Immunology for University Students
13.4K views | +0 today
Follow
Immunology for University Students
Resources and Material for Lecturers and Students - Immunology (University level)
Curated by Alfredo Corell
Your new post is loading...
Your new post is loading...
Scooped by Alfredo Corell
Scoop.it!

Sanidad estudia levantar el bloqueo a la vacuna de la varicela

Sanidad estudia levantar el bloqueo a la vacuna de la varicela | Immunology for University Students | Scoop.it
Las sociedades científicas reclaman la vacunación a los 12 meses y no a los 12 años
Alfredo Corell's insight:

El Ministerio de Sanidad estudia levantar el bloqueo a la vacuna de la varicela que aplicó hace dos años, cuando Ana Mato era la titular del departamento. El actual ministro, Alfonso Alonso, ha reconocido hoy que hablará con las comunidades autónomas de la posibilidad de volver a administrar esta vacuna a edades tempranas. Actualmente, y pese a la recomendación unánime de los pediatras, esta inmunización no se puede recibir en España hasta los 12 años. Sanidad llegó a retirar de las farmacias Varivax, la vacuna de Sanofi Pasteur MSD, para evitar que los padres la compraran por su cuenta.

more...
No comment yet.
Scooped by Alfredo Corell
Scoop.it!

Influence of the microbiota on vaccine effectiveness

Influence of the microbiota on vaccine effectiveness | Immunology for University Students | Scoop.it
Publication stage: In Press Corrected Proof
Alfredo Corell's insight:


Highlights


  • Gut microbial composition affects immune system function.
  • The immune system influences host microbial populations.
  • Microbiota diversity and composition may impact upon vaccine efficacy.
  • A mechanistic understanding should inform future vaccination strategies.



Studies of the relationship between the microbiome and the development and function of the immune system are demonstrating novel concepts that could significantly alter the way we treat disease and promote wellness. Several diseases, including inflammatory bowel disease, allergy/asthma, and diabetes, are associated with changes in composition of the microbiome. Recent findings suggest novel complex mechanisms by which the microbiome impacts immune cell development and differentiation. A major implication of these findings is that the composition of microbiome may ultimately affect vaccine efficacy. We explore here the potential role of the microbiome in vaccine responses in the context of our growing understanding of the relationship between the gastrointestinal microbiota, resident immune cell populations, and systemic immunity.

more...
No comment yet.
Scooped by Alfredo Corell
Scoop.it!

The effects of anti-vaccine conspiracy theories on vaccination intentions | Vaccinews Blog

The effects of anti-vaccine conspiracy theories on vaccination intentions | Vaccinews Blog | Immunology for University Students | Scoop.it
A belief in anti-vaccine conspiracy theories may have significant and detrimental consequences for children's health, new research from the University has shown.
Alfredo Corell's insight:

Daniel Jolley said: ‘This research is timely in the face of declining vaccination rates and recent outbreaks of vaccinated-against diseases in the UK, such as measles. Our studies demonstrate that anti-vaccine conspiracy theories may present a barrier to vaccine uptake, which may potentially have significant and detrimental consequences for children’s health.’


Go to PLOS one publication: http://www.vaccinews.net/downloads/blog/March_3.pdf 

more...
No comment yet.
Scooped by Alfredo Corell
Scoop.it!

El movimiento antivacunas amenaza la salud mundial

El movimiento antivacunas amenaza la salud mundial | Immunology for University Students | Scoop.it
Las vacunas son uno de los pilares básicos entre los que se asienta la medicina científica y la sanidad actuales.  Y aunque desde nuestra visión occidental marcada por el ideal de progreso y supera...
Alfredo Corell's insight:

Estamos llegando a límites insospechados. El movimiento anti-vacunas que últimamente está creciendo (por poner un ejemplo están llegando ya a Valencia las llamadas "small-pox parties") puede poner en jaque el sistema sanitario de muchos países.

more...
No comment yet.
Scooped by Alfredo Corell
Scoop.it!

Autoimmunity (self immunity) USMLE video animation

This immunology video explains autoimmunity and the effect of autoimmune symptoms in human body. For more information, log on to- http://shomusbiology.weebly...
Alfredo Corell's insight:

a simple and accesible video for Immunology university students

more...
No comment yet.
Scooped by Alfredo Corell
Scoop.it!

