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Immunology for University Students
Resources and Material for Lecturers and Students - Immunology (University level)
Curated by Alfredo Corell
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A New Subset of Negative Regulatory CD8 T Cells in Human PBMC

A New Subset of Negative Regulatory CD8 T Cells in Human PBMC | Immunology for University Students | Scoop.it
Regulatory CD8 T cells suppress activated CD4 T cells and have proposed roles in various human diseases including multiple sclerosis, ovarian carcinoma and infection with HIV, and many subsets have been described using various markers.
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A population of CD3+CD8+CD161−CD56+ regulatory CD8 T cells were identified in PBMC and compared with conventional CD8 T cells (CD3+CD8+CD161−CD56-) and NKT cells (CD3+CD8+CD161+CD56+).

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A New Subset of Negative Regulatory CD8 T Cells in Human PBMC

A New Subset of Negative Regulatory CD8 T Cells in Human PBMC | Immunology for University Students | Scoop.it
Regulatory CD8 T cells suppress activated CD4 T cells and have proposed roles in various human diseases including multiple sclerosis, ovarian carcinoma and infection with HIV, and many subsets have been described using various markers.
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Regulation of Adaptive Immunity; The Role of Interleukin-10 | Frontiers in Immunological Tolerance

Regulation of Adaptive Immunity; The Role of Interleukin-10 | Frontiers in Immunological Tolerance | Immunology for University Students | Scoop.it
Frontiers | Regulation of Adaptive Immunity; The Role of Interleukin-10 | Frontiers in Immunological Tolerance publishes articles on the most outstanding discoveries across the research spectrum of Frontiers | Regulation of Adaptive Immunity; The...
Alfredo Corell's insight:
Front. Immunol., 31 May 2013 | doi: 10.3389/fimmu.2013.00129 

Regulation of adaptive immunity; the role of interleukin-10T. H. Sky Ng, Graham J. Britton, Elaine V. Hill, Johan Verhagen, Bronwen R. Burton and David C. Wraith*
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T cell tolerance and immunity to commensal bacteria- Current Opinion in Immunology -

T cell tolerance and immunity to commensal bacteria- Current Opinion in Immunology - | Immunology for University Students | Scoop.it

T cell tolerance and immunity to commensal bacteria

Katherine M Nutsch,Chyi-Song Hsieh

Department of Medicine, Division of Rheumatology, Washington University School of Medicine, St. Louis, MO 63110, United States

http://dx.doi.org/10.1016/j.coi.2012.04.009,

 

Highlights

► Tolerance is required to commensal bacteria and depends on regulatory T cells. ► Regulatory T cells specific to commensal bacteria are generated from naïve T cells in the periphery. ► Bacterial products can facilitate Treg cell function via the induction of IL-10, an immunosuppressive cytokine. ► Specific commensal bacterial species induce inflammatory or tolerogenic T cell responses in the gut.

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