's curator insight, November 20, 2013 3:30 AM

Journal of Clinical Investigation | Nov 15, 2013

Rescooped by zorro zhang from diabetes and more
Scoop.it!

Joslin Identifies Immune Cells That Promote Growth of Beta Cells in Type 1 Diabetes | Joslin Diabetes Center

Joslin Identifies Immune Cells That Promote Growth of Beta Cells in Type 1 Diabetes | Joslin Diabetes Center | innate immunty & cancer & inflammation | Scoop.it
Joslin Diabetes Center is the world’s foremost institution for diabetes research, clinical care and education.

Via Ellen H Ullman, MSW
more...
Rescooped by zorro zhang from immunology
Scoop.it!

Population genetic tools for dissecting innate immunity in humans : Abstract : Nature Reviews Immunology

RT @NatRevImmunol: Using population genetics to understand innate immunity in humans
http://t.co/68FMQ2xhjl

Via Gilbert Faure au nom de l'ASSIM
more...
No comment yet.
Rescooped by zorro zhang from Science News
Scoop.it!

Social Position Drives Gene Regulation of the Immune System

Social Position Drives Gene Regulation of the Immune System | innate immunty & cancer & inflammation | Scoop.it

New research with rhesus macaques shows that dominance rank has a major impact on gene regulation of the immune system


Via Sakis Koukouvis
more...
No comment yet.
Rescooped by zorro zhang from Science News
Scoop.it!

Your Immune System 'Remembers' Microbes It's Never Fought Before, New Study Says

Your Immune System 'Remembers' Microbes It's Never Fought Before, New Study Says | innate immunty & cancer & inflammation | Scoop.it

Immune cells are like the Hatfields and McCoys of our bodies--once wronged, they never, ever forget. This is how we gain immunity, and it’s why vaccines work: Immune cells develop a memory of an invading pathogen, and they build an alert system to find and fight it should it ever return. But a new study by Stanford researchers adds a new wrinkle to this long-held immune theory. It turns out immune cells can develop this memory-like state even for pathogens they’ve never met. This may come from exposure to harmless microbes -- or the memories may actually be borrowed from other, more experienced cells.


Via Sakis Koukouvis
more...
No comment yet.
Rescooped by zorro zhang from Microbes Inside
Scoop.it!

Conserved Shifts in the Gut Microbiota Due to Gastric Bypass Reduce Host Weight and Adiposity

Conserved Shifts in the Gut Microbiota Due to Gastric Bypass Reduce Host Weight and Adiposity | innate immunty & cancer & inflammation | Scoop.it

Via Clara Belzer
more...
Clara Belzer's curator insight, March 30, 2013 6:32 AM

In many people with type 2 diabetes, the disease vanished almost immediately after a gastric by-pass, too quickly to be explained by the gradual weight loss that happens later. The authors decribes taht weight loss and operation ar acompanied with a boost in three types of bacteria called Bacteroidetes, Verrucomicrobia, and Proteobacteria. These findings provide  empirical support for the claim that changes in the gut microbiota contribute to reduced host weight and adiposity after gastric bypass surgery.