Subcutaneous immunoglobulin therapy at home - Nursing Times

Subcutaneous immunoglobulin therapy at home - Nursing Times | Immunology for University Students | Scoop.it

Subcutaneous immunoglobulin therapy at home
Nursing Times
... home, rather than with intravenous immunoglobulin (IVIg) therapy in hospital.

Alfredo Corell's insight:
5 KEY POINTSImmuno-globulins are antibodies prepared from plasma that help keep the body free from infectionBefore the introduction of antibiotics, patients diagnosed with antibody deficiency died prematurely from acute respiratory infectionsSubcutaneous immuno-globulin (SCIg) therapy reduces patients’ susceptibility to recurrent acute and chronic respiratory infectionsManaging their own treatment gives patients greater control over their condition and promotes concordanceDelivering SCIg therapy at home saves the NHS money and is popular with patients
more...
No comment yet.
Scooped by Alfredo Corell
Scoop.it!

.: VacciNews - Facts about vaccination and immunization :.

.: VacciNews - Facts about vaccination and immunization :. | Immunology for University Students | Scoop.it
VacciNews.net provides up-to-date information to the public, media, health professionals and policy makers to help them understand the facts about vaccines and immunization.
Alfredo Corell's insight:

Great web page with all necessary information for the public and for professionals.

more...
No comment yet.
Scooped by Alfredo Corell
Scoop.it!

My collection of Educational Immunopathology and Immunology images and videos is growing. Suggestions wellcomed

My collection of Educational Immunopathology and Immunology images and videos is growing. Suggestions wellcomed | Immunology for University Students | Scoop.it
more...
No comment yet.
Scooped by Alfredo Corell
Scoop.it!

If helper T cells have nothing to help, they kill their host

If helper T cells have nothing to help, they kill their host | Immunology for University Students | Scoop.it
For vaccines, CD4+ T cells can spell trouble

The ideal vaccine elicits immune memory—either antibodies or memory T cells—to protect the host from subsequent infections. T cell–mediated immunity requires both helper CD4+ T cells and cytotoxic CD8+ T cells to kill virus-infected cells. But what happens when a vaccine only elicits CD4+ memory T cells? Penaloza-MacMaster et al. probed this question by giving mice a vaccine that generated only memory CD4+ T cells against lymphocytic choriomeningitis virus (LCMV). Instead of protecting mice against chronic LCMV, vaccinated mice developed massive inflammation and died. Virus-specific CD8+ T cells or antibodies protected mice from the pathology. These results may have implications for vaccines against chronic viruses such as HIV.

Science 16 January 2015: 
Vol. 347 no. 6219 pp. 278-282 
DOI: 10.1126/science.aaa2148

Alfredo Corell's insight:

CD4 T cells promote innate and adaptive immune responses, but how vaccine-elicited CD4 T cells contribute to immune protection remains unclear. We evaluated whether induction of virus-specific CD4 T cells by vaccination would protect mice against infection with chronic lymphocytic choriomeningitis virus (LCMV). Immunization with vaccines that selectively induced CD4 T cell responses resulted in catastrophic inflammation and mortality after challenge with a persistent strain of LCMV. Immunopathology required antigen-specific CD4 T cells and was associated with a cytokine storm, generalized inflammation, and multi-organ system failure. Virus-specific CD8 T cells or antibodies abrogated the pathology. These data demonstrate that vaccine-elicited CD4 T cells in the absence of effective antiviral immune responses can trigger lethal immunopathology.

more...
No comment yet.
Scooped by Alfredo Corell
Scoop.it!

First Tests of Ebola Vaccine Appear at Least a Month Away - Bloomberg

First Tests of Ebola Vaccine Appear at Least a Month Away - Bloomberg | Immunology for University Students | Scoop.it
Bloomberg First Tests of Ebola Vaccine Appear at Least a Month Away Bloomberg It would be risky to perform initial safety trials of a Ebola vaccine in Africa where patients may be far from a good hospital that can provide modern medical care should...
Alfredo Corell's insight:

There is no cure for Ebola. The virus has killed 1,069 of 1,975 people afflicted in the four West African nations as of Aug. 11, the WHO said yesterday.

The disease is normally treated by keeping patients hydrated, replacing lost blood and using antibiotics to fight opportunistic infections. The hope is that a patient’s immune system will eventually fight off the virus’s aggressive attack.

more...
No comment yet.
Scooped by Alfredo Corell
Scoop.it!

The weak link: adult immunisations

The weak link: adult immunisations | Immunology for University Students | Scoop.it
Adults account for 95 percent of individuals who die from vaccine-preventable diseases (The weak link: adult immunisations. Adults account for 95% of individuals who die from vaccine-preventable diseases.
Alfredo Corell's insight:

Adults account for 95 percent of individuals who die from vaccine-preventable diseases. Yet vaccination rates among adults remain “very low”. The latest feature film from Chain of Protection discusses the importance and need for adult immunisation in the fight against preventable infectious diseases.

more...
No comment yet.
Scooped by Alfredo Corell
Scoop.it!

Obtienen nanocápsulas con actividad antitumoral en líneas celulares de cáncer de mama

Obtienen nanocápsulas con actividad antitumoral en líneas celulares de cáncer de mama | Immunology for University Students | Scoop.it
SINC, Servicio de Información y Noticias Científicas, plataforma multimedia de comunicación científica (Obtienen nanocápsulas con actividad antitumoral en líneas celulares de cáncer de mama http://t.co/AZYAuzAGh4)...
Alfredo Corell's insight:

Enlace al artículo científico:

http://pubs.acs.org/doi/abs/10.1021/bm401103t 

more...
No comment yet.
Scooped by Alfredo Corell
Scoop.it!

The Quest for an HIV-1 Vaccine — Moving Forward — NEJM

The Quest for an HIV-1 Vaccine — Moving Forward — NEJM | Immunology for University Students | Scoop.it

Perspective from The New England Journal of Medicine — The Quest for an HIV-1 Vaccine — Moving Forward 

Dan H. Barouch, M.D., Ph.D.

N Engl J Med 2013; 369:2073-2076

November 28, 2013DOI: 10.1056/NEJMp1312711

Alfredo Corell's insight:

Testing only four HIV-1 vaccine concepts for clinical efficacy over the past three decades is insufficient given the scope of the global HIV-1 epidemic. We clearly need more “shots on goal.” We should therefore accelerate the advancement of a diverse series of novel and promising HIV-1 vaccine candidates into clinical efficacy trials over the next several years.

more...
No comment yet.
Scooped by Alfredo Corell
Scoop.it!

Taking probiotics during pregnancy has no effect on asthma rate amoung infants - Meta-analysis

Taking probiotics during pregnancy has no effect on asthma rate amoung infants - Meta-analysis | Immunology for University Students | Scoop.it
AbstractObjective To evaluate the association of probiotic supplementation during pregnancy or infancy with childhood asthma and wheeze.Design Systematic review and meta-analysis of randomised controlled trials.Data sources Medline, Embase, and...
Alfredo Corell's insight:

BMJ. 2013 Dec 4;347:f6471. doi: 10.1136/bmj.f6471.Probiotic supplementation during pregnancy or infancy for the prevention of asthma and wheeze: systematic review and meta-analysis.Azad MB, Coneys JG, Kozyrskyj AL, Field CJ, Ramsey CD, Becker AB, Friesen C, Abou-Setta AM, Zarychanski R.

 

 

 

Conclusions We found no evidence to support a protective association between perinatal use of probiotics and doctor diagnosed asthma or childhood wheeze. Randomised controlled trials to date have not yielded sufficient evidence to recommend probiotics for the primary prevention of these disorders. Extended follow-up of existing trials, along with further clinical and basic research, are needed to accurately define the role of probiotics in the prevention of childhood asthma.

 

Press news:http://www.news-medical.net/news/20131209/Taking-probiotics-during-pregnancy-has-no-effect-on-asthma-rate-amoung-infants.aspx ;

more...
No comment yet.
Scooped by Alfredo Corell
Scoop.it!

Immune System: Diseases, Disorders & Function - a very "basics" post

Immune System: Diseases, Disorders & Function - a very "basics" post | Immunology for University Students | Scoop.it
The job of the immune system is to protect against disease.
more...
No comment yet